Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

Journal of Experimental Medicine

Volumn 205, Issue 7, 2008, Pages 1659-1672

  Xia, Hong ^a   Diebold, Deanna ^a   Nho, Richard ^a   Perlman, David ^a   Kleidon, Jill ^a   Kahm, Judy ^a   Avdulov, Svetlana ^a   Peterson, Mark ^a   Nerva, John ^a   Bitterman, Peter ^a   Henke, Craig ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; INTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE B; TENSIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; FIBROBLAST; FIBROSING ALVEOLITIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG FIBROBLAST; LUNG INJURY; LUNG PARENCHYMA; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS, CD29; CELL LINE; CELL PROLIFERATION; COLLAGEN TYPE I; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; HUMANS; MALE; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; PULMONARY ALVEOLI; PULMONARY FIBROSIS; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION;

EID: 46949087012     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20080001     Document Type: Article

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