Actin depolymerization under force is governed by lysine 113:glutamic acid 195-mediated catch-slip bonds

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 13, 2013, Pages 5022-5027

  Lee, Cho Yin ^a,b,c   Lou, Jizhong ^b,d   Wen, Kuo Kuang ^e   Melissa McKane, ^e   Eskin, Suzanne G ^a,b   Ono, Shoichiro ^f   Chien, Shu ^g   Rubenstein, Peter A ^e   Zhu, Cheng ^a,b   McIntire, Larry V ^a,b  

^a Emory University   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d INSTITUTE OF BIOPHYSICS   (China)

^e UNIVERSITY OF IOWA   (United States)

^f EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Mechanosensing; Mechanotransduction; Nemaline myopathy; Single molecule force spectroscopy

Indexed keywords

ACTIN; F ACTIN; G ACTIN; GLUTAMIC ACID; LYSINE; PROTEIN CAPZ; SERINE;

ACTIN FILAMENT; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL FUNCTION; CYTOSKELETON; DEPOLYMERIZATION; DISSOCIATION; KINETICS; LIFESPAN; MOLECULAR DYNAMICS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TENSILE STRENGTH; YEAST;

ACTIN CYTOSKELETON; ACTINS; AMINO ACID SUBSTITUTION; ANIMALS; AVIAN PROTEINS; CHICKENS; HUMANS; MICROSCOPY, ATOMIC FORCE; MUTATION, MISSENSE; RABBITS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84875515145     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1218407110     Document Type: Article

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