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Volumn 15, Issue 2, 2016, Pages 279-290

Methylene blue alleviates nuclear and mitochondrial abnormalities in progeria

Author keywords

Aging; Methylene blue; Mitochondria; PGC1 ; Progeria

Indexed keywords

ANTIOXIDANT; BETA GALACTOSIDASE; FLUORESCENT DYE; METHYLENE BLUE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROGERIN; PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 84960081958     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12434     Document Type: Article
Times cited : (86)

References (61)
  • 1
    • 77956211109 scopus 로고    scopus 로고
    • Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase
    • Atamna H, Kumar R (2010) Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase. J. Alzheimers Dis. 20(Suppl. 2), S439-S452.
    • (2010) J. Alzheimers Dis. , vol.20 , pp. S439-S452
    • Atamna, H.1    Kumar, R.2
  • 2
    • 40449086359 scopus 로고    scopus 로고
    • Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways
    • Atamna H, Nguyen A, Schultz C, Boyle K, Newberry J, Kato H, Ames BN (2008) Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB J. 22, 703-712.
    • (2008) FASEB J. , vol.22 , pp. 703-712
    • Atamna, H.1    Nguyen, A.2    Schultz, C.3    Boyle, K.4    Newberry, J.5    Kato, H.6    Ames, B.N.7
  • 3
    • 84872225149 scopus 로고    scopus 로고
    • PGC1alpha and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders
    • Austin S, St-Pierre J (2012) PGC1alpha and mitochondrial metabolism-emerging concepts and relevance in ageing and neurodegenerative disorders. J. Cell Sci. 125, 4963-4971.
    • (2012) J. Cell Sci. , vol.125 , pp. 4963-4971
    • Austin, S.1    St-Pierre, J.2
  • 5
    • 84874591240 scopus 로고    scopus 로고
    • The role of mitochondria in aging
    • Bratic A, Larsson N-G (2013) The role of mitochondria in aging. J. Clin. Invest. 123, 951-957.
    • (2013) J. Clin. Invest. , vol.123 , pp. 951-957
    • Bratic, A.1    Larsson, N.-G.2
  • 6
    • 34247356070 scopus 로고    scopus 로고
    • A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells
    • Cao K, Capell BC, Erdos MR, Djabali K, Collins FS (2007) A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells. Proc. Natl Acad. Sci. USA 104, 4949-4954.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 4949-4954
    • Cao, K.1    Capell, B.C.2    Erdos, M.R.3    Djabali, K.4    Collins, F.S.5
  • 8
    • 79959776029 scopus 로고    scopus 로고
    • Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
    • 89ra58
    • Cao K, Graziotto JJ, Blair CD, Mazzulli JR, Erdos MR, Krainc D, Collins FS (2011b) Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Sci. Transl. Med. 3, 89ra58.
    • (2011) Sci. Transl. Med. , vol.3
    • Cao, K.1    Graziotto, J.J.2    Blair, C.D.3    Mazzulli, J.R.4    Erdos, M.R.5    Krainc, D.6    Collins, F.S.7
  • 10
    • 33845286555 scopus 로고    scopus 로고
    • Human laminopathies: nuclei gone genetically awry
    • Capell BC, Collins FS (2006) Human laminopathies: nuclei gone genetically awry. Nat. Rev. Genet. 7, 940-952.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 940-952
    • Capell, B.C.1    Collins, F.S.2
  • 14
    • 33745274726 scopus 로고    scopus 로고
    • Mitochondria: dynamic organelles in disease, aging, and development
    • Chan DC (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125, 1241-1252.
    • (2006) Cell , vol.125 , pp. 1241-1252
    • Chan, D.C.1
  • 15
    • 38049059966 scopus 로고    scopus 로고
    • DNA damage, cellular senescence and organismal ageing: causal or correlative?
    • Chen JH, Hales CN, Ozanne SE (2007) DNA damage, cellular senescence and organismal ageing: causal or correlative? Nucleic Acids Res. 35, 7417-7428.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7417-7428
    • Chen, J.H.1    Hales, C.N.2    Ozanne, S.E.3
  • 17
    • 8344274464 scopus 로고    scopus 로고
    • Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis
    • Csoka AB, English SB, Simkevich CP, Ginzinger DG, Butte AJ, Schatten GP, Rothman FG, Sedivy JM (2004) Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis. Aging Cell 3, 235-243.
    • (2004) Aging Cell , vol.3 , pp. 235-243
    • Csoka, A.B.1    English, S.B.2    Simkevich, C.P.3    Ginzinger, D.G.4    Butte, A.J.5    Schatten, G.P.6    Rothman, F.G.7    Sedivy, J.M.8
  • 21
    • 66449126030 scopus 로고    scopus 로고
    • Nuclear lamins and chromatin: when structure meets function
    • Dechat T, Adam SA, Goldman RD (2009) Nuclear lamins and chromatin: when structure meets function. Adv. Enzyme Regul. 49, 157-166.
    • (2009) Adv. Enzyme Regul. , vol.49 , pp. 157-166
    • Dechat, T.1    Adam, S.A.2    Goldman, R.D.3
  • 23
    • 84857293902 scopus 로고    scopus 로고
    • The role of PGC-1 coactivators in aging skeletal muscle and heart
    • Dillon LM, Rebelo AP, Moraes CT (2012) The role of PGC-1 coactivators in aging skeletal muscle and heart. IUBMB Life 64, 231-241.
    • (2012) IUBMB Life , vol.64 , pp. 231-241
    • Dillon, L.M.1    Rebelo, A.P.2    Moraes, C.T.3
  • 24
    • 84863446004 scopus 로고    scopus 로고
    • Automated image analysis of nuclear shape: what can we learn from a prematurely aged cell?
    • Driscoll MK, Albanese JL, Xiong ZM, Mailman M, Losert W, Cao K (2012) Automated image analysis of nuclear shape: what can we learn from a prematurely aged cell? Aging 4, 119-132.
    • (2012) Aging , vol.4 , pp. 119-132
    • Driscoll, M.K.1    Albanese, J.L.2    Xiong, Z.M.3    Mailman, M.4    Losert, W.5    Cao, K.6
  • 26
    • 33644660537 scopus 로고    scopus 로고
    • PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
    • Finck BN, Kelly DP (2006) PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. J. Clin. Invest. 116, 615-622.
    • (2006) J. Clin. Invest. , vol.116 , pp. 615-622
    • Finck, B.N.1    Kelly, D.P.2
  • 31
    • 84869123846 scopus 로고    scopus 로고
    • Progeria: translational insights from cell biology
    • Gordon LB, Cao K, Collins FS (2012) Progeria: translational insights from cell biology. J. Cell Biol. 199, 9-13.
    • (2012) J. Cell Biol. , vol.199 , pp. 9-13
    • Gordon, L.B.1    Cao, K.2    Collins, F.S.3
  • 34
    • 0024200684 scopus 로고
    • Potential of methylene blue to block oxygen radical generation in reperfusion injury
    • Kelner MJ, Bagnell R, Hale B, Alexander NM (1988) Potential of methylene blue to block oxygen radical generation in reperfusion injury. Basic Life Sci. 49, 895-898.
    • (1988) Basic Life Sci. , vol.49 , pp. 895-898
    • Kelner, M.J.1    Bagnell, R.2    Hale, B.3    Alexander, N.M.4
  • 35
    • 34247171756 scopus 로고    scopus 로고
    • Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans
    • Kimura K, Tanaka N, Nakamura N, Takano S, Ohkuma S (2007) Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans. J. Biol. Chem. 282, 5910-5918.
    • (2007) J. Biol. Chem. , vol.282 , pp. 5910-5918
    • Kimura, K.1    Tanaka, N.2    Nakamura, N.3    Takano, S.4    Ohkuma, S.5
  • 36
    • 0035782650 scopus 로고    scopus 로고
    • Reactive oxygen species and mitochondrial diseases
    • Kirkinezos IG, Moraes CT (2001) Reactive oxygen species and mitochondrial diseases. Semin. Cell Dev. Biol. 12, 449-457.
    • (2001) Semin. Cell Dev. Biol. , vol.12 , pp. 449-457
    • Kirkinezos, I.G.1    Moraes, C.T.2
  • 37
    • 84876714439 scopus 로고    scopus 로고
    • Nuclear damages and oxidative stress: new perspectives for laminopathies
    • Lattanzi G, Marmiroli S, Facchini A, Maraldi NM (2012) Nuclear damages and oxidative stress: new perspectives for laminopathies. Eur. J. Histochem. 56, 284-288.
    • (2012) Eur. J. Histochem. , vol.56 , pp. 284-288
    • Lattanzi, G.1    Marmiroli, S.2    Facchini, A.3    Maraldi, N.M.4
  • 38
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443, 787-795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 42
    • 84873349707 scopus 로고    scopus 로고
    • Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome
    • McCord RP, Nazario-Toole A, Zhang H, Chines PS, Zhan Y, Erdos MR, Collins FS, Dekker J, Cao K (2013) Correlated alterations in genome organization, histone methylation, and DNA-lamin A/C interactions in Hutchinson-Gilford progeria syndrome. Genome Res. 23, 260-269.
    • (2013) Genome Res. , vol.23 , pp. 260-269
    • McCord, R.P.1    Nazario-Toole, A.2    Zhang, H.3    Chines, P.S.4    Zhan, Y.5    Erdos, M.R.6    Collins, F.S.7    Dekker, J.8    Cao, K.9
  • 43
    • 0028861992 scopus 로고
    • Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons
    • Morris RL, Hollenbeck PJ (1995) Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons. J. Cell Biol. 131, 1315-1326.
    • (1995) J. Cell Biol. , vol.131 , pp. 1315-1326
    • Morris, R.L.1    Hollenbeck, P.J.2
  • 44
    • 84898899166 scopus 로고    scopus 로고
    • Molecular dynamics simulations of binding modes between methylene blue and DNA with alternating GC and AT sequences
    • Nogueira JJ, Gonzalez L (2014) Molecular dynamics simulations of binding modes between methylene blue and DNA with alternating GC and AT sequences. Biochemistry 53, 2391-2412.
    • (2014) Biochemistry , vol.53 , pp. 2391-2412
    • Nogueira, J.J.1    Gonzalez, L.2
  • 45
    • 84858376953 scopus 로고    scopus 로고
    • Mitochondria: in sickness and in health
    • Nunnari J, Suomalainen A (2012) Mitochondria: in sickness and in health. Cell 148, 1145-1159.
    • (2012) Cell , vol.148 , pp. 1145-1159
    • Nunnari, J.1    Suomalainen, A.2
  • 46
    • 78650018920 scopus 로고    scopus 로고
    • Cellular and molecular actions of Methylene Blue in the nervous system
    • Oz M, Lorke DE, Hasan M, Petroianu GA (2011) Cellular and molecular actions of Methylene Blue in the nervous system. Med. Res. Rev. 31, 93-117.
    • (2011) Med. Res. Rev. , vol.31 , pp. 93-117
    • Oz, M.1    Lorke, D.E.2    Hasan, M.3    Petroianu, G.A.4
  • 49
    • 17644373758 scopus 로고    scopus 로고
    • Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
    • Scaffidi P, Misteli T (2005) Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat. Med. 11, 440-445.
    • (2005) Nat. Med. , vol.11 , pp. 440-445
    • Scaffidi, P.1    Misteli, T.2
  • 52
    • 84934440015 scopus 로고    scopus 로고
    • Nuclear envelope: connecting structural genome organization to regulation of gene expression
    • (Schirmer EC, de las Heras JI, eds). New York: Springer
    • Stancheva I, Schirmer E (2014) Nuclear envelope: connecting structural genome organization to regulation of gene expression. In Cancer Biology and the Nuclear Envelope, Vol. 773. (Schirmer EC, de las Heras JI, eds). New York: Springer, pp. 209-244.
    • (2014) Cancer Biology and the Nuclear Envelope , vol.773 , pp. 209-244
    • Stancheva, I.1    Schirmer, E.2
  • 53
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics. 25, 1105-1111.
    • (2009) Bioinformatics. , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 56
    • 84879297808 scopus 로고    scopus 로고
    • Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment
    • Villa-Bellosta R, Rivera-Torres J, Osorio FG, Acin-Perez R, Enriquez JA, Lopez-Otin C, Andres V (2013) Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment. Circulation 127, 2442-2451.
    • (2013) Circulation , vol.127 , pp. 2442-2451
    • Villa-Bellosta, R.1    Rivera-Torres, J.2    Osorio, F.G.3    Acin-Perez, R.4    Enriquez, J.A.5    Lopez-Otin, C.6    Andres, V.7
  • 57
    • 74149087114 scopus 로고    scopus 로고
    • Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients
    • Viteri G, Chung YW, Stadtman ER (2010) Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients. Mech. Ageing Dev. 131, 2-8.
    • (2010) Mech. Ageing Dev. , vol.131 , pp. 2-8
    • Viteri, G.1    Chung, Y.W.2    Stadtman, E.R.3
  • 58
    • 34447108990 scopus 로고    scopus 로고
    • Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampus
    • Wang X, Pal R, Chen XW, Kumar KN, Kim OJ, Michaelis EK (2007) Genome-wide transcriptome profiling of region-specific vulnerability to oxidative stress in the hippocampus. Genomics 90, 201-212.
    • (2007) Genomics , vol.90 , pp. 201-212
    • Wang, X.1    Pal, R.2    Chen, X.W.3    Kumar, K.N.4    Kim, O.J.5    Michaelis, E.K.6
  • 60
    • 84877642990 scopus 로고    scopus 로고
    • An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells
    • Xiong ZM, LaDana C, Wu D, Cao K (2013) An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells. Aging 5, 288-303.
    • (2013) Aging , vol.5 , pp. 288-303
    • Xiong, Z.M.1    LaDana, C.2    Wu, D.3    Cao, K.4
  • 61
    • 84901844237 scopus 로고    scopus 로고
    • Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1
    • Zhang H, Xiong ZM, Cao K (2014) Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1. Proc. Natl Acad. Sci. USA 111, E2261-2270.
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E2261-E2270
    • Zhang, H.1    Xiong, Z.M.2    Cao, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.