Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency

Hepatology

Volumn 57, Issue 5, 2013, Pages 2049-2060

  Ordóñez, Adriana ^a   Snapp, Erik L ^b   Tan, Lu ^a   Miranda, Elena ^a,c   Marciniak, Stefan J ^a   Lomas, David A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; POLYMER; TUNICAMYCIN;

ALLELE; ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; BLEACHING; CELL EXPANSION; CONTROLLED STUDY; DEGRADATION; DEPLETION; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; LIVER DISEASE; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE;

ALPHA 1-ANTITRYPSIN; ALPHA 1-ANTITRYPSIN DEFICIENCY; ANIMALS; CELL LINE; CRICETINAE; CRICETULUS; ENDOPLASMIC RETICULUM STRESS; FEMALE; INCLUSION BODIES; MODELS, ANIMAL; MUTATION; POLYMERS; PROTEINS; STRESS, PHYSIOLOGICAL; UNFOLDED PROTEIN RESPONSE;

EID: 84876803937     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26173     Document Type: Article

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