Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling

Cellular Signalling

Volumn 25, Issue 4, 2013, Pages 736-742

  Chandrasekera, P Charukeshi ^a   Wan, Tina C ^b   Gizewski, Elizabeth T ^b   Auchampach, John A ^b   Lasley, Robert D ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Adrenergic receptors; Adenosine receptor; G protein coupled receptors; Heterodimerization

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ADENOSINE A1 RECEPTOR AGONIST; RECOMBINANT PROTEIN;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; ENZYME PHOSPHORYLATION; HETERODIMERIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; BIOSYNTHESIS; CELL STRAIN HEK293; CHEMISTRY; DIMERIZATION; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HEART MUSCLE; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; SIGNAL TRANSDUCTION;

ADENOSINE A1 RECEPTOR AGONISTS; CYCLIC AMP; DIMERIZATION; HEK293 CELLS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCARDIUM; PHOSPHORYLATION; PROTEIN BINDING; RECEPTOR, ADENOSINE A1; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84873252073     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.12.022     Document Type: Article

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