Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane protein

Journal of Virology

Volumn 82, Issue 11, 2008, Pages 5137-5144

  Pacciarini, Filippo ^a   Ghezzi, Silvia ^a   Canducci, Filippo ^a,d   Sims, Amy ^b   Sampaolo, Michela ^a,d   Ferioli, Elena ^c   Clementi, Massimo ^a,d   Poli, Guido ^a,d   Conaldi, Pier Giulio ^e   Baric, Ralph ^b   Vicenzi, Elisa ^a,f  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF INSUBRIA   (Italy)

^d VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^e MEDITERRANEAN INSTITUTE FOR TRANSPLANTATION AND ADVANCED SPECIALIZED THERAPIES ISMETT   (Italy)

^f P2 P3 Laboratories   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ANGIOTENSIN CONVERTING ENZYME 2; GLUTAMIC ACID; MEMBRANE PROTEIN; VIRUS ENVELOPE PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; GENETIC SUSCEPTIBILITY; GLOMERULUS; GLOMERULUS EPITHELIUM; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MESANGIUM; MUTATION; NONHUMAN; PERSISTENT VIRUS INFECTION; PODOCYTE; POINT MUTATION; PRIORITY JOURNAL; SARS CORONAVIRUS; VERO CELL; VIRUS INFECTION; VIRUS REPLICATION;

ADAPTATION, BIOLOGICAL; ANIMALS; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; EPITHELIAL CELLS; HUMANS; KIDNEY; KINETICS; MUTATION; PEPTIDYL-DIPEPTIDASE A; SARS VIRUS; VIRAL MATRIX PROTEINS; VIRUS REPLICATION;

SARS CORONAVIRUS;

EID: 43949138923     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00096-08     Document Type: Article

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