Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts

Inflammatory Bowel Diseases

Volumn 19, Issue 5, 2013, Pages 891-903

  Johnson, Laura A ^a   Rodansky, Eva S ^a   Sauder, Kay L ^a   Horowitz, Jeffrey C ^a   Mih, Justin D ^b   Tschumperlin, Daniel J ^b   Higgins, Peter D ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Crohn's disease; Extracellular matrix; Fibroblast; Fibrosis; Inflammatory bowel disease; Stiffness

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; MATRIX METALLOPROTEINASE;

ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR PARAMETERS; CONTROLLED STUDY; CORRELATION ANALYSIS; EX VIVO STUDY; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX STIFFNESS; FIBROBLAST; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTESTINAL FIBROSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; COLON; CONSTRICTION, PATHOLOGIC; CROHN DISEASE; FIBROBLASTS; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTESTINAL MUCOSA; MATRIX METALLOPROTEINASES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84876404631     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0b013e3182813297     Document Type: Article

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