IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions

World Journal of Gastroenterology

Volumn , Issue 29, 2014, Pages 10050-10061

  Naito, Takafumi ^a   Nosho, Katsuhiko ^a   Ito, Miki ^a   Igarashi, Hisayoshi ^a   Mitsuhashi, Kei ^a   Yoshii, Shinji ^b   Aoki, Hironori ^c   Nomura, Masafumi ^c   Sukawa, Yasutaka ^d   Yamamoto, Eiichiro ^a   Adachi, Yasushi ^a   Takahashi, Hiroaki ^b   Hosokawa, Masao ^b   Fujita, Masahiro ^b   Takenouchi, Toshinao ^b   Maruyama, Reo ^a   Suzuki, Hiromu ^a   Baba, Yoshifumi ^e   Imai, Kohzoh ^f   Yamamoto, Hiroyuki ^g   Ogino, Shuji ^d   Shinomura, Yasuhisa ^a   more..

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIYUKAI SAPPORO HOSPITAL   (Japan)

^c TEINE KEIJINKAI HOSPITAL   (Japan)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e KUMAMOTO UNIVERSITY   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

^g ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

BRAF; Colon polyp; Colorectal neoplasia; Colorectum; Genome; Insulin like growth factor; Long interspersed nucleotide element 1; Microsatellite instability; Serrated pathway

Indexed keywords

B RAF KINASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PHOSPHATIDYLINOSITOL 4, 5 BISPHOSPHATE 3 KINASE; SOMATOMEDIN B; UNCLASSIFIED DRUG; BRAF PROTEIN, HUMAN; DNA METHYLTRANSFERASE; IGF2 PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; MGMT PROTEIN, HUMAN; MLH1 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3CA PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAS PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN; K RAS PROTEIN; PROTEIN MLH1;

ADULT; ARTICLE; BRAF GENE; CANCER SURVIVAL; COLORECTAL CANCER; COLORECTAL TUMOR; CPG ISLAND; DIFFERENTIALLY METHYLATED REGION; DNA EXTRACTION; DNA METHYLATION; DYSPLASIA; EPIGENETICS; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; GENOME ANALYSIS; GENOME IMPRINTING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LONG INTERSPERSED REPEAT; MALE; MGMT GENE; MICROSATELLITE INSTABILITY; MOLECULAR PATHOLOGY; ONCOGENE K RAS; PIK3CA GENE; PYROSEQUENCING; RECTUM ADENOMA; ADENOMA; AGED; CHEMISTRY; CHI SQUARE DISTRIBUTION; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PATHOLOGY; PHENOTYPE; PROGNOSIS; STATISTICAL MODEL; CLINICAL FEATURE; COLON POLYP; CONTROLLED STUDY; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR VOLUME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOMA; AGED; CHI-SQUARE DISTRIBUTION; COLORECTAL NEOPLASMS; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INSULIN-LIKE GROWTH FACTOR II; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MULTIVARIATE ANALYSIS; NUCLEAR PROTEINS; PHENOTYPE; PHOSPHATIDYLINOSITOL 3-KINASES; PROGNOSIS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 84905833580     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i29.10050     Document Type: Article

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