Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5

Circulation Research

Volumn 111, Issue 9, 2012, Pages 1147-1156

  Inagawa, Kohei ^a   Miyamoto, Kazutaka ^a   Yamakawa, Hiroyuki ^a   Muraoka, Naoto ^a   Sadahiro, Taketaro ^a   Umei, Tomohiko ^a   Wada, Rie ^a   Katsumata, Yoshinori ^a   Kaneda, Ruri ^a   Nakade, Koji ^b   Kurihara, Chitose ^b   Obata, Yuichi ^b   Miyake, Koichi ^c   Fukuda, Keiichi ^a   Ieda, Masaki ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b RIKEN BIORESOURCE CENTER   (Japan)

^c NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

cardiomyocytes; fibroblasts; myocardial infarction; reprogramming; transcription factors

Indexed keywords

ALPHA ACTININ; CYCLOSPORIN A; GREEN FLUORESCENT PROTEIN; MYOSIN HEAVY CHAIN ALPHA; RETROVIRUS VECTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR MEF2C; TRANSCRIPTION FACTOR TBX5; TROPONIN T; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; FIBROBLAST; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO GENE TRANSFER; IN VITRO STUDY; IN VIVO GENE TRANSFER; IN VIVO STUDY; MALE; MOUSE; MUSCLE REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOMERE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; CELL DIFFERENTIATION; FIBROBLASTS; GATA4 TRANSCRIPTION FACTOR; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; MALE; MICE; MICE, INBRED ICR; MICE, NUDE; MICE, TRANSGENIC; MODELS, ANIMAL; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; MYOGENIC REGULATORY FACTORS; REGENERATION; RETROVIRIDAE; T-BOX DOMAIN PROTEINS;

EID: 84867704611     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.271148     Document Type: Article

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