A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1-antitrypsin deficiency

Hepatology

Volumn 52, Issue 3, 2010, Pages 1078-1088

  Miranda, Elena ^a,b   Pérez, Juan ^a,c   Ekeowa, Ugo I ^a   Hadzic, Nedim ^d   Kalsheker, Noor ^e   Gooptu, Bibek ^f   Portmann, Bernard ^d   Belorgey, Didier ^a   Hill, Marian ^e   Chambers, Susan ^d   Teckman, Jeff ^g   Alexander, Graeme J ^a   Marciniak, Stefan J ^a   Lomas, David A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF MÁLAGA   (Spain)

^d KING S COLLEGE HOSPITAL   (United Kingdom)

^e UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^f UNIVERSITY OF LONDON   (United Kingdom)

^g SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2C1 MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; POLYMER; UNCLASSIFIED DRUG; ALPHA 1 ANTITRYPSIN; EPITOPE;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; CHILD; CONFORMATION; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; JAUNDICE; LIVER DISEASE; MALE; MUTATION; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; WILD TYPE; ANTIBODY SPECIFICITY; GENETICS; IMMUNOLOGY; INFANT; LIVER; METABOLISM; NEWBORN; NEWBORN JAUNDICE; PROTEIN TERTIARY STRUCTURE;

ALPHA 1-ANTITRYPSIN; ALPHA 1-ANTITRYPSIN DEFICIENCY; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ENDOPLASMIC RETICULUM; EPITOPES; HUMANS; INFANT; INFANT, NEWBORN; JAUNDICE, NEONATAL; LIVER; LIVER DISEASES; MALE; MUTATION; POLYMERS; PROTEIN STRUCTURE, TERTIARY;

EID: 77956389382     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.23760     Document Type: Article

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