The membrane protein of severe acute respiratory syndrome coronavirus functions as a novel cytosolic pathogen-associated molecular pattern to promote beta interferon induction via a toll-like-receptor-related TRAF3-independent mechanism

mBio

Volumn 7, Issue 1, 2016, Pages

  Wang, Yi ^a   Liu, Li ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BETA INTERFERON; BREFELDIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; MEMBRANE PROTEIN; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PATHOGEN ASSOCIATED MOLECULAR PATTERN; PROTEIN KINASE; RETINOIC ACID INDUCIBLE PROTEIN I; TANK1 PROTEIN; TIRAP PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG; M PROTEIN, CORONAVIRUS; MATRIX PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; GENE EXPRESSION; HEK293 CELL LINE; HUMAN; HUMAN CELL; INTERFERON INDUCTION; INTERFERON PRODUCTION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SARS CORONAVIRUS; SIGNAL TRANSDUCTION; ANIMAL; EPITHELIUM CELL; IMMUNOLOGY; MACROPHAGE; METABOLISM; VIROLOGY;

ANIMALS; EPITHELIAL CELLS; HUMANS; INTERFERON-BETA; MACROPHAGES; MICE; PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 3; TOLL-LIKE RECEPTORS; VIRAL MATRIX PROTEINS;

EID: 84960155285     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01872-15     Document Type: Article

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