메뉴 건너뛰기




Volumn 127, Issue 10, 2016, Pages 1242-1248

Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIFFERENTIATION; CELL LINEAGE; COLONY FORMING UNIT GM; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; HUMAN; MEGAKARYOBLAST; MEGAKARYOCYTE; MEGAKARYOPOIESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SINGLE CELL ANALYSIS; STEM CELL; STEM CELL SELF-RENEWAL; ANIMAL; CYTOLOGY; LYMPHOID PROGENITOR CELL; LYMPHOPOIESIS; MEGAKARYOCYTE ERYTHROID PROGENITOR; METABOLISM; MYELOPOIESIS; PHYSIOLOGY; THROMBOCYTOPOIESIS;

EID: 84960877754     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-07-607945     Document Type: Review
Times cited : (111)

References (62)
  • 1
    • 0000448725 scopus 로고
    • Modification of irradiation injury in mice and Guinea pigs by bone marrow injections
    • Lorenz E, Uphoff D, Reid TR, Shelton E. Modification of irradiation injury in mice and guinea pigs by bone marrow injections. J Natl Cancer Inst. 1951;12(1):197-201.
    • (1951) J Natl Cancer Inst , vol.12 , Issue.1 , pp. 197-201
    • Lorenz, E.1    Uphoff, D.2    Reid, T.R.3    Shelton, E.4
  • 3
    • 84855885803 scopus 로고    scopus 로고
    • Cell cycle regulation in hematopoietic stem cells
    • Pietras EM, Warr MR, Passegué E. Cell cycle regulation in hematopoietic stem cells. J Cell Biol. 2011;195(5):709-720.
    • (2011) J Cell Biol , vol.195 , Issue.5 , pp. 709-720
    • Pietras, E.M.1    Warr, M.R.2    Passegué, E.3
  • 4
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science. 1988; 241(4861):58-62.
    • (1988) Science , vol.241 , Issue.4861 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 5
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000; 404(6774):193-197.
    • (2000) Nature , vol.404 , Issue.6774 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 6
    • 0029796643 scopus 로고    scopus 로고
    • Characterization of a bipotent erythromegakaryocytic progenitor in human bone marrow
    • Debili N, Coulombel L, Croisille L, et al. Characterization of a bipotent erythromegakaryocytic progenitor in human bone marrow. Blood. 1996;88(4):1284-1296.
    • (1996) Blood , vol.88 , Issue.4 , pp. 1284-1296
    • Debili, N.1    Coulombel, L.2    Croisille, L.3
  • 7
    • 0037015069 scopus 로고    scopus 로고
    • Prospective isolation of human clonogenic common myeloid progenitors
    • Manz MG, Miyamoto T, Akashi K, Weissman IL. Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci USA. 2002;99(18):11872-11877.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.18 , pp. 11872-11877
    • Manz, M.G.1    Miyamoto, T.2    Akashi, K.3    Weissman, I.L.4
  • 8
    • 0037422537 scopus 로고    scopus 로고
    • Characterization of mouse clonogenic megakaryocyte progenitors
    • Nakorn TN, Miyamoto T, Weissman IL. Characterization of mouse clonogenic megakaryocyte progenitors. Proc Natl Acad Sci USA. 2003;100(1):205-210.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.1 , pp. 205-210
    • Nakorn, T.N.1    Miyamoto, T.2    Weissman, I.L.3
  • 9
    • 34848896359 scopus 로고    scopus 로고
    • Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy
    • Pronk CJ, Rossi DJ, Månsson R, et al. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy. Cell Stem Cell. 2007;1(4):428-442.
    • (2007) Cell Stem Cell , vol.1 , Issue.4 , pp. 428-442
    • Pronk, C.J.1    Rossi, D.J.2    Månsson, R.3
  • 10
    • 67749147173 scopus 로고    scopus 로고
    • Common features of megakaryocytes and hematopoietic stem cells: What's the connection?
    • Huang H, Cantor AB. Common features of megakaryocytes and hematopoietic stem cells: what's the connection? J Cell Biochem. 2009; 107(5):857-864.
    • (2009) J Cell Biochem , vol.107 , Issue.5 , pp. 857-864
    • Huang, H.1    Cantor, A.B.2
  • 11
    • 0032477741 scopus 로고    scopus 로고
    • Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin
    • Kimura S, Roberts AW, Metcalf D, Alexander WS. Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. Proc Natl Acad Sci USA. 1998;95(3):1195-1200.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.3 , pp. 1195-1200
    • Kimura, S.1    Roberts, A.W.2    Metcalf, D.3    Alexander, W.S.4
  • 12
    • 36749001043 scopus 로고    scopus 로고
    • Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells
    • Qian H, Buza-Vidas N, Hyland CD, et al. Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells. Cell Stem Cell. 2007;1(6):671-684.
    • (2007) Cell Stem Cell , vol.1 , Issue.6 , pp. 671-684
    • Qian, H.1    Buza-Vidas, N.2    Hyland, C.D.3
  • 13
    • 36748999351 scopus 로고    scopus 로고
    • Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche
    • Yoshihara H, Arai F, Hosokawa K, et al. Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell. 2007;1(6):685-697.
    • (2007) Cell Stem Cell , vol.1 , Issue.6 , pp. 685-697
    • Yoshihara, H.1    Arai, F.2    Hosokawa, K.3
  • 14
    • 33845445939 scopus 로고    scopus 로고
    • Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches
    • Sugiyama T, Kohara H, Noda M, Nagasawa T. Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity. 2006;25(6): 977-988.
    • (2006) Immunity , vol.25 , Issue.6 , pp. 977-988
    • Sugiyama, T.1    Kohara, H.2    Noda, M.3    Nagasawa, T.4
  • 15
    • 0032147012 scopus 로고    scopus 로고
    • The alphachemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion
    • Wang JF, Liu ZY, Groopman JE. The alphachemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood. 1998;92(3):756-764.
    • (1998) Blood , vol.92 , Issue.3 , pp. 756-764
    • Wang, J.F.1    Liu, Z.Y.2    Groopman, J.E.3
  • 16
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Yilmaz OH, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005;121(7):1109-1121.
    • (2005) Cell , vol.121 , Issue.7 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Yilmaz, O.H.4    Terhorst, C.5    Morrison, S.J.6
  • 17
    • 78651486442 scopus 로고    scopus 로고
    • Densely interconnected transcriptional circuits control cell states in human hematopoiesis
    • Novershtern N, Subramanian A, Lawton LN, et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell. 2011;144(2):296-309.
    • (2011) Cell , vol.144 , Issue.2 , pp. 296-309
    • Novershtern, N.1    Subramanian, A.2    Lawton, L.N.3
  • 18
    • 84940446838 scopus 로고    scopus 로고
    • Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations
    • Wilson NK, Kent DG, Buettner F, et al. Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations. Cell Stem Cell. 2015;16(6):712-724.
    • (2015) Cell Stem Cell , vol.16 , Issue.6 , pp. 712-724
    • Wilson, N.K.1    Kent, D.G.2    Buettner, F.3
  • 19
    • 84872901381 scopus 로고    scopus 로고
    • Hematopoiesis and hematopoietic organs in arthropods
    • Grigorian M, Hartenstein V. Hematopoiesis and hematopoietic organs in arthropods. Dev Genes Evol. 2013;223(1-2):103-115.
    • (2013) Dev Genes Evol , vol.223 , Issue.1-2 , pp. 103-115
    • Grigorian, M.1    Hartenstein, V.2
  • 20
    • 2342641311 scopus 로고    scopus 로고
    • The evolving role of platelets in inflammation. J
    • Weyrich AS, Lindemann S, Zimmerman GA. The evolving role of platelets in inflammation. J Thromb Haemost. 2003;1(9):1897-1905.
    • (2003) Thromb Haemost , vol.1 , Issue.9 , pp. 1897-1905
    • Weyrich, A.S.1    Lindemann, S.2    Zimmerman, G.A.3
  • 21
    • 0036672919 scopus 로고    scopus 로고
    • The hare and the tortoise: An embryonic haematopoietic race
    • Godin I, Cumano A. The hare and the tortoise: an embryonic haematopoietic race. Nat Rev Immunol. 2002;2(8):593-604.
    • (2002) Nat Rev Immunol , vol.2 , Issue.8 , pp. 593-604
    • Godin, I.1    Cumano, A.2
  • 22
    • 39349096526 scopus 로고    scopus 로고
    • Hematopoiesis: An evolving paradigm for stem cell biology
    • Orkin SH, Zon LI. Hematopoiesis: an evolving paradigm for stem cell biology. Cell. 2008;132(4): 631-644.
    • (2008) Cell , vol.132 , Issue.4 , pp. 631-644
    • Orkin, S.H.1    Zon, L.I.2
  • 23
    • 0032322725 scopus 로고    scopus 로고
    • Hemangioblast development and regulation
    • Choi K. Hemangioblast development and regulation. Biochem Cell Biol. 1998;76(6): 947-956.
    • (1998) Biochem Cell Biol , vol.76 , Issue.6 , pp. 947-956
    • Choi, K.1
  • 24
    • 33846907357 scopus 로고    scopus 로고
    • The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis
    • Tober J, Koniski A, McGrath KE, et al. The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. Blood. 2007;109(4):1433-1441.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1433-1441
    • Tober, J.1    Koniski, A.2    McGrath, K.E.3
  • 25
    • 84879175412 scopus 로고    scopus 로고
    • Thrombomodulin and the vascular endothelium: Insights into functional, regulatory, and therapeutic aspects
    • Martin FA, Murphy RP, Cummins PM. Thrombomodulin and the vascular endothelium: insights into functional, regulatory, and therapeutic aspects. Am J Physiol Heart Circ Physiol. 2013;304(12):H1585-H1597.
    • (2013) Am J Physiol Heart Circ Physiol , vol.304 , Issue.12 , pp. H1585-H1597
    • Martin, F.A.1    Murphy, R.P.2    Cummins, P.M.3
  • 26
    • 84863683494 scopus 로고    scopus 로고
    • Pharmacological targeting of the thrombomodulinactivated protein C pathway mitigates radiation toxicity
    • Geiger H, Pawar SA, Kerschen EJ, et al. Pharmacological targeting of the thrombomodulinactivated protein C pathway mitigates radiation toxicity. Nat Med. 2012;18(7):1123-1129.
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1123-1129
    • Geiger, H.1    Pawar, S.A.2    Kerschen, E.J.3
  • 27
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell. 1997;91(5):661-672.
    • (1997) Cell , vol.91 , Issue.5 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 28
    • 84931561404 scopus 로고    scopus 로고
    • Unipotent megakaryopoietic pathway bridging hematopoietic stem cells and mature megakaryocytes
    • Nishikii H, Kanazawa Y, Umemoto T, et al. Unipotent megakaryopoietic pathway bridging hematopoietic stem cells and mature megakaryocytes. Stem Cells. 2015;33(7): 2196-2207.
    • (2015) Stem Cells , vol.33 , Issue.7 , pp. 2196-2207
    • Nishikii, H.1    Kanazawa, Y.2    Umemoto, T.3
  • 29
    • 0034749999 scopus 로고    scopus 로고
    • Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(1)c-kit(1) stem cell compartment is accompanied by loss of selfrenewal capacity
    • Adolfsson J, Borge OJ, Bryder D, et al. Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(1)c-kit(1) stem cell compartment is accompanied by loss of selfrenewal capacity. Immunity. 2001;15(4):659-669.
    • (2001) Immunity , vol.15 , Issue.4 , pp. 659-669
    • Adolfsson, J.1    Borge, O.J.2    Bryder, D.3
  • 30
    • 0033000170 scopus 로고    scopus 로고
    • Further characterization of CD34-low/negative mouse hematopoietic stem cells
    • Nakauchi H, Takano H, Ema H, Osawa M. Further characterization of CD34-low/negative mouse hematopoietic stem cells. Ann N Y Acad Sci. 1999;872:57-66.
    • (1999) Ann N Y Acad Sci , vol.872 , pp. 57-66
    • Nakauchi, H.1    Takano, H.2    Ema, H.3    Osawa, M.4
  • 31
    • 0029796633 scopus 로고    scopus 로고
    • Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell
    • Osawa M, Hanada K, Hamada H, Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science. 1996;273(5272):242-245.
    • (1996) Science , vol.273 , Issue.5272 , pp. 242-245
    • Osawa, M.1    Hanada, K.2    Hamada, H.3    Nakauchi, H.4
  • 32
    • 20244387299 scopus 로고    scopus 로고
    • Identification of Flt31 lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment
    • Adolfsson J, Månsson R, Buza-Vidas N, et al. Identification of Flt31 lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment. Cell. 2005;121(2):295-306.
    • (2005) Cell , vol.121 , Issue.2 , pp. 295-306
    • Adolfsson, J.1    Månsson, R.2    Buza-Vidas, N.3
  • 33
    • 15944363056 scopus 로고    scopus 로고
    • Identification of Lin(-)Sca1(1)kit(1)CD34(1)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients
    • Yang L, Bryder D, Adolfsson J, et al. Identification of Lin(-)Sca1(1)kit(1)CD34(1)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients. Blood. 2005;105(7): 2717-2723.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2717-2723
    • Yang, L.1    Bryder, D.2    Adolfsson, J.3
  • 34
    • 1342321666 scopus 로고    scopus 로고
    • Asymmetric division and lineage commitment at the level of hematopoietic stem cells: Inference from differentiation in daughter cell and granddaughter cell pairs
    • Takano H, Ema H, Sudo K, Nakauchi H. Asymmetric division and lineage commitment at the level of hematopoietic stem cells: inference from differentiation in daughter cell and granddaughter cell pairs. J Exp Med. 2004;199(3): 295-302.
    • (2004) J Exp Med , vol.199 , Issue.3 , pp. 295-302
    • Takano, H.1    Ema, H.2    Sudo, K.3    Nakauchi, H.4
  • 35
    • 33746208874 scopus 로고    scopus 로고
    • New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt31 multipotent hematopoietic progenitors
    • Forsberg EC, Serwold T, Kogan S, Weissman IL, Passegué E. New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt31 multipotent hematopoietic progenitors. Cell. 2006; 126(2):415-426.
    • (2006) Cell , vol.126 , Issue.2 , pp. 415-426
    • Forsberg, E.C.1    Serwold, T.2    Kogan, S.3    Weissman, I.L.4    Passegué, E.5
  • 36
    • 0035871894 scopus 로고    scopus 로고
    • Cyclophosphamide/granulocyte colonystimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle
    • Wright DE, Cheshier SH, Wagers AJ, Randall TD, Christensen JL, Weissman IL. Cyclophosphamide/granulocyte colonystimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle. Blood. 2001; 97(8):2278-2285.
    • (2001) Blood , vol.97 , Issue.8 , pp. 2278-2285
    • Wright, D.E.1    Cheshier, S.H.2    Wagers, A.J.3    Randall, T.D.4    Christensen, J.L.5    Weissman, I.L.6
  • 37
    • 33746906644 scopus 로고    scopus 로고
    • Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors
    • Lai AY, Kondo M. Asymmetrical lymphoid and myeloid lineage commitment in multipotent hematopoietic progenitors. J Exp Med. 2006; 203(8):1867-1873.
    • (2006) J Exp Med , vol.203 , Issue.8 , pp. 1867-1873
    • Lai, A.Y.1    Kondo, M.2
  • 39
    • 43549088844 scopus 로고    scopus 로고
    • Downregulation of Mpl marks the transition to lymphoidprimed multipotent progenitors with gradual loss of granulocyte-monocyte potential
    • Luc S, Anderson K, Kharazi S, et al. Downregulation of Mpl marks the transition to lymphoidprimed multipotent progenitors with gradual loss of granulocyte-monocyte potential. Blood. 2008; 111(7):3424-3434.
    • (2008) Blood , vol.111 , Issue.7 , pp. 3424-3434
    • Luc, S.1    Anderson, K.2    Kharazi, S.3
  • 40
    • 34848883146 scopus 로고    scopus 로고
    • Reciprocal activation of GATA-1 and PU. 1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages
    • Arinobu Y, Mizuno S, Chong Y, et al. Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages. Cell Stem Cell. 2007;1(4):416-427.
    • (2007) Cell Stem Cell , vol.1 , Issue.4 , pp. 416-427
    • Arinobu, Y.1    Mizuno, S.2    Chong, Y.3
  • 41
    • 84860343741 scopus 로고    scopus 로고
    • Stem cell heterogeneity: Implications for aging and regenerative medicine
    • Muller-Sieburg CE, Sieburg HB, Bernitz JM, Cattarossi G. Stem cell heterogeneity: implications for aging and regenerative medicine. Blood. 2012;119(17):3900-3907.
    • (2012) Blood , vol.119 , Issue.17 , pp. 3900-3907
    • Muller-Sieburg, C.E.1    Sieburg, H.B.2    Bernitz, J.M.3    Cattarossi, G.4
  • 42
    • 77449145533 scopus 로고    scopus 로고
    • Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1
    • Challen GA, Boles NC, Chambers SM, Goodell MA. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell. 2010;6(3):265-278.
    • (2010) Cell Stem Cell , vol.6 , Issue.3 , pp. 265-278
    • Challen, G.A.1    Boles, N.C.2    Chambers, S.M.3    Goodell, Ma.4
  • 43
    • 2542473275 scopus 로고    scopus 로고
    • Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness
    • Muller-Sieburg CE, Cho RH, Karlsson L, Huang JF, Sieburg HB. Myeloid-biased hematopoietic stem cells have extensive self-renewal capacity but generate diminished lymphoid progeny with impaired IL-7 responsiveness. Blood. 2004; 103(11):4111-4118.
    • (2004) Blood , vol.103 , Issue.11 , pp. 4111-4118
    • Muller-Sieburg, C.E.1    Cho, R.H.2    Karlsson, L.3    Huang, J.F.4    Sieburg, H.B.5
  • 44
    • 84857873445 scopus 로고    scopus 로고
    • Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs
    • Benz C, Copley MR, Kent DG, et al. Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell. 2012;10(3):273-283.
    • (2012) Cell Stem Cell , vol.10 , Issue.3 , pp. 273-283
    • Benz, C.1    Copley, M.R.2    Kent, D.G.3
  • 45
    • 34547692981 scopus 로고    scopus 로고
    • Long-term propagation of distinct hematopoietic differentiation programs in vivo
    • Dykstra B, Kent D, Bowie M, et al. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell. 2007;1(2):218-229.
    • (2007) Cell Stem Cell , vol.1 , Issue.2 , pp. 218-229
    • Dykstra, B.1    Kent, D.2    Bowie, M.3
  • 46
    • 77950418688 scopus 로고    scopus 로고
    • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    • Beerman I, Bhattacharya D, Zandi S, et al. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci USA. 2010;107(12):5465-5470.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.12 , pp. 5465-5470
    • Beerman, I.1    Bhattacharya, D.2    Zandi, S.3
  • 47
    • 84880790360 scopus 로고    scopus 로고
    • CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age
    • Gekas C, Graf T. CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood. 2013;121(22): 4463-4472.
    • (2013) Blood , vol.121 , Issue.22 , pp. 4463-4472
    • Gekas, C.1    Graf, T.2
  • 48
    • 84885634008 scopus 로고    scopus 로고
    • Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
    • Sanjuan-Pla A, Macaulay IC, Jensen CT, et al. Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy. Nature. 2013;502(7470):232-236.
    • (2013) Nature , vol.502 , Issue.7470 , pp. 232-236
    • Sanjuan-Pla, A.1    Macaulay, I.C.2    Jensen, C.T.3
  • 49
    • 84893803625 scopus 로고    scopus 로고
    • High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias
    • Shin JY, Hu W, Naramura M, Park CY. High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias. J Exp Med. 2014;211(2):217-231.
    • (2014) J Exp Med , vol.211 , Issue.2 , pp. 217-231
    • Shin, J.Y.1    Hu, W.2    Naramura, M.3    Park, C.Y.4
  • 50
    • 84893796026 scopus 로고    scopus 로고
    • Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells
    • Grinenko T, Arndt K, Portz M, et al. Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. J Exp Med. 2014;211(2):209-215.
    • (2014) J Exp Med , vol.211 , Issue.2 , pp. 209-215
    • Grinenko, T.1    Arndt, K.2    Portz, M.3
  • 51
    • 84883428326 scopus 로고    scopus 로고
    • Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells
    • Yamamoto R, Morita Y, Ooehara J, et al. Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells. Cell. 2013;154(5):1112-1126.
    • (2013) Cell , vol.154 , Issue.5 , pp. 1112-1126
    • Yamamoto, R.1    Morita, Y.2    Ooehara, J.3
  • 52
    • 84866267322 scopus 로고    scopus 로고
    • Mapping differentiation pathways from hematopoietic stem cells using Flk2/Flt3 lineage tracing
    • Boyer SW, Beaudin AE, Forsberg EC. Mapping differentiation pathways from hematopoietic stem cells using Flk2/Flt3 lineage tracing. Cell Cycle. 2012;11(17):3180-3188.
    • (2012) Cell Cycle , vol.11 , Issue.17 , pp. 3180-3188
    • Boyer, S.W.1    Beaudin, A.E.2    Forsberg, E.C.3
  • 53
    • 79959919129 scopus 로고    scopus 로고
    • All hematopoietic cells develop from hematopoietic stem cells through Flk2/Flt3-positive progenitor cells
    • Boyer SW, Schroeder AV, Smith-Berdan S, Forsberg EC. All hematopoietic cells develop from hematopoietic stem cells through Flk2/Flt3-positive progenitor cells. Cell Stem Cell. 2011; 9(1):64-73.
    • (2011) Cell Stem Cell , vol.9 , Issue.1 , pp. 64-73
    • Boyer, S.W.1    Schroeder, A.V.2    Smith-Berdan, S.3    Forsberg, E.C.4
  • 54
    • 84952628356 scopus 로고    scopus 로고
    • Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
    • Haas S, Hansson J, Klimmeck D, et al. Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors. Cell Stem Cell. 2015;17(4):422-434.
    • (2015) Cell Stem Cell , vol.17 , Issue.4 , pp. 422-434
    • Haas, S.1    Hansson, J.2    Klimmeck, D.3
  • 55
    • 84928923099 scopus 로고    scopus 로고
    • Making sense of hematopoietic stem cell niches
    • Boulais PE, Frenette PS. Making sense of hematopoietic stem cell niches. Blood. 2015; 125(17):2621-2629.
    • (2015) Blood , vol.125 , Issue.17 , pp. 2621-2629
    • Boulais, P.E.1    Frenette, P.S.2
  • 56
    • 84879490265 scopus 로고    scopus 로고
    • Megakaryocytes colocalise with hemopoietic stem cells and release cytokines that up-regulate stem cell proliferation
    • Heazlewood SY, Neaves RJ, Williams B, Haylock DN, Adams TE, Nilsson SK. Megakaryocytes colocalise with hemopoietic stem cells and release cytokines that up-regulate stem cell proliferation. Stem Cell Res (Amst). 2013;11(2):782-792.
    • (2013) Stem Cell Res (Amst) , vol.11 , Issue.2 , pp. 782-792
    • Heazlewood, S.Y.1    Neaves, R.J.2    Williams, B.3    Haylock, D.N.4    Adams, T.E.5    Nilsson, S.K.6
  • 57
    • 84892610064 scopus 로고    scopus 로고
    • The bone marrow niche for haematopoietic stem cells
    • Morrison SJ, Scadden DT. The bone marrow niche for haematopoietic stem cells. Nature. 2014; 505(7483):327-334.
    • (2014) Nature , vol.505 , Issue.7483 , pp. 327-334
    • Morrison, S.J.1    Scadden, D.T.2
  • 58
    • 84883571576 scopus 로고    scopus 로고
    • Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning
    • Olson TS, Caselli A, Otsuru S, et al. Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning. Blood. 2013; 121(26):5238-5249.
    • (2013) Blood , vol.121 , Issue.26 , pp. 5238-5249
    • Olson, T.S.1    Caselli, A.2    Otsuru, S.3
  • 59
    • 84964312389 scopus 로고    scopus 로고
    • Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion
    • Bruns I, Lucas D, Pinho S, et al. Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nat Med. 2014;20(11): 1315-1320.
    • (2014) Nat Med , vol.20 , Issue.11 , pp. 1315-1320
    • Bruns, I.1    Lucas, D.2    Pinho, S.3
  • 60
    • 84920448202 scopus 로고    scopus 로고
    • Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells
    • Zhao M, Perry JM, Marshall H, et al. Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells. Nat Med. 2014; 20(11):1321-1326.
    • (2014) Nat Med , vol.20 , Issue.11 , pp. 1321-1326
    • Zhao, M.1    Perry, J.M.2    Marshall, H.3
  • 61
    • 80054719497 scopus 로고    scopus 로고
    • Tracking single hematopoietic stem cells in vivo using highthroughput sequencing in conjunction with viral genetic barcoding
    • Lu R, Neff NF, Quake SR, Weissman IL. Tracking single hematopoietic stem cells in vivo using highthroughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol. 2011;29(10): 928-933.
    • (2011) Nat Biotechnol , vol.29 , Issue.10 , pp. 928-933
    • Lu, R.1    Neff, N.F.2    Quake, S.R.3    Weissman, I.L.4
  • 62
    • 78651416188 scopus 로고    scopus 로고
    • Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia
    • Goardon N, Marchi E, Atzberger A, et al. Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia. Cancer Cell. 2011;19(1):138-152.
    • (2011) Cancer Cell , vol.19 , Issue.1 , pp. 138-152
    • Goardon, N.1    Marchi, E.2    Atzberger, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.