-
1
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981; 292: 154-156.
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
2
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 1981; 78: 7634-7638.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 7634-7638
-
-
Martin, G.R.1
-
3
-
-
0035189927
-
Embryo-derived stem cells: Of mice and men
-
Smith AG. Embryo-derived stem cells: Of mice and men. Annu Rev Cell Dev Biol 2001; 17: 435-462.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 435-462
-
-
Smith, A.G.1
-
4
-
-
33947308285
-
How is pluripotency determined and maintained?
-
Niwa H. How is pluripotency determined and maintained? Development 2007; 134: 635-646.
-
(2007)
Development
, vol.134
, pp. 635-646
-
-
Niwa, H.1
-
5
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998; 95: 379-391.
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
Niwa, H.4
Klewe-Nebenius, D.5
Chambers, I.6
-
6
-
-
0034028901
-
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
-
Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000; 24: 372-376.
-
(2000)
Nat Genet
, vol.24
, pp. 372-376
-
-
Niwa, H.1
Miyazaki, J.2
Smith, A.G.3
-
7
-
-
34249876564
-
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
-
Masui S, Nakatake Y, Toyooka Y, Shimosato D, Yagi R, Takahashi K et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 2007; 9: 625-635.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 625-635
-
-
Masui, S.1
Nakatake, Y.2
Toyooka, Y.3
Shimosato, D.4
Yagi, R.5
Takahashi, K.6
-
8
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003; 113: 643-655.
-
(2003)
Cell
, vol.113
, pp. 643-655
-
-
Chambers, I.1
Colby, D.2
Robertson, M.3
Nichols, J.4
Lee, S.5
Tweedie, S.6
-
9
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113: 631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
Takahashi, K.6
-
10
-
-
37549002155
-
Nanog safeguards pluripotency and mediates germline development
-
Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, Robertson M et al. Nanog safeguards pluripotency and mediates germline development. Nature 2007; 450: 1230-1234.
-
(2007)
Nature
, vol.450
, pp. 1230-1234
-
-
Chambers, I.1
Silva, J.2
Colby, D.3
Nichols, J.4
Nijmeijer, B.5
Robertson, M.6
-
11
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005; 122: 947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
Zucker, J.P.6
-
12
-
-
33645381936
-
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
-
Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, Chen X et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 2006; 38: 431-440.
-
(2006)
Nat Genet
, vol.38
, pp. 431-440
-
-
Loh, Y.H.1
Wu, Q.2
Chew, J.L.3
Vega, V.B.4
Zhang, W.5
Chen, X.6
-
13
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001; 414: 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
14
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40: 499-507.
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
-
15
-
-
0032127977
-
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
-
Niwa H, Burdon T, Chambers I, Smith A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev 1998; 12: 2048-2060.
-
(1998)
Genes Dev
, vol.12
, pp. 2048-2060
-
-
Niwa, H.1
Burdon, T.2
Chambers, I.3
Smith, A.4
-
16
-
-
0033517123
-
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
-
Matsuda T, Nakamura T, Nakao K, Arai T, Katsuki M, Heike T et al. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J 1999; 18: 4261-4269.
-
(1999)
EMBO J
, vol.18
, pp. 4261-4269
-
-
Matsuda, T.1
Nakamura, T.2
Nakao, K.3
Arai, T.4
Katsuki, M.5
Heike, T.6
-
17
-
-
1042302005
-
The STATs of cancer - New molecular targets come of age
-
Yu H, Jove R. The STATs of cancer - new molecular targets come of age. Nat Rev Cancer 2004; 4: 97-105.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
19
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004; 10: 55-63.
-
(2004)
Nat Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
20
-
-
33645097331
-
Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells
-
Ogawa K, Nishinakamura R, Iwamatsu Y, Shimosato D, Niwa H. Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells. Biochem Biophys Res Commun 2006; 343: 159-166.
-
(2006)
Biochem Biophys Res Commun
, vol.343
, pp. 159-166
-
-
Ogawa, K.1
Nishinakamura, R.2
Iwamatsu, Y.3
Shimosato, D.4
Niwa, H.5
-
21
-
-
33845996890
-
B-Catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells
-
Takao Y, Yokota T, Koide H. b-Catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells. Biochem Biophys Res Commun 2007; 353: 699-705.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 699-705
-
-
Takao, Y.1
Yokota, T.2
Koide, H.3
-
23
-
-
85042536902
-
Involvement of Gli proteins in undifferentiated state maintenance and proliferation of embryonic stem cells
-
Ueda A. Involvement of Gli proteins in undifferentiated state maintenance and proliferation of embryonic stem cells. J Juzen Med Soc 2012; 121: 38-46.
-
(2012)
J Juzen Med Soc
, vol.121
, pp. 38-46
-
-
Ueda, A.1
-
24
-
-
13844320397
-
Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation
-
Schoonjans K, Dubuquoy L, Mebis J, Fayard E, Wendling O, Haby C et al. Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation. Proc Natl Acad Sci USA 2005; 102: 2058-2062.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2058-2062
-
-
Schoonjans, K.1
Dubuquoy, L.2
Mebis, J.3
Fayard, E.4
Wendling, O.5
Haby, C.6
-
25
-
-
66149167315
-
Functional evidence that the self-renewal gene NANOG regulates human tumor development
-
Jeter CR, Badeaux M, Choy G, Chandra D, Patrawala L, Liu C et al. Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells 2009; 27: 993-1005.
-
(2009)
Stem Cells
, vol.27
, pp. 993-1005
-
-
Jeter, C.R.1
Badeaux, M.2
Choy, G.3
Chandra, D.4
Patrawala, L.5
Liu, C.6
-
26
-
-
53249098795
-
A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints
-
Li X, Ito M, Zhou F, Youngson N, Zuo X, Leder P et al. A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints. Dev Cell 2008; 15: 547-557.
-
(2008)
Dev Cell
, vol.15
, pp. 547-557
-
-
Li, X.1
Ito, M.2
Zhou, F.3
Youngson, N.4
Zuo, X.5
Leder, P.6
-
27
-
-
80555156105
-
In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions
-
Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S et al. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions. Mol Cell 2011; 44: 361-372.
-
(2011)
Mol Cell
, vol.44
, pp. 361-372
-
-
Quenneville, S.1
Verde, G.2
Corsinotti, A.3
Kapopoulou, A.4
Jakobsson, J.5
Offner, S.6
-
28
-
-
40749128979
-
IGF2: Epigenetic regulation and role in development and disease
-
Chao W, D'Amore PA. IGF2: epigenetic regulation and role in development and disease. Cytokine Growth Factor Rev 2008; 19: 111-120.
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 111-120
-
-
Chao, W.1
D'amore, P.A.2
-
29
-
-
56749184290
-
Insulin and insulin-like growth factor signalling in neoplasia
-
Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 2008; 8: 915-928.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 915-928
-
-
Pollak, M.1
-
30
-
-
17444417417
-
Identification of Zfp-57 as a downstream molecule of STAT3 and Oct-3/4 in embryonic stem cells
-
Akagi T, Usuda M, Matsuda T, Ko MS, Niwa H, Asano M et al. Identification of Zfp-57 as a downstream molecule of STAT3 and Oct-3/4 in embryonic stem cells. Biochem Biophys Res Commun 2005; 331: 23-30.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 23-30
-
-
Akagi, T.1
Usuda, M.2
Matsuda, T.3
Ko, M.S.4
Niwa, H.5
Asano, M.6
-
31
-
-
0028224764
-
A novel nuclear protein with zinc fingers down-regulated during early mammalian cell differentiation
-
Okazaki S, Tanase S, Choudhury BK, Setoyama K, Miura R, Ogawa M et al. A novel nuclear protein with zinc fingers down-regulated during early mammalian cell differentiation. J Biol Chem 1994; 269: 6900-6907.
-
(1994)
J Biol Chem
, vol.269
, pp. 6900-6907
-
-
Okazaki, S.1
Tanase, S.2
Choudhury, B.K.3
Setoyama, K.4
Miura, R.5
Ogawa, M.6
-
32
-
-
2942618258
-
Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system
-
Alonso MB, Zoidl G, Taveggia C, Bosse F, Zoidl C, Rahman M et al. Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system. J Biol Chem 2004; 279: 25653-25664.
-
(2004)
J Biol Chem
, vol.279
, pp. 25653-25664
-
-
Alonso, M.B.1
Zoidl, G.2
Taveggia, C.3
Bosse, F.4
Zoidl, C.5
Rahman, M.6
-
33
-
-
84862908822
-
Zinc finger protein ZFP57 requires its co-factor to recruit DNA methyltransferases and maintains DNA methylation imprint in embryonic stem cells via its transcriptional repression domain
-
Zuo X, Sheng J, Lau HT, McDonald CM, Andrade M, Cullen DE et al. Zinc finger protein ZFP57 requires its co-factor to recruit DNA methyltransferases and maintains DNA methylation imprint in embryonic stem cells via its transcriptional repression domain. J Biol Chem 2012; 287: 2107-2118.
-
(2012)
J Biol Chem
, vol.287
, pp. 2107-2118
-
-
Zuo, X.1
Sheng, J.2
Lau, H.T.3
McDonald, C.M.4
Andrade, M.5
Cullen, D.E.6
-
34
-
-
48349092985
-
Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57
-
Mackay DJ, Callaway JL, Marks SM, White HE, Acerini CL, Boonen SE et al. Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57. Nat Genet 2008; 40: 949-951.
-
(2008)
Nat Genet
, vol.40
, pp. 949-951
-
-
Mackay, D.J.1
Callaway, J.L.2
Marks, S.M.3
White, H.E.4
Acerini, C.L.5
Boonen, S.E.6
-
35
-
-
84877770767
-
Genetic and epigenetic mutations affect the DNA binding capability of human ZFP57 in transient neonatal diabetes type 1
-
Baglivo I, Esposito S, De Cesare L, Sparago A, Anvar Z, Riso V et al. Genetic and epigenetic mutations affect the DNA binding capability of human ZFP57 in transient neonatal diabetes type 1. FEBS Lett 2013; 587: 1474-1481.
-
(2013)
FEBS Lett
, vol.587
, pp. 1474-1481
-
-
Baglivo, I.1
Esposito, S.2
De Cesare, L.3
Sparago, A.4
Anvar, Z.5
Riso, V.6
-
38
-
-
2642595021
-
Correlation of patterns of anchorage- independent growth with in vivo behavior of cells from a murine fibrosarcoma
-
Cifone MA, Fidler IJ. Correlation of patterns of anchorage- independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proc Natl Acad Sci USA 1980; 77: 1039-1043.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 1039-1043
-
-
Cifone, M.A.1
Fidler, I.J.2
-
39
-
-
68349125561
-
Anchorageindependent cell growth signature identifies tumors with metastatic potential
-
Mori S, Chang JT, Andrechek ER, Matsumura N, Baba T, Yao G et al. Anchorageindependent cell growth signature identifies tumors with metastatic potential. Oncogene 2009; 28: 2796-2805.
-
(2009)
Oncogene
, vol.28
, pp. 2796-2805
-
-
Mori, S.1
Chang, J.T.2
Andrechek, E.R.3
Matsumura, N.4
Baba, T.5
Yao, G.6
-
40
-
-
33846874575
-
The role of the IGF system in cancer growth and metastasis: Overview and recent insights
-
Samani AA, Yakar S, LeRoith D, Brodt P. The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 2007; 28: 20-47.
-
(2007)
Endocr Rev
, vol.28
, pp. 20-47
-
-
Samani, A.A.1
Yakar, S.2
Leroith, D.3
Brodt, P.4
-
41
-
-
84876030984
-
Evidence that Igf2 down-regulation in postnatal tissues and upregulation in malignancies is driven by transcription factor E2f3
-
Lui JC, Baron J. Evidence that Igf2 down-regulation in postnatal tissues and upregulation in malignancies is driven by transcription factor E2f3. Proc Natl Acad Sci USA 2013; 110: 6181-6186.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6181-6186
-
-
Lui, J.C.1
Baron, J.2
-
42
-
-
26644444345
-
Global loss of imprinting leads to widespread tumorigenesis in adult mice
-
Holm TM, Jackson-Grusby L, Brambrink T, Yamada Y, Rideout WM, Jaenisch R. Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell 2005; 8: 275-285.
-
(2005)
Cancer Cell
, vol.8
, pp. 275-285
-
-
Holm, T.M.1
Jackson-Grusby, L.2
Brambrink, T.3
Yamada, Y.4
Rideout, W.M.5
Jaenisch, R.6
-
43
-
-
33846581497
-
Loss of imprinting and cancer
-
Jelinic P, Shaw P. Loss of imprinting and cancer. J Pathol 2007; 211: 261-268.
-
(2007)
J Pathol
, vol.211
, pp. 261-268
-
-
Jelinic, P.1
Shaw, P.2
-
45
-
-
40649106258
-
Non-coding RNAs in imprinted gene clusters
-
Royo H, Cavaillé J. Non-coding RNAs in imprinted gene clusters. Biol Cell 2008; 100: 149-166.
-
(2008)
Biol Cell
, vol.100
, pp. 149-166
-
-
Royo, H.1
Cavaillé, J.2
-
46
-
-
78651397147
-
Large non-coding RNAs: Missing links in cancer?
-
Huarte M, Rinn JL. Large non-coding RNAs: missing links in cancer? Hum Mol Genet 2010; 19: 152-161.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 152-161
-
-
Huarte, M.1
Rinn, J.L.2
-
48
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
49
-
-
0347694729
-
Involvement of Ras in extraembryonic endoderm differentiation of embryonic stem cells
-
Yoshida-Koide U, Matsuda T, Saikawa K, Nakanuma Y, Yokota T, Asashima M et al. Involvement of Ras in extraembryonic endoderm differentiation of embryonic stem cells. Biochem Biophys Res Commun 2004; 313: 475-481.
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 475-481
-
-
Yoshida-Koide, U.1
Matsuda, T.2
Saikawa, K.3
Nakanuma, Y.4
Yokota, T.5
Asashima, M.6
|