메뉴 건너뛰기




Volumn 51, Issue 10, 2016, Pages 971-984

Carcinoma of the colon and rectum with deregulation of insulin-like growth factor 2 signaling: clinical and molecular implications

Author keywords

AKT1; Colon cancer; IGF2; Imprinting; Wnt5a

Indexed keywords

BRCA2 PROTEIN; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 6; CYCLIN DEPENDENT KINASE 1; SOMATOMEDIN B; TRICIRIBINE; WNT5A PROTEIN; AKT1 PROTEIN, HUMAN; CDK1 PROTEIN, HUMAN; CEACAM6 PROTEIN, HUMAN; CELL ADHESION MOLECULE; CYCLIN DEPENDENT KINASE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IGF1R PROTEIN, HUMAN; IGF2 PROTEIN, HUMAN; IMP3 PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; PROTEIN KINASE B; PROTEIN P21; RNA BINDING PROTEIN; SOMATOMEDIN RECEPTOR; WNT5A PROTEIN, HUMAN;

EID: 84961217548     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-016-1181-5     Document Type: Article
Times cited : (22)

References (45)
  • 1
    • 0033804122 scopus 로고    scopus 로고
    • Mechanisms of genomic imprinting
    • COI: 1:CAS:528:DC%2BD3cXnsVCgsrY%3D, PID: 10986038
    • Pfeifer K. Mechanisms of genomic imprinting. Am J Hum Genet. 2000;67(4):777–87.
    • (2000) Am J Hum Genet , vol.67 , Issue.4 , pp. 777-787
    • Pfeifer, K.1
  • 2
    • 29244447111 scopus 로고    scopus 로고
    • Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk
    • COI: 1:CAS:528:DC%2BD2MXhtlWiurfK, PID: 16357124
    • Kaneda A, Feinberg AP. Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk. Cancer Res. 2005;65(24):11236–40.
    • (2005) Cancer Res , vol.65 , Issue.24 , pp. 11236-11240
    • Kaneda, A.1    Feinberg, A.P.2
  • 3
    • 13644262798 scopus 로고    scopus 로고
    • Insulin-like growth factor ligands, receptors, and binding proteins in cancer
    • COI: 1:CAS:528:DC%2BD2MXhsFOhu7k%3D, PID: 15641016
    • Foulstone E, Prince S, Zaccheo O, et al. Insulin-like growth factor ligands, receptors, and binding proteins in cancer. J Pathol. 2005;205(2):145–53.
    • (2005) J Pathol , vol.205 , Issue.2 , pp. 145-153
    • Foulstone, E.1    Prince, S.2    Zaccheo, O.3
  • 4
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • COI: 1:CAS:528:DC%2BD38XkvFKltLs%3D, PID: 12094235, Epub 2002/07/03
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2(7):489–501 Epub 2002/07/03.
    • (2002) Nat Rev Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 5
    • 0037112364 scopus 로고    scopus 로고
    • Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2
    • COI: 1:CAS:528:DC%2BD38XovFOlu78%3D, PID: 12438232
    • Cui H, Onyango P, Brandenburg S, et al. Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. Cancer Res. 2002;62(22):6442–6.
    • (2002) Cancer Res , vol.62 , Issue.22 , pp. 6442-6446
    • Cui, H.1    Onyango, P.2    Brandenburg, S.3
  • 6
    • 0027172683 scopus 로고
    • Relaxation of imprinted genes in human cancer
    • COI: 1:CAS:528:DyaK3sXisFans7c%3D, PID: 8385745
    • Rainier S, Johnson LA, Dobry CJ, et al. Relaxation of imprinted genes in human cancer. Nature. 1993;362(6422):747–9.
    • (1993) Nature , vol.362 , Issue.6422 , pp. 747-749
    • Rainier, S.1    Johnson, L.A.2    Dobry, C.J.3
  • 7
    • 0027285258 scopus 로고
    • Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms’ tumour
    • COI: 1:CAS:528:DyaK3sXisFansL4%3D, PID: 8097018
    • Ogawa O, Eccles MR, Szeto J, et al. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms’ tumour. Nature. 1993;362(6422):749–51.
    • (1993) Nature , vol.362 , Issue.6422 , pp. 749-751
    • Ogawa, O.1    Eccles, M.R.2    Szeto, J.3
  • 8
    • 0028229910 scopus 로고
    • Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma
    • COI: 1:CAS:528:DyaK2cXltlWhsLw%3D, PID: 8040287
    • Zhan S, Shapiro DN, Helman LJ. Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. J Clin Investig. 1994;94(1):445–8.
    • (1994) J Clin Investig , vol.94 , Issue.1 , pp. 445-448
    • Zhan, S.1    Shapiro, D.N.2    Helman, L.J.3
  • 9
    • 0031761362 scopus 로고    scopus 로고
    • Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability
    • COI: 1:CAS:528:DyaK1cXntlamtLw%3D, PID: 9809551
    • Cui H, Horon IL, Ohlsson R, et al. Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability. Nat Med. 1998;4(11):1276–80.
    • (1998) Nat Med , vol.4 , Issue.11 , pp. 1276-1280
    • Cui, H.1    Horon, I.L.2    Ohlsson, R.3
  • 10
    • 0028880765 scopus 로고
    • Concordant loss of imprinting of the human insulin-like growth factor II gene promoters in cancer
    • COI: 1:CAS:528:DyaK2MXps1aiu7o%3D, PID: 7499276
    • Zhan S, Shapiro D, Zhan S, et al. Concordant loss of imprinting of the human insulin-like growth factor II gene promoters in cancer. J Biol Chem. 1995;270(47):27983–6.
    • (1995) J Biol Chem , vol.270 , Issue.47 , pp. 27983-27986
    • Zhan, S.1    Shapiro, D.2    Zhan, S.3
  • 11
    • 0028885930 scopus 로고
    • The expression of the imprinted H19 and IGF-2 genes in human bladder carcinoma
    • COI: 1:CAS:528:DyaK2MXovVyns7s%3D, PID: 7589512
    • Elkin M, Shevelev A, Schulze E, et al. The expression of the imprinted H19 and IGF-2 genes in human bladder carcinoma. FEBS Lett. 1995;374(1):57–61.
    • (1995) FEBS Lett , vol.374 , Issue.1 , pp. 57-61
    • Elkin, M.1    Shevelev, A.2    Schulze, E.3
  • 12
    • 0032080161 scopus 로고    scopus 로고
    • Loss of imprinting in disease progression in chronic myelogenous leukemia
    • COI: 1:CAS:528:DyaK1cXislCgu78%3D, PID: 9558368
    • Randhawa GS, Cui H, Barletta JA, et al. Loss of imprinting in disease progression in chronic myelogenous leukemia. Blood. 1998;91(9):3144–7.
    • (1998) Blood , vol.91 , Issue.9 , pp. 3144-3147
    • Randhawa, G.S.1    Cui, H.2    Barletta, J.A.3
  • 13
    • 0037436509 scopus 로고    scopus 로고
    • Loss of IGF2 imprinting: a potential marker of colorectal cancer risk
    • COI: 1:CAS:528:DC%2BD3sXitVSjtLw%3D, PID: 12637750
    • Cui H, Cruz-Correa M, Giardiello FM, et al. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science. 2003;299(5613):1753–5.
    • (2003) Science , vol.299 , Issue.5613 , pp. 1753-1755
    • Cui, H.1    Cruz-Correa, M.2    Giardiello, F.M.3
  • 14
    • 44449133319 scopus 로고    scopus 로고
    • PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations
    • COI: 1:CAS:528:DC%2BD1cXoslWgtLc%3D, PID: 18516290
    • Nosho K, Kawasaki T, Ohnishi M, et al. PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations. Neoplasia. 2008;10(6):534–41.
    • (2008) Neoplasia. , vol.10 , Issue.6 , pp. 534-541
    • Nosho, K.1    Kawasaki, T.2    Ohnishi, M.3
  • 15
    • 0037083484 scopus 로고    scopus 로고
    • Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors
    • COI: 1:CAS:528:DC%2BD38XitFOqur8%3D, PID: 11844828
    • Lindor NM, Burgart LJ, Leontovich O, et al. Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J clin oncol. 2002;20(4):1043–8.
    • (2002) J clin oncol , vol.20 , Issue.4 , pp. 1043-1048
    • Lindor, N.M.1    Burgart, L.J.2    Leontovich, O.3
  • 16
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
    • COI: 1:CAS:528:DC%2BD2MXht1ShtrnO, PID: 16199517, Epub 2005/10/04
    • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005;102(43):15545–50 Epub 2005/10/04.
    • (2005) Proc Natl Acad Sci USA. , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 17
    • 84891375329 scopus 로고    scopus 로고
    • Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer
    • PID: 23781309, Epub 2013/06/20
    • Belharazem D, Kirchner M, Geissler F, et al. Relaxed imprinting of IGF2 in peripheral blood cells of patients with a history of prostate cancer. Endocrine connections. 2012;1(2):87–94 Epub 2013/06/20.
    • (2012) Endocrine connections. , vol.1 , Issue.2 , pp. 87-94
    • Belharazem, D.1    Kirchner, M.2    Geissler, F.3
  • 18
    • 57749111001 scopus 로고    scopus 로고
    • ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells
    • COI: 1:CAS:528:DC%2BD1cXhsV2iurnL, PID: 19074849, Epub 2008/12/17
    • Lee SH, Bahn JH, Choi CK, et al. ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells. Mol Cancer Ther. 2008;7(12):3739–50 Epub 2008/12/17.
    • (2008) Mol Cancer Ther , vol.7 , Issue.12 , pp. 3739-3750
    • Lee, S.H.1    Bahn, J.H.2    Choi, C.K.3
  • 19
    • 27644525709 scopus 로고    scopus 로고
    • Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1
    • COI: 1:CAS:528:DC%2BD2MXhtFWhtLnN, PID: 16227405, Epub 2005/10/18
    • Moon Y, Bottone FG Jr, McEntee MF, et al. Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1. Mol Cancer Ther. 2005;4(10):1551–8 Epub 2005/10/18.
    • (2005) Mol Cancer Ther , vol.4 , Issue.10 , pp. 1551-1558
    • Moon, Y.1    Bottone, F.G.2    McEntee, M.F.3
  • 20
    • 0035895208 scopus 로고    scopus 로고
    • Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer
    • COI: 1:CAS:528:DC%2BD3MXnslKnsg%3D%3D, PID: 11120891
    • Nakagawa H, Chadwick RB, Peltomaki P, et al. Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer. Proc Natl Acad Sci USA. 2001;98(2):591–6.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.2 , pp. 591-596
    • Nakagawa, H.1    Chadwick, R.B.2    Peltomaki, P.3
  • 21
    • 0037385522 scopus 로고    scopus 로고
    • Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer
    • COI: 1:CAS:528:DC%2BD3sXivFClu7o%3D, PID: 12554765
    • Cui X, Zhang P, Deng W, et al. Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer. Mol Endocrinol. 2003;17(4):575–88.
    • (2003) Mol Endocrinol , vol.17 , Issue.4 , pp. 575-588
    • Cui, X.1    Zhang, P.2    Deng, W.3
  • 22
    • 11144356102 scopus 로고    scopus 로고
    • Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition
    • COI: 1:CAS:528:DC%2BD2cXkt1KrsLY%3D, PID: 15057734
    • Cruz-Correa M, Cui H, Giardiello FM, et al. Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology. 2004;126(4):964–70.
    • (2004) Gastroenterology , vol.126 , Issue.4 , pp. 964-970
    • Cruz-Correa, M.1    Cui, H.2    Giardiello, F.M.3
  • 23
    • 49649112211 scopus 로고    scopus 로고
    • Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer
    • COI: 1:CAS:528:DC%2BD1cXpvFyntLc%3D, PID: 18541649
    • Ito Y, Koessler T, Ibrahim AE, et al. Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. Hum Mol Genet. 2008;17(17):2633–43.
    • (2008) Hum Mol Genet , vol.17 , Issue.17 , pp. 2633-2643
    • Ito, Y.1    Koessler, T.2    Ibrahim, A.E.3
  • 24
    • 77954435392 scopus 로고    scopus 로고
    • Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer
    • COI: 1:CAS:528:DC%2BC3cXmslSntLs%3D, PID: 19957330
    • Cheng YW, Idrees K, Shattock R, et al. Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer. International journal of cancer Journal international du cancer. 2010;127(3):568–77.
    • (2010) International journal of cancer Journal international du cancer. , vol.127 , Issue.3 , pp. 568-577
    • Cheng, Y.W.1    Idrees, K.2    Shattock, R.3
  • 25
    • 48949097375 scopus 로고    scopus 로고
    • Genetic alterations in colorectal cancers with demethylation of insulin-like growth factor II
    • COI: 1:CAS:528:DC%2BD1cXhtVSjur7M, PID: 18619647
    • Ohta M, Sugimoto T, Seto M, et al. Genetic alterations in colorectal cancers with demethylation of insulin-like growth factor II. Hum Pathol. 2008;39(9):1301–8.
    • (2008) Hum Pathol , vol.39 , Issue.9 , pp. 1301-1308
    • Ohta, M.1    Sugimoto, T.2    Seto, M.3
  • 26
    • 33646530084 scopus 로고    scopus 로고
    • Clinicopathological characteristics of colorectal cancers with loss of imprinting of insulin-like growth factor 2
    • COI: 1:CAS:528:DC%2BD28Xkslyjtrc%3D, PID: 16432831
    • Sasaki J, Konishi F, Kawamura YJ, et al. Clinicopathological characteristics of colorectal cancers with loss of imprinting of insulin-like growth factor 2. Int J Cancer. 2006;119(1):80–3.
    • (2006) Int J Cancer. , vol.119 , Issue.1 , pp. 80-83
    • Sasaki, J.1    Konishi, F.2    Kawamura, Y.J.3
  • 27
    • 33746446922 scopus 로고    scopus 로고
    • Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection
    • COI: 1:CAS:528:DC%2BD28Xjs1KisLo%3D, PID: 16525660
    • Maenaka S, Hikichi T, Imai MA, et al. Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection. Oncol Rep. 2006;15(4):791–5.
    • (2006) Oncol Rep , vol.15 , Issue.4 , pp. 791-795
    • Maenaka, S.1    Hikichi, T.2    Imai, M.A.3
  • 28
    • 0034242382 scopus 로고    scopus 로고
    • Multipoint imprinting analysis in sporadic colorectal cancers with and without microsatellite instability
    • COI: 1:CAS:528:DC%2BD3cXls1Klurc%3D, PID: 10891541
    • Nishihara S, Hayashida T, Mitsuya K, et al. Multipoint imprinting analysis in sporadic colorectal cancers with and without microsatellite instability. Int J Oncol. 2000;17(2):317–22.
    • (2000) Int J Oncol , vol.17 , Issue.2 , pp. 317-322
    • Nishihara, S.1    Hayashida, T.2    Mitsuya, K.3
  • 29
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • COI: 1:CAS:528:DC%2BD28XmtFyqsr8%3D, PID: 16804544
    • Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet. 2006;38(7):787–93.
    • (2006) Nat Genet , vol.38 , Issue.7 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3
  • 30
    • 33745500432 scopus 로고    scopus 로고
    • CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies
    • COI: 1:CAS:528:DC%2BD28XntF2mu7w%3D, PID: 16407376
    • Ogino S, Cantor M, Kawasaki T, et al. CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies. Gut. 2006;55(7):1000–6.
    • (2006) Gut , vol.55 , Issue.7 , pp. 1000-1006
    • Ogino, S.1    Cantor, M.2    Kawasaki, T.3
  • 31
    • 84906935203 scopus 로고    scopus 로고
    • CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer
    • COI: 1:CAS:528:DC%2BC2cXht1Squ7nL, PID: 24859205
    • Shiovitz S, Bertagnolli MM, Renfro LA, et al. CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer. Gastroenterology. 2014;147(3):637–45.
    • (2014) Gastroenterology , vol.147 , Issue.3 , pp. 637-645
    • Shiovitz, S.1    Bertagnolli, M.M.2    Renfro, L.A.3
  • 32
    • 84905833580 scopus 로고    scopus 로고
    • IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions
    • COI: 1:CAS:528:DC%2BC2cXhvVaqtbrP, PID: 25110432
    • Naito T, Nosho K, Ito M, et al. IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions. World J Gastroenterol. 2014;20(29):10050–61.
    • (2014) World J Gastroenterol , vol.20 , Issue.29 , pp. 10050-10061
    • Naito, T.1    Nosho, K.2    Ito, M.3
  • 33
    • 78649693873 scopus 로고    scopus 로고
    • Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis
    • COI: 1:CAS:528:DC%2BC3cXhsFaktrvO, PID: 20682317
    • Baba Y, Nosho K, Shima K, et al. Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis. Gastroenterology. 2010;139(6):1855–64.
    • (2010) Gastroenterology , vol.139 , Issue.6 , pp. 1855-1864
    • Baba, Y.1    Nosho, K.2    Shima, K.3
  • 34
    • 84863922124 scopus 로고    scopus 로고
    • N. Comprehensive molecular characterization of human colon and rectal cancer
    • Cancer Genome Atlas. N. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012;487(7407):330–7.
    • (2012) Nature , vol.487 , Issue.7407 , pp. 330-337
    • Cancer Genome Atlas1
  • 35
    • 84904066077 scopus 로고    scopus 로고
    • Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
    • COI: 1:CAS:528:DC%2BC2cXos1arsr0%3D, PID: 24859528
    • Li X, Nadauld L, Ootani A, et al. Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture. Nat Med. 2014;20(7):769–77.
    • (2014) Nat Med , vol.20 , Issue.7 , pp. 769-777
    • Li, X.1    Nadauld, L.2    Ootani, A.3
  • 36
    • 20144374299 scopus 로고    scopus 로고
    • Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice
    • COI: 1:CAS:528:DC%2BD2MXisVyiurg%3D, PID: 15731405
    • Sakatani T, Kaneda A, Iacobuzio-Donahue CA, et al. Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science. 2005;307(5717):1976–8.
    • (2005) Science , vol.307 , Issue.5717 , pp. 1976-1978
    • Sakatani, T.1    Kaneda, A.2    Iacobuzio-Donahue, C.A.3
  • 37
    • 33644506750 scopus 로고    scopus 로고
    • Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting
    • COI: 1:CAS:528:DC%2BD28XhsFamur8%3D, PID: 16488992
    • Harper J, Burns JL, Foulstone EJ, et al. Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting. Cancer Res. 2006;66(4):1940–8.
    • (2006) Cancer Res , vol.66 , Issue.4 , pp. 1940-1948
    • Harper, J.1    Burns, J.L.2    Foulstone, E.J.3
  • 38
    • 38049170553 scopus 로고    scopus 로고
    • Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk
    • COI: 1:CAS:528:DC%2BD1cXktlKlsA%3D%3D, PID: 18087038
    • Kaneda A, Wang CJ, Cheong R, et al. Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk. Proc Natl Acad Sci USA. 2007;104(52):20926–31.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.52 , pp. 20926-20931
    • Kaneda, A.1    Wang, C.J.2    Cheong, R.3
  • 39
    • 85028194673 scopus 로고    scopus 로고
    • The stem cell transcription factor ZFP57 induces IGF2 expression to promote anchorage-independent growth in cancer cells
    • COI: 1:CAS:528:DC%2BC2cXht12js7w%3D, PID: 24469060
    • Tada Y, Yamaguchi Y, Kinjo T, et al. The stem cell transcription factor ZFP57 induces IGF2 expression to promote anchorage-independent growth in cancer cells. Oncogene. 2015;34(6):752–60.
    • (2015) Oncogene , vol.34 , Issue.6 , pp. 752-760
    • Tada, Y.1    Yamaguchi, Y.2    Kinjo, T.3
  • 40
    • 0034652480 scopus 로고    scopus 로고
    • Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice
    • COI: 1:CAS:528:DC%2BD3cXhs1ShsLY%3D, PID: 10706126
    • Hassan AB, Howell JA. Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice. Cancer Res. 2000;60(4):1070–6.
    • (2000) Cancer Res , vol.60 , Issue.4 , pp. 1070-1076
    • Hassan, A.B.1    Howell, J.A.2
  • 41
    • 0035899466 scopus 로고    scopus 로고
    • IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition
    • COI: 1:CAS:528:DC%2BD3MXmtlCksrs%3D, PID: 11526479
    • Morali OG, Delmas V, Moore R, et al. IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition. Oncogene. 2001;20(36):4942–50.
    • (2001) Oncogene , vol.20 , Issue.36 , pp. 4942-4950
    • Morali, O.G.1    Delmas, V.2    Moore, R.3
  • 42
    • 84910066394 scopus 로고    scopus 로고
    • A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis
    • COI: 1:CAS:528:DC%2BC2cXhvV2msrbK, PID: 25417160
    • Gujral TS, Chan M, Peshkin L, et al. A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Cell. 2014;159(4):844–56.
    • (2014) Cell , vol.159 , Issue.4 , pp. 844-856
    • Gujral, T.S.1    Chan, M.2    Peshkin, L.3
  • 43
    • 84921614073 scopus 로고    scopus 로고
    • Insight into the role of wnt5a-induced signaling in normal and cancer cells
    • PID: 25619716
    • Endo M, Nishita M, Fujii M, et al. Insight into the role of wnt5a-induced signaling in normal and cancer cells. Int Rev Cell Mol Biol. 2015;314:117–48.
    • (2015) Int Rev Cell Mol Biol. , vol.314 , pp. 117-148
    • Endo, M.1    Nishita, M.2    Fujii, M.3
  • 44
    • 0036781505 scopus 로고    scopus 로고
    • The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer
    • COI: 1:CAS:528:DC%2BD38Xmt12qt7c%3D, PID: 12191639
    • Klenova EM, Morse HC 3rd, Ohlsson R, et al. The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. Semin Cancer Biol. 2002;12(5):399–414.
    • (2002) Semin Cancer Biol , vol.12 , Issue.5 , pp. 399-414
    • Klenova, E.M.1    Morse, H.C.2    Ohlsson, R.3
  • 45
    • 84882578291 scopus 로고    scopus 로고
    • Gene therapy for cancer through adenovirus vectormediated expression of the Ad5 early region gene 1A based on loss of IGF2 imprinting
    • COI: 1:CAS:528:DC%2BC3sXhs1agsLfL, PID: 23900345
    • Pan Y, He B, Lirong Z, et al. Gene therapy for cancer through adenovirus vectormediated expression of the Ad5 early region gene 1A based on loss of IGF2 imprinting. Oncol Rep. 2013;30(4):1814–22.
    • (2013) Oncol Rep , vol.30 , Issue.4 , pp. 1814-1822
    • Pan, Y.1    He, B.2    Lirong, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.