메뉴 건너뛰기




Volumn 16, Issue 3, 2016, Pages

MicroRNAs in Diabetic Nephropathy: From Biomarkers to Therapy

Author keywords

Biomarker; Diabetic nephropathy; Fibrosis; MicroRNA; Non coding RNA; Therapeutics

Indexed keywords

BIOLOGICAL MARKER; CIRCULATING MICRORNA; DOUBLE STRANDED RNA; MESSENGER RNA; MICRORNA; MICRORNA 122; MICRORNA 141; MICRORNA 155; MICRORNA 16; MICRORNA 192; MICRORNA 200; MICRORNA 200A; MICRORNA 200B; MICRORNA 200C; MICRORNA 21; MICRORNA 210; MICRORNA 29; MICRORNA 29A; MICRORNA 29B; MICRORNA 29C; MICRORNA 34A; MICRORNA 429; MICRORNA 744; MICRORNA 93; MICRORNA LET 7; MICRORNA LIN 4; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; GENETIC MARKER;

EID: 84960956976     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-016-0724-8     Document Type: Review
Times cited : (124)

References (58)
  • 1
  • 2
    • 84880511470 scopus 로고    scopus 로고
    • Chronic kidney disease: global dimension and perspectives
    • PID: 23727169
    • Jha V, Garcia-Garcia G, Iseki K, Li Z, Naicker S, Plattner B, et al. Chronic kidney disease: global dimension and perspectives. Lancet. 2013;382(9888):260–72. doi:10.1016/S0140-6736(13)60687-X.
    • (2013) Lancet , vol.382 , Issue.9888 , pp. 260-272
    • Jha, V.1    Garcia-Garcia, G.2    Iseki, K.3    Li, Z.4    Naicker, S.5    Plattner, B.6
  • 3
    • 0024463832 scopus 로고
    • Disparities in incidence of diabetic end-stage renal disease according to race and type of diabetes
    • COI: 1:STN:280:DyaK3c%2FhsV2rtQ%3D%3D, PID: 2797067
    • Cowie CC, Port FK, Wolfe RA, Savage PJ, Moll PP, Hawthorne VM. Disparities in incidence of diabetic end-stage renal disease according to race and type of diabetes. N Engl J Med. 1989;321(16):1074–9. doi:10.1056/NEJM198910193211603.
    • (1989) N Engl J Med , vol.321 , Issue.16 , pp. 1074-1079
    • Cowie, C.C.1    Port, F.K.2    Wolfe, R.A.3    Savage, P.J.4    Moll, P.P.5    Hawthorne, V.M.6
  • 4
    • 84939624622 scopus 로고    scopus 로고
    • Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes
    • PID: 26209735
    • Regele F, Jelencsics K, Shiffman D, Pare G, McQueen MJ, Mann JF, et al. Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes. Nephrol Dial Transplant. 2015;30 Suppl 4:iv26–34. doi:10.1093/ndt/gfv087.
    • (2015) Nephrol Dial Transplant , vol.30 Suppl 4 , pp. iv26-iv34
    • Regele, F.1    Jelencsics, K.2    Shiffman, D.3    Pare, G.4    McQueen, M.J.5    Mann, J.F.6
  • 5
    • 0025938891 scopus 로고
    • Advanced glycosylation end products in patients with diabetic nephropathy
    • COI: 1:STN:280:DyaK3Mzkt1OisQ%3D%3D, PID: 1875967
    • Makita Z, Radoff S, Rayfield EJ, Yang Z, Skolnik E, Delaney V, et al. Advanced glycosylation end products in patients with diabetic nephropathy. N Engl J Med. 1991;325(12):836–42. doi:10.1056/NEJM199109193251202.
    • (1991) N Engl J Med , vol.325 , Issue.12 , pp. 836-842
    • Makita, Z.1    Radoff, S.2    Rayfield, E.J.3    Yang, Z.4    Skolnik, E.5    Delaney, V.6
  • 6
    • 10644259663 scopus 로고    scopus 로고
    • From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines
    • COI: 1:CAS:528:DC%2BD2MXjslWntw%3D%3D, PID: 15583025
    • Schrijvers BF, De Vriese AS, Flyvbjerg A. From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines. Endocr Rev. 2004;25(6):971–1010. doi:10.1210/er.2003-0018.
    • (2004) Endocr Rev , vol.25 , Issue.6 , pp. 971-1010
    • Schrijvers, B.F.1    De Vriese, A.S.2    Flyvbjerg, A.3
  • 7
    • 79952740443 scopus 로고    scopus 로고
    • Podocytes as a target of insulin
    • COI: 1:CAS:528:DC%2BC3MXisVGntro%3D, PID: 21067503
    • Coward RJ, Saleem MA. Podocytes as a target of insulin. Curr Diabetes Rev. 2011;7(1):22–7.
    • (2011) Curr Diabetes Rev , vol.7 , Issue.1 , pp. 22-27
    • Coward, R.J.1    Saleem, M.A.2
  • 8
    • 84873021479 scopus 로고    scopus 로고
    • Diabetic nephropathy and extracellular matrix
    • COI: 1:CAS:528:DC%2BC3sXpvVKkuro%3D, PID: 23103723
    • Kolset SO, Reinholt FP, Jenssen T. Diabetic nephropathy and extracellular matrix. J Histochem Cytochem. 2012;60(12):976–86. doi:10.1369/0022155412465073.
    • (2012) J Histochem Cytochem , vol.60 , Issue.12 , pp. 976-986
    • Kolset, S.O.1    Reinholt, F.P.2    Jenssen, T.3
  • 9
    • 33748291391 scopus 로고    scopus 로고
    • Tubulointerstitial damage and progression of renal failure
    • COI: 1:CAS:528:DC%2BD2MXhtlWqtr7I, PID: 16336583
    • Rodriguez-Iturbe B, Johnson RJ, Herrera-Acosta J. Tubulointerstitial damage and progression of renal failure. Kidney Int Suppl. 2005;99:S82–6. doi:10.1111/j.1523-1755.2005.09915.x.
    • (2005) Kidney Int Suppl , vol.99 , pp. S82-S86
    • Rodriguez-Iturbe, B.1    Johnson, R.J.2    Herrera-Acosta, J.3
  • 10
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • COI: 1:CAS:528:DyaK2cXpslGqtA%3D%3D, PID: 8252621
    • Lee RC, Feinbaum RL, Ambros C. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993;75(5):843–54.
    • (1993) Cell , vol.75 , Issue.5 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, C.3
  • 11
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
    • COI: 1:CAS:528:DC%2BD3cXhs1Ors74%3D, PID: 10706289
    • Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature. 2000;403(6772):901–6. doi:10.1038/35002607.
    • (2000) Nature , vol.403 , Issue.6772 , pp. 901-906
    • Reinhart, B.J.1    Slack, F.J.2    Basson, M.3    Pasquinelli, A.E.4    Bettinger, J.C.5    Rougvie, A.E.6
  • 12
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • COI: 1:CAS:528:DC%2BD3cXotVaks70%3D, PID: 11081512
    • Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, et al. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature. 2000;408(6808):86–9. doi:10.1038/35040556.
    • (2000) Nature , vol.408 , Issue.6808 , pp. 86-89
    • Pasquinelli, A.E.1    Reinhart, B.J.2    Slack, F.3    Martindale, M.Q.4    Kuroda, M.I.5    Maller, B.6
  • 13
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • COI: 1:CAS:528:DC%2BD3MXotVChu70%3D, PID: 11679672
    • Lee RC, Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science. 2001;294(5543):862–4. doi:10.1126/science.1065329.
    • (2001) Science , vol.294 , Issue.5543 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 14
    • 33744520104 scopus 로고    scopus 로고
    • Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
    • COI: 1:CAS:528:DC%2BD28Xls1Shtr4%3D, PID: 16751099
    • Han J, Lee Y, Yeom KH, Nam JW, Heo I, Rhee JK, et al. Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell. 2006;125(5):887–901. doi:10.1016/j.cell.2006.03.043.
    • (2006) Cell , vol.125 , Issue.5 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Nam, J.W.4    Heo, I.5    Rhee, J.K.6
  • 15
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • COI: 1:CAS:528:DC%2BD2MXhtFaguw%3D%3D, PID: 15574589
    • Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 2004;18(24):3016–27. doi:10.1101/gad.1262504.
    • (2004) Genes Dev , vol.18 , Issue.24 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 16
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • COI: 1:CAS:528:DC%2BD2cXjt1Crsr0%3D, PID: 15105502
    • Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science. 2004;304(5670):594–6. doi:10.1126/science.1097434.
    • (2004) Science , vol.304 , Issue.5670 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 17
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • COI: 1:CAS:528:DC%2BD3sXjvVOl, PID: 12434020
    • Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99(24):15524–9. doi:10.1073/pnas.242606799.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.24 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 18
    • 27244434788 scopus 로고    scopus 로고
    • A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • COI: 1:CAS:528:DC%2BD2MXhtFKrtLbJ, PID: 16251535
    • Calin GA, Ferracin M, Cimmino A, Di Leva G, Shimizu M, Wojcik SE, et al. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med. 2005;353(17):1793–801. doi:10.1056/NEJMoa050995.
    • (2005) N Engl J Med , vol.353 , Issue.17 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3    Di Leva, G.4    Shimizu, M.5    Wojcik, S.E.6
  • 19
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissue-specific microRNAs from mouse
    • COI: 1:CAS:528:DC%2BD38XjsFygtb4%3D, PID: 12007417
    • Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T. Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002;12(9):735–9.
    • (2002) Curr Biol , vol.12 , Issue.9 , pp. 735-739
    • Lagos-Quintana, M.1    Rauhut, R.2    Yalcin, A.3    Meyer, J.4    Lendeckel, W.5    Tuschl, T.6
  • 20
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • COI: 1:CAS:528:DC%2BD2sXotV2hsLk%3D, PID: 17604727
    • Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell. 2007;129(7):1401–14. doi:10.1016/j.cell.2007.04.040.
    • (2007) Cell , vol.129 , Issue.7 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3    Sewer, A.4    Iovino, N.5    Aravin, A.6
  • 21
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • COI: 1:CAS:528:DC%2BD2sXmtVSmtb8%3D, PID: 17486113
    • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9(6):654–9. doi:10.1038/ncb1596.
    • (2007) Nat Cell Biol , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 23
    • 43449102192 scopus 로고    scopus 로고
    • Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
    • PID: 18318758
    • Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, Pulford K, et al. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br J Haematol. 2008;141(5):672–5. doi:10.1111/j.1365-2141.2008.07077.x.
    • (2008) Br J Haematol , vol.141 , Issue.5 , pp. 672-675
    • Lawrie, C.H.1    Gal, S.2    Dunlop, H.M.3    Pushkaran, B.4    Liggins, A.P.5    Pulford, K.6
  • 24
    • 84869741959 scopus 로고    scopus 로고
    • Circulating microRNAs: new biomarkers in diagnosis, prognosis and treatment of cancer (review)
    • COI: 1:CAS:528:DC%2BC38XhvFShtr7N, PID: 23026890
    • Allegra A, Alonci A, Campo S, Penna G, Petrungaro A, Gerace D, et al. Circulating microRNAs: new biomarkers in diagnosis, prognosis and treatment of cancer (review). Int J Oncol. 2012;41(6):1897–912. doi:10.3892/ijo.2012.1647.
    • (2012) Int J Oncol , vol.41 , Issue.6 , pp. 1897-1912
    • Allegra, A.1    Alonci, A.2    Campo, S.3    Penna, G.4    Petrungaro, A.5    Gerace, D.6
  • 25
    • 79953202200 scopus 로고    scopus 로고
    • Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    • COI: 1:CAS:528:DC%2BC3MXktVCjsro%3D, PID: 21383194, This study provides data on factors stabilizing circulating miRNAs, and identifies discrete EVA- and NVA-miRNA populations
    • Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A. 2011;108(12):5003–8. doi:10.1073/pnas.1019055108. This study provides data on factors stabilizing circulating miRNAs, and identifies discrete EVA- and NVA-miRNA populations.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.12 , pp. 5003-5008
    • Arroyo, J.D.1    Chevillet, J.R.2    Kroh, E.M.3    Ruf, I.K.4    Pritchard, C.C.5    Gibson, D.F.6
  • 26
    • 80052381608 scopus 로고    scopus 로고
    • Characterization of extracellular circulating microRNA
    • COI: 1:CAS:528:DC%2BC3MXhtFehtr%2FE, PID: 21609964
    • Turchinovich A, Weiz L, Langheinz A, Burwinkel B. Characterization of extracellular circulating microRNA. Nucleic Acids Res. 2011;39(16):7223–33. doi:10.1093/nar/gkr254.
    • (2011) Nucleic Acids Res , vol.39 , Issue.16 , pp. 7223-7233
    • Turchinovich, A.1    Weiz, L.2    Langheinz, A.3    Burwinkel, B.4
  • 27
    • 84864393060 scopus 로고    scopus 로고
    • Analysis of urinary microRNAs in chronic kidney disease
    • COI: 1:CAS:528:DC%2BC38XhtVOjt7vO, PID: 22817751
    • Beltrami C, Clayton A, Phillips AO, Fraser DJ, Bowen T. Analysis of urinary microRNAs in chronic kidney disease. Biochem Soc Trans. 2012;40(4):875–9. doi:10.1042/BST20120090.
    • (2012) Biochem Soc Trans , vol.40 , Issue.4 , pp. 875-879
    • Beltrami, C.1    Clayton, A.2    Phillips, A.O.3    Fraser, D.J.4    Bowen, T.5
  • 28
    • 66549122028 scopus 로고    scopus 로고
    • Cell to cell signalling via exosomes through esRNA
    • PID: 19262134
    • Lotvall J, Valadi H. Cell to cell signalling via exosomes through esRNA. Cell Adh Migr. 2007;1(3):156–8.
    • (2007) Cell Adh Migr , vol.1 , Issue.3 , pp. 156-158
    • Lotvall, J.1    Valadi, H.2
  • 29
    • 78149409316 scopus 로고    scopus 로고
    • Export of microRNAs and microRNA-protective protein by mammalian cells
    • COI: 1:CAS:528:DC%2BC3cXhsVektrzE, PID: 20615901
    • Wang K, Zhang S, Weber J, Baxter D, Galas DJ. Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Res. 2010;38(20):7248–59. doi:10.1093/nar/gkq601.
    • (2010) Nucleic Acids Res , vol.38 , Issue.20 , pp. 7248-7259
    • Wang, K.1    Zhang, S.2    Weber, J.3    Baxter, D.4    Galas, D.J.5
  • 30
    • 79953301730 scopus 로고    scopus 로고
    • MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
    • COI: 1:CAS:528:DC%2BC3MXktFWjsb4%3D, PID: 21423178
    • Vickers KC, Palmisano BT, Shoucri BM, Shamburek RD, Remaley AT. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol. 2011;13(4):423–33. doi:10.1038/ncb2210.
    • (2011) Nat Cell Biol , vol.13 , Issue.4 , pp. 423-433
    • Vickers, K.C.1    Palmisano, B.T.2    Shoucri, B.M.3    Shamburek, R.D.4    Remaley, A.T.5
  • 31
    • 84860353677 scopus 로고    scopus 로고
    • Validation of the isolation and quantification of kidney enriched miRNAs for use as biomarkers
    • COI: 1:CAS:528:DC%2BC38Xmt1Shtr0%3D, PID: 22356305
    • Sharkey JW, Antoine DJ, Park BK. Validation of the isolation and quantification of kidney enriched miRNAs for use as biomarkers. Biomarkers. 2012;17(3):231–9. doi:10.3109/1354750X.2012.657246.
    • (2012) Biomarkers , vol.17 , Issue.3 , pp. 231-239
    • Sharkey, J.W.1    Antoine, D.J.2    Park, B.K.3
  • 32
    • 84867897248 scopus 로고    scopus 로고
    • Urinary miR-21, miR-29, and miR-93: novel biomarkers of fibrosis
    • COI: 1:CAS:528:DC%2BC38XhslGrurbI, PID: 23108026
    • Wang G, Kwan BC, Lai FM, Chow KM, Li PK, Szeto CC. Urinary miR-21, miR-29, and miR-93: novel biomarkers of fibrosis. Am J Nephrol. 2012;36(5):412–8. doi:10.1159/000343452.
    • (2012) Am J Nephrol , vol.36 , Issue.5 , pp. 412-418
    • Wang, G.1    Kwan, B.C.2    Lai, F.M.3    Chow, K.M.4    Li, P.K.5    Szeto, C.C.6
  • 33
    • 84983424584 scopus 로고    scopus 로고
    • Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein
    • Beltrami C, Clayton A, Newbury LJ, Corish C, Jenkins RH, Phillips AO, et al. Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA. 2015;1(2):151–65. doi:10.3390/ncrna1020151.
    • (2015) Non-Coding RNA , vol.1 , Issue.2 , pp. 151-165
    • Beltrami, C.1    Clayton, A.2    Newbury, L.J.3    Corish, C.4    Jenkins, R.H.5    Phillips, A.O.6
  • 34
    • 84872860732 scopus 로고    scopus 로고
    • Urinary microRNA profiling in the nephropathy of type 1 diabetes
    • COI: 1:CAS:528:DC%2BC3sXit1Chs70%3D, PID: 23358711
    • Argyropoulos C, Wang K, McClarty S, Huang D, Bernardo J, Ellis D, et al. Urinary microRNA profiling in the nephropathy of type 1 diabetes. PLoS One. 2013;8(1), e54662. doi:10.1371/journal.pone.0054662.
    • (2013) PLoS One , vol.8 , Issue.1
    • Argyropoulos, C.1    Wang, K.2    McClarty, S.3    Huang, D.4    Bernardo, J.5    Ellis, D.6
  • 35
    • 84857968441 scopus 로고    scopus 로고
    • The majority of microRNAs detectable in serum and saliva is concentrated in exosomes
    • COI: 1:CAS:528:DC%2BC38XktlSktrs%3D, PID: 22427800
    • Gallo A, Tandon M, Alevizos I, Illei GG. The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. PLoS One. 2012;7(3), e30679. doi:10.1371/journal.pone.0030679.
    • (2012) PLoS One , vol.7 , Issue.3
    • Gallo, A.1    Tandon, M.2    Alevizos, I.3    Illei, G.G.4
  • 36
    • 84907906605 scopus 로고    scopus 로고
    • Quantitative and stoichiometric analysis of the microRNA content of exosomes
    • COI: 1:CAS:528:DC%2BC2cXhs1Cht77O, PID: 25267620
    • Chevillet JR, Kang Q, Ruf IK, Briggs HA, Vojtech LN, Hughes SM, et al. Quantitative and stoichiometric analysis of the microRNA content of exosomes. Proc Natl Acad Sci U S A. 2014;111(41):14888–93. doi:10.1073/pnas.1408301111.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.41 , pp. 14888-14893
    • Chevillet, J.R.1    Kang, Q.2    Ruf, I.K.3    Briggs, H.A.4    Vojtech, L.N.5    Hughes, S.M.6
  • 37
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • COI: 1:CAS:528:DC%2BD1cXotVertbo%3D, PID: 18548003
    • Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature. 2008;454(7200):56–61. doi:10.1038/nature07086.
    • (2008) Nature , vol.454 , Issue.7200 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 38
    • 80053536529 scopus 로고    scopus 로고
    • Post-transcriptional regulation of transforming growth factor beta-1 by microRNA-744
    • COI: 1:CAS:528:DC%2BC3MXhtlOlt7bL, PID: 21991303
    • Martin J, Jenkins RH, Bennagi R, Krupa A, Phillips AO, Bowen T, et al. Post-transcriptional regulation of transforming growth factor beta-1 by microRNA-744. PLoS One. 2011;6(10), e25044. doi:10.1371/journal.pone.0025044.
    • (2011) PLoS One , vol.6 , Issue.10
    • Martin, J.1    Jenkins, R.H.2    Bennagi, R.3    Krupa, A.4    Phillips, A.O.5    Bowen, T.6
  • 39
    • 33847682663 scopus 로고    scopus 로고
    • MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
    • COI: 1:CAS:528:DC%2BD2sXjtVWltLo%3D, PID: 17360662
    • Kato M, Zhang J, Wang M, Lanting L, Yuan H, Rossi JJ, et al. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A. 2007;104(9):3432–7. doi:10.1073/pnas.0611192104.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.9 , pp. 3432-3437
    • Kato, M.1    Zhang, J.2    Wang, M.3    Lanting, L.4    Yuan, H.5    Rossi, J.J.6
  • 40
    • 77949892330 scopus 로고    scopus 로고
    • Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy
    • COI: 1:CAS:528:DC%2BC3cXjvFClurw%3D, PID: 20056746
    • Krupa A, Jenkins R, Luo DD, Lewis A, Phillips A, Fraser D. Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy. J Am Soc Nephrol. 2010;21(3):438–47. doi:10.1681/ASN.2009050530.
    • (2010) J Am Soc Nephrol , vol.21 , Issue.3 , pp. 438-447
    • Krupa, A.1    Jenkins, R.2    Luo, D.D.3    Lewis, A.4    Phillips, A.5    Fraser, D.6
  • 41
    • 77954274715 scopus 로고    scopus 로고
    • E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta
    • COI: 1:CAS:528:DC%2BC3cXpsVOlsLo%3D, PID: 20393144
    • Wang B, Herman-Edelstein M, Koh P, Burns W, Jandeleit-Dahm K, Watson A, et al. E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta. Diabetes. 2010;59(7):1794–802. doi:10.2337/db09-1736.
    • (2010) Diabetes , vol.59 , Issue.7 , pp. 1794-1802
    • Wang, B.1    Herman-Edelstein, M.2    Koh, P.3    Burns, W.4    Jandeleit-Dahm, K.5    Watson, A.6
  • 42
    • 84864379328 scopus 로고    scopus 로고
    • Pleiotropy of microRNA-192 in the kidney
    • COI: 1:CAS:528:DC%2BC38XhtVOjt7%2FM, PID: 22817730
    • Jenkins RH, Martin J, Phillips AO, Bowen T, Fraser DJ. Pleiotropy of microRNA-192 in the kidney. Biochem Soc Trans. 2012;40(4):762–7. doi:10.1042/BST20120085.
    • (2012) Biochem Soc Trans , vol.40 , Issue.4 , pp. 762-767
    • Jenkins, R.H.1    Martin, J.2    Phillips, A.O.3    Bowen, T.4    Fraser, D.J.5
  • 43
    • 84878269299 scopus 로고    scopus 로고
    • miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes
    • COI: 1:CAS:528:DC%2BC3sXit1eiurg%3D, PID: 23292313, This study describes overexpression and downregulation of miR-21 in disease models, and subsequent findings showing profibrotic and antifibrotic effects, respectively
    • Zhong X, Chung AC, Chen HY, Dong Y, Meng XM, Li R, et al. miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes. Diabetologia. 2013;56(3):663–74. doi:10.1007/s00125-012-2804-x. This study describes overexpression and downregulation of miR-21 in disease models, and subsequent findings showing profibrotic and antifibrotic effects, respectively.
    • (2013) Diabetologia , vol.56 , Issue.3 , pp. 663-674
    • Zhong, X.1    Chung, A.C.2    Chen, H.Y.3    Dong, Y.4    Meng, X.M.5    Li, R.6
  • 44
    • 84903266446 scopus 로고    scopus 로고
    • MicroRNA21 inhibits SMAD7 expression through a target sequence in the 3′ untranslated region and inhibits proliferation of renal tubular epithelial cells
    • COI: 1:CAS:528:DC%2BC2cXht1CqurzI, PID: 24913635
    • Lin L, Gan H, Zhang H, Tang W, Sun Y, Tang X, et al. MicroRNA21 inhibits SMAD7 expression through a target sequence in the 3′ untranslated region and inhibits proliferation of renal tubular epithelial cells. Mol Med Rep. 2014;10(2):707–12. doi:10.3892/mmr.2014.2312.
    • (2014) Mol Med Rep , vol.10 , Issue.2 , pp. 707-712
    • Lin, L.1    Gan, H.2    Zhang, H.3    Tang, W.4    Sun, Y.5    Tang, X.6
  • 45
    • 84942693250 scopus 로고    scopus 로고
    • Network-based approaches to understand the roles of miR-200 and other microRNAs in cancer
    • COI: 1:CAS:528:DC%2BC2MXhtV2is77K, PID: 26069247
    • Bracken CP, Khew-Goodall Y, Goodall GJ. Network-based approaches to understand the roles of miR-200 and other microRNAs in cancer. Cancer Res. 2015;75(13):2594–9. doi:10.1158/0008-5472.CAN-15-0287.
    • (2015) Cancer Res , vol.75 , Issue.13 , pp. 2594-2599
    • Bracken, C.P.1    Khew-Goodall, Y.2    Goodall, G.J.3
  • 46
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • COI: 1:CAS:528:DC%2BD1cXksVGktL4%3D, PID: 18381893
    • Park SM, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 2008;22(7):894–907. doi:10.1101/gad.1640608.
    • (2008) Genes Dev , vol.22 , Issue.7 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 47
    • 80052248898 scopus 로고    scopus 로고
    • A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells
    • COI: 1:CAS:528:DC%2BC3MXpsFGqsrc%3D, PID: 21389977
    • Kato M, Arce L, Wang M, Putta S, Lanting L, Natarajan R. A microRNA circuit mediates transforming growth factor-beta1 autoregulation in renal glomerular mesangial cells. Kidney Int. 2011;80(4):358–68. doi:10.1038/ki.2011.43.
    • (2011) Kidney Int , vol.80 , Issue.4 , pp. 358-368
    • Kato, M.1    Arce, L.2    Wang, M.3    Putta, S.4    Lanting, L.5    Natarajan, R.6
  • 48
    • 84921677205 scopus 로고    scopus 로고
    • MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction
    • COI: 1:CAS:528:DC%2BC2cXhsFOnu7rO, PID: 24578127
    • Lin CL, Lee PH, Hsu YC, Lei CC, Ko JY, Chuang PC, et al. MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction. J Am Soc Nephrol. 2014;25(8):1698–709. doi:10.1681/ASN.2013050527.
    • (2014) J Am Soc Nephrol , vol.25 , Issue.8 , pp. 1698-1709
    • Lin, C.L.1    Lee, P.H.2    Hsu, Y.C.3    Lei, C.C.4    Ko, J.Y.5    Chuang, P.C.6
  • 49
    • 69949087531 scopus 로고    scopus 로고
    • MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
    • PID: 19714243
    • Ji Q, Hao X, Zhang M, Tang W, Yang M, Li L, et al. MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One. 2009;4(8), e6816. doi:10.1371/journal.pone.0006816.
    • (2009) PLoS One , vol.4 , Issue.8
    • Ji, Q.1    Hao, X.2    Zhang, M.3    Tang, W.4    Yang, M.5    Li, L.6
  • 50
    • 77955022405 scopus 로고    scopus 로고
    • Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
    • COI: 1:CAS:528:DC%2BC3cXovVanu7s%3D, PID: 20570894
    • Wiggins JF, Ruffino L, Kelnar K, Omotola M, Patrawala L, Brown D, et al. Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res. 2010;70(14):5923–30. doi:10.1158/0008-5472.CAN-10-0655.
    • (2010) Cancer Res , vol.70 , Issue.14 , pp. 5923-5930
    • Wiggins, J.F.1    Ruffino, L.2    Kelnar, K.3    Omotola, M.4    Patrawala, L.5    Brown, D.6
  • 51
    • 74249112787 scopus 로고    scopus 로고
    • Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
    • COI: 1:CAS:528:DC%2BC3cXht1egsA%3D%3D, PID: 19965718
    • Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, Munk ME, et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science. 2010;327(5962):198–201. doi:10.1126/science.1178178.
    • (2010) Science , vol.327 , Issue.5962 , pp. 198-201
    • Lanford, R.E.1    Hildebrandt-Eriksen, E.S.2    Petri, A.3    Persson, R.4    Lindow, M.5    Munk, M.E.6
  • 52
    • 84857979740 scopus 로고    scopus 로고
    • Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy
    • COI: 1:CAS:528:DC%2BC38Xlt1Omtro%3D, PID: 22223877
    • Putta S, Lanting L, Sun G, Lawson G, Kato M, Natarajan R. Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy. J Am Soc Nephrol. 2012;23(3):458–69. doi:10.1681/ASN.2011050485.
    • (2012) J Am Soc Nephrol , vol.23 , Issue.3 , pp. 458-469
    • Putta, S.1    Lanting, L.2    Sun, G.3    Lawson, G.4    Kato, M.5    Natarajan, R.6
  • 53
    • 84945444690 scopus 로고    scopus 로고
    • MicroRNAs in diabetic nephropathy: functions, biomarkers, and therapeutic targets
    • PID: 25877817
    • Kato M, Natarajan R. MicroRNAs in diabetic nephropathy: functions, biomarkers, and therapeutic targets. Ann N Y Acad Sci. 2015. doi:10.1111/nyas.12758.
    • (2015) Ann N Y Acad Sci
    • Kato, M.1    Natarajan, R.2
  • 54
    • 79953215711 scopus 로고    scopus 로고
    • MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy
    • COI: 1:CAS:528:DC%2BC3MXjslKgtb4%3D, PID: 21310958
    • Long J, Wang Y, Wang W, Chang BH, Danesh FR. MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. J Biol Chem. 2011;286(13):11837–48. doi:10.1074/jbc.M110.194969.
    • (2011) J Biol Chem , vol.286 , Issue.13 , pp. 11837-11848
    • Long, J.1    Wang, Y.2    Wang, W.3    Chang, B.H.4    Danesh, F.R.5
  • 55
    • 80054771082 scopus 로고    scopus 로고
    • Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192
    • COI: 1:CAS:528:DC%2BC3MXht1yhtLnN, PID: 21984124
    • Sun L, Zhang D, Liu F, Xiang X, Ling G, Xiao L, et al. Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192. J Pathol. 2011;225(3):364–77. doi:10.1002/path.2961.
    • (2011) J Pathol , vol.225 , Issue.3 , pp. 364-377
    • Sun, L.1    Zhang, D.2    Liu, F.3    Xiang, X.4    Ling, G.5    Xiao, L.6
  • 56
    • 78649447847 scopus 로고    scopus 로고
    • Targeted renal therapies through microbubbles and ultrasound
    • COI: 1:CAS:528:DC%2BC3cXhsVyhtr3E, PID: 20946925
    • Deelman LE, Declèves AE, Rychak JJ, Sharma K. Targeted renal therapies through microbubbles and ultrasound. Adv Drug Deliv Rev. 2010;62(14):1369–77. doi:10.1016/j.addr.2010.10.002.
    • (2010) Adv Drug Deliv Rev , vol.62 , Issue.14 , pp. 1369-1377
    • Deelman, L.E.1    Declèves, A.E.2    Rychak, J.J.3    Sharma, K.4
  • 57
    • 70450249454 scopus 로고    scopus 로고
    • Microbubble compositions, properties and biomedical applications
    • COI: 1:CAS:528:DC%2BC3cXmtF2qsA%3D%3D, PID: 20574549
    • Sirsi S, Borden M. Microbubble compositions, properties and biomedical applications. Bubble Sci Eng Technol. 2009;1(1-2):3–17. doi:10.1179/175889709X446507.
    • (2009) Bubble Sci Eng Technol , vol.1 , Issue.1-2 , pp. 3-17
    • Sirsi, S.1    Borden, M.2
  • 58
    • 84871099822 scopus 로고    scopus 로고
    • MicroRNAs, transforming growth factor beta-1, and tissue fibrosis
    • Bowen T, Jenkins RH, Fraser DJ. MicroRNAs, transforming growth factor beta-1, and tissue fibrosis. J Pathol. 2013;229(2):274–85. doi:10.1002/path.4119.
    • (2013) J Pathol , vol.229 , Issue.2 , pp. 274-285
    • Bowen, T.1    Jenkins, R.H.2    Fraser, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.