-
1
-
-
78649816539
-
1Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8
-
1Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8. J Clin Invest 2010;120:4236-4250.
-
(2010)
J Clin Invest
, vol.120
, pp. 4236-4250
-
-
Bergin, D.A.1
Reeves, E.P.2
Meleady, P.3
-
5
-
-
34249332725
-
1-Antitrypsin regulates CD14 expression and soluble CD14 levels in human monocytes in vitro
-
1-Antitrypsin regulates CD14 expression and soluble CD14 levels in human monocytes in vitro. Int J Biochem Cell Biol 2007;39:1165-1176.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 1165-1176
-
-
Nita, I.M.1
Serapinas, D.2
Janciauskiene, S.M.3
-
6
-
-
0031893793
-
1-antitrypsin and protease complexation is induced by lipopolysaccharide, interleukin-1β, and tumor necrosis factor-α in monocytes
-
1-antitrypsin and protease complexation is induced by lipopolysaccharide, interleukin-1β, and tumor necrosis factor-α in monocytes. Am J Respir Crit Care Med 1998;157:246-255.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 246-255
-
-
Knoell, D.L.1
Ralston, D.R.2
Coulter, K.R.3
-
7
-
-
0030610007
-
1-proteinase inhibitor by human lung-derived epithelial cells
-
1-proteinase inhibitor by human lung-derived epithelial cells. J Biol Chem 1997;272:8250-8255.
-
(1997)
J Biol Chem
, vol.272
, pp. 8250-8255
-
-
Cichy, J.1
Potempa, J.2
Travis, J.3
-
9
-
-
0026755363
-
The mechanism of Z α1-antitrypsin accumulation in the liver
-
Lomas DA, Evans DL, Finch JT, et al. The mechanism of Z α1-antitrypsin accumulation in the liver. Nature 1992;357:605-607.
-
(1992)
Nature
, vol.357
, pp. 605-607
-
-
Lomas, D.A.1
Evans, D.L.2
Finch, J.T.3
-
10
-
-
0013828812
-
Studies in α1-antitrypsin deficiency
-
Eriksson S. Studies in α1-antitrypsin deficiency. Acta Med Scand Suppl 1965;432:1-85.
-
(1965)
Acta Med Scand Suppl
, vol.432
, pp. 1-85
-
-
Eriksson, S.1
-
12
-
-
19944430698
-
Polymers of Z α1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo
-
Mahadeva R, Atkinson C, Li Z, et al. Polymers of Z α1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo. Am J Pathol 2005;166:377-386.
-
(2005)
Am J Pathol
, vol.166
, pp. 377-386
-
-
Mahadeva, R.1
Atkinson, C.2
Li, Z.3
-
13
-
-
0036014834
-
1-antitrypsin are chemotactic for human neutrophils: A new paradigm for the pathogenesis of emphysema
-
1-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema. Am J Respir Cell Mol Biol 2002;26:723-730.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 723-730
-
-
Parmar, J.S.1
Mahadeva, R.2
Reed, B.J.3
-
14
-
-
80051635385
-
1-antitrypsin by cigarette smoke induces polymerization: A novel mechanism of early-onset emphysema
-
1-antitrypsin by cigarette smoke induces polymerization: a novel mechanism of early-onset emphysema. Am J Respir Cell Mol Biol 2011;45:261-269.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 261-269
-
-
Alam, S.1
Li, Z.2
Janciauskiene, S.3
-
15
-
-
2442488539
-
1-antitrypsin polymerizes in the lung and acts as a neutrophil chemoattractant
-
1-antitrypsin polymerizes in the lung and acts as a neutrophil chemoattractant. Chest 2004;125:1952-1957.
-
(2004)
Chest
, vol.125
, pp. 1952-1957
-
-
Mulgrew, A.T.1
Taggart, C.C.2
Lawless, M.W.3
-
16
-
-
33749492425
-
Endoplasmic reticulum stress signaling in disease
-
Marciniak SJ, Ron D. Endoplasmic reticulum stress signaling in disease. Physiol Rev 2006;86:1133-1149.
-
(2006)
Physiol Rev
, vol.86
, pp. 1133-1149
-
-
Marciniak, S.J.1
Ron, D.2
-
18
-
-
8644282751
-
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
-
Deng J, Lu PD, Zhang Y, et al. Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol 2004;24:10161-10168.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10161-10168
-
-
Deng, J.1
Lu, P.D.2
Zhang, Y.3
-
19
-
-
0037385313
-
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
-
Iwakoshi NN, Lee AH, Vallabhajosyula P, et al. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol 2003;4:321-329.
-
(2003)
Nat Immunol
, vol.4
, pp. 321-329
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Vallabhajosyula, P.3
-
20
-
-
47049098902
-
Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-p induction via X-box binding protein 1
-
Smith JA, Turner MJ, DeLay ML, et al. Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN-p induction via X-box binding protein 1. Eur J Immunol 2008;38:1194-1203.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1194-1203
-
-
Smith, J.A.1
Turner, M.J.2
DeLay, M.L.3
-
21
-
-
69249104575
-
Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins
-
Kroeger H, Miranda E, MacLeod I, et al. Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins. J Biol Chem 2009;284:22793-22802.
-
(2009)
J Biol Chem
, vol.284
, pp. 22793-22802
-
-
Kroeger, H.1
Miranda, E.2
MacLeod, I.3
-
22
-
-
77954597127
-
1-antitrypsin Z and reduces hepatic fibrosis
-
1-antitrypsin Z and reduces hepatic fibrosis. Science 2010;329:229-232.
-
(2010)
Science
, vol.329
, pp. 229-232
-
-
Hidvegi, T.1
Ewing, M.2
Hale, P.3
-
25
-
-
84876803937
-
Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in oc1-antitrypsin deficiency
-
Ordonez A, Snapp EL, Tan L, et al. Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in oc1-antitrypsin deficiency. Hepatology 2013;57:2049-2060.
-
(2013)
Hepatology
, vol.57
, pp. 2049-2060
-
-
Ordonez, A.1
Snapp, E.L.2
Tan, L.3
-
26
-
-
77952770299
-
Evidence for unfolded protein response activation in monocytes from individuals with α-1 antitrypsin deficiency
-
Carroll TP, Greene CM, O'Connor CA, et al. Evidence for unfolded protein response activation in monocytes from individuals with α-1 antitrypsin deficiency. J Immunol 2010;184:4538-4546.
-
(2010)
J Immunol
, vol.184
, pp. 4538-4546
-
-
Carroll, T.P.1
Greene, C.M.2
O'Connor, C.A.3
-
27
-
-
0030680913
-
Chronic obstructive pulmonary disease: Role of bronchiolar mast cells and macrophages
-
Grashoff WF, Sont JK, Sterk PJ, et al. Chronic obstructive pulmonary disease: role of bronchiolar mast cells and macrophages. Am J Pathol 1997;151:1785-1790.
-
(1997)
Am J Pathol
, vol.151
, pp. 1785-1790
-
-
Grashoff, W.F.1
Sont, J.K.2
Sterk, P.J.3
-
28
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
-
29
-
-
80052149236
-
Diversity and plasticity of mononuclear phagocytes
-
Gordon S, Mantovani A. Diversity and plasticity of mononuclear phagocytes. Eur J Immunol 2011;41:2470-2472.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2470-2472
-
-
Gordon, S.1
Mantovani, A.2
-
30
-
-
84857883847
-
Macrophage plasticity and polarization: In vivo veritas
-
Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 2012;122:787-795.
-
(2012)
J Clin Invest
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
31
-
-
12144288237
-
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco) bacteria
-
Verreck FA, de Boer T, Langenberg DM, et al. Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco) bacteria. Proc Natl Acad Sci USA 2004;101:4560-4565.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4560-4565
-
-
Verreck, F.A.1
De Boer, T.2
Langenberg, D.M.3
-
32
-
-
33745067210
-
IL-10-producing macrophages preferentially clear early apoptotic cells
-
Xu W, Roos A, Schlagwein N, et al. IL-10-producing macrophages preferentially clear early apoptotic cells. Blood 2006;107:4930-4937.
-
(2006)
Blood
, vol.107
, pp. 4930-4937
-
-
Xu, W.1
Roos, A.2
Schlagwein, N.3
-
33
-
-
49649093608
-
Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFp-1
-
Savage ND, de Boer T, Walburg KV, et al. Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFp-1. J Immunol 2008;181:2220-2226.
-
(2008)
J Immunol
, vol.181
, pp. 2220-2226
-
-
Savage, N.D.1
De Boer, T.2
Walburg, K.V.3
-
34
-
-
84892527974
-
Altered macrophage function in chronic obstructive pulmonary disease
-
Hiemstra PS. Altered macrophage function in chronic obstructive pulmonary disease. Ann Am Thorac Soc 2013;10:Suppl., S180-S185.
-
(2013)
Ann Am Thorac Soc
, vol.10
, pp. S180-S185
-
-
Hiemstra, P.S.1
-
35
-
-
34250757699
-
Identification of individuals with oc1-antitrypsin deficiency by a targeted screening program
-
Bals R, Koczulla R, Kotke V, et al. Identification of individuals with oc1-antitrypsin deficiency by a targeted screening program. Respir Med 2007;101:1708-1714.
-
(2007)
Respir Med
, vol.101
, pp. 1708-1714
-
-
Bals, R.1
Koczulla, R.2
Kotke, V.3
-
37
-
-
84863586566
-
A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress
-
van Schadewijk A, van't Wout EF, Stolk J, et al. A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress. Cell Stress Chaperones 2012;17:275-279.
-
(2012)
Cell Stress Chaperones
, vol.17
, pp. 275-279
-
-
Van Schadewijk, A.1
Van't Wout, E.F.2
Stolk, J.3
-
38
-
-
10044269621
-
Increased GADD gene expression in human colon epithelial cells exposed to deoxycholate
-
Scott DW, Mutamba S, Hopkins RG, et al. Increased GADD gene expression in human colon epithelial cells exposed to deoxycholate. J Cell Physiol 2005;202:295-303.
-
(2005)
J Cell Physiol
, vol.202
, pp. 295-303
-
-
Scott, D.W.1
Mutamba, S.2
Hopkins, R.G.3
-
39
-
-
0026050850
-
Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps
-
Lytton J, Westlin M, Hanley MR. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J Biol Chem 1991;266:17067-17071.
-
(1991)
J Biol Chem
, vol.266
, pp. 17067-17071
-
-
Lytton, J.1
Westlin, M.2
Hanley, M.R.3
-
40
-
-
0030603101
-
2+ and reactive oxygen intermediates as messengers
-
2+ and reactive oxygen intermediates as messengers. FEBS Lett 1996;392:129-136.
-
(1996)
FEBS Lett
, vol.392
, pp. 129-136
-
-
Pahl, H.L.1
Baeuerle, P.A.2
-
41
-
-
0024334846
-
Interferon beta 2/interleukin 6 modulates synthesis of alpha 1-antitrypsin in human mononuclear phagocytes and in human hepatoma cells
-
Perlmutter DH, May LT, Sehgal PB. Interferon beta 2/interleukin 6 modulates synthesis of alpha 1-antitrypsin in human mononuclear phagocytes and in human hepatoma cells. J Clin Invest 1989;84:138-144.
-
(1989)
J Clin Invest
, vol.84
, pp. 138-144
-
-
Perlmutter, D.H.1
May, L.T.2
Sehgal, P.B.3
-
43
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon F, Chen X, Lee AH, et al. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol 2010;11:411-418.
-
(2010)
Nat Immunol
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.H.3
-
44
-
-
84863663085
-
Induction of GADD34 is necessary for dsRNA-dependent interferon-p production and participates in the control of Chikungunya virus infection
-
Clavarino G, Claudio N, Couderc T, et al. Induction of GADD34 is necessary for dsRNA-dependent interferon-p production and participates in the control of Chikungunya virus infection. PLoS Pathog 2012;8:e1002708
-
(2012)
PLoS Pathog
, vol.8
, pp. e1002708
-
-
Clavarino, G.1
Claudio, N.2
Couderc, T.3
-
46
-
-
10644267224
-
Circulating monocytes from healthy individuals and COPD patients
-
Aldonyte R, Jansson L, Piitulainen E, et al. Circulating monocytes from healthy individuals and COPD patients. Respir Res 2003;4:11.
-
(2003)
Respir Res
, vol.4
, pp. 11
-
-
Aldonyte, R.1
Jansson, L.2
Piitulainen, E.3
-
47
-
-
33646455658
-
Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-γ- and CD40L-mediated costimulation
-
Verreck FA, de Boer T, Langenberg DM, et al. Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-γ- and CD40L-mediated costimulation. J Leukoc Biol 2006;79:285-293.
-
(2006)
J Leukoc Biol
, vol.79
, pp. 285-293
-
-
Verreck, F.A.1
De Boer, T.2
Langenberg, D.M.3
-
48
-
-
76049130197
-
Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility
-
Chan G, Nogalski MT, Yurochko AD. Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility. Proc Natl Acad Sci USA 2009;106:22369-22374.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 22369-22374
-
-
Chan, G.1
Nogalski, M.T.2
Yurochko, A.D.3
-
50
-
-
79151473459
-
Monocyte and macrophage heterogeneity and Toll-like receptors in the lung
-
Schneberger D, Aharonson-Raz K, Singh B. Monocyte and macrophage heterogeneity and Toll-like receptors in the lung. Cell Tissue Res 2011;343:97-106.
-
(2011)
Cell Tissue Res
, vol.343
, pp. 97-106
-
-
Schneberger, D.1
Aharonson-Raz, K.2
Singh, B.3
|