Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice

Journal of Hepatology

Volumn 64, Issue 1, 2016, Pages 110-117

  Lei, Xiao Feng ^a   Fu, Wenguang ^a,b   Kim Kaneyama, Joo Ri ^a   Omoto, Tomokatsu ^a   Miyazaki, Takuro ^a   Li, Bo ^b   Miyazaki, Akira ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b First Affiliated Hospital of Luzhou Medical College   (China)

Author keywords

Hepatic stellate cells; Hic 5; Liver fibrosis; Smad2; Smad7; Tgfb1i1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CARBON TETRACHLORIDE; COLLAGEN; HYDROGEN PEROXIDE INDUCIBLE CLONE 5 PROTEIN; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; LIM PROTEIN; SMAD2 PROTEIN, MOUSE; SMAD7 PROTEIN, MOUSE; TGFB1I1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CLINICAL ARTICLE; CONTROLLED STUDY; FIBROGENESIS; HIC 5 DEFICIENCY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER; LIVER FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; DEFICIENCY; HEPATIC STELLATE CELL; LIVER CIRRHOSIS; METABOLISM; PHYSIOLOGY;

ACTINS; ANIMALS; CARBON TETRACHLORIDE; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; HEPATIC STELLATE CELLS; HUMANS; LIM DOMAIN PROTEINS; LIVER CIRRHOSIS; MICE; MICE, INBRED C57BL; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84949238886     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.08.026     Document Type: Article

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