Topoisomerase inhibition accelerates gene expression after adeno-associated virus-mediated gene transfer to the mammalian heart

Molecular Therapy

Volumn 15, Issue 4, 2007, Pages 764-771

  Prasad, Konkal Matt R ^a   Xu, Yaqin ^a   Yang, Zequan ^a   Toufektsian, Marie Claire ^a   Berr, Stuart S ^b   French, Brent A ^a,b  

^a University of Virginia   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DNA TOPOISOMERASE; DOUBLE STRANDED DNA; FIREFLY LUCIFERASE; PARVOVIRUS VECTOR; PLACEBO; SINGLE STRANDED DNA;

ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; C57BL MOUSE; CARDIOVASCULAR GENE THERAPY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; GENE CONVERSION; GENE EXPRESSION; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE MASS; HEART OUTPUT; IN VITRO STUDY; ISCHEMIC HEART DISEASE; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; REPORTER GENE; SOUTHERN BLOTTING; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BASE SEQUENCE; CAMPTOTHECIN; CORONARY DISEASE; DEPENDOVIRUS; DNA PRIMERS; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; ENZYME INHIBITORS; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; LUCIFERASES, FIREFLY; LUMINESCENT MEASUREMENTS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIUM; RECOMBINANT PROTEINS; TRANSDUCTION, GENETIC;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS - 2; MAMMALIA; MUS;

EID: 33947288478     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300071     Document Type: Article

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