메뉴 건너뛰기




Volumn 6, Issue 1, 2016, Pages 54-64

Silencing of CD44 in Glioma Leads to Changes in Cytoskeletal Protein Expression and Cellular Biomechanical Deformation Properties as Measured by AFM Nanoindentation

Author keywords

Atomic force microscopy (AFM); Cell stiffness; Cytoskeleton; Glioma; Migration

Indexed keywords

ADHESION; ATOMIC FORCE MICROSCOPY; BIOMECHANICS; CELL CULTURE; CELLS; CYTOLOGY; DEFORMATION; ENZYME ACTIVITY; ENZYME INHIBITION; HYALURONIC ACID; NANOINDENTATION; PROTEINS; STIFFNESS; TISSUE; TUMORS;

EID: 84959566184     PISSN: 21911630     EISSN: 21911649     Source Type: Journal    
DOI: 10.1007/s12668-015-0189-2     Document Type: Article
Times cited : (14)

References (71)
  • 1
    • 84919650367 scopus 로고    scopus 로고
    • Engineering strategies to mimic the glioblastoma microenvironment
    • Rape, A., Ananthanarayanan, B., Kumar, S. (2014). Engineering strategies to mimic the glioblastoma microenvironment. Advanced Drug Delivery Reviews, 79–80, 172–183.
    • (2014) Advanced Drug Delivery Reviews , vol.79-80 , pp. 172-183
    • Rape, A.1    Ananthanarayanan, B.2    Kumar, S.3
  • 2
    • 84929442388 scopus 로고    scopus 로고
    • Targeting adaptive glioblastoma: an overview of proliferation and invasion
    • Xie, Q., Mittal, S., Berens, M. E. (2014). Targeting adaptive glioblastoma: an overview of proliferation and invasion. Neuro-Oncology, 16, 1575–1584.
    • (2014) Neuro-Oncology , vol.16 , pp. 1575-1584
    • Xie, Q.1    Mittal, S.2    Berens, M.E.3
  • 3
    • 84905467758 scopus 로고    scopus 로고
    • CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility
    • Kim, Y., & Kumar, S. (2014). CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility. Molecular Cancer Research, 12, 1416–1429.
    • (2014) Molecular Cancer Research , vol.12 , pp. 1416-1429
    • Kim, Y.1    Kumar, S.2
  • 4
    • 84855329031 scopus 로고    scopus 로고
    • The effects of cancer progression on the viscoelasticity of ovarian cell cytoskeleton structures
    • Ketene, A. N., Schmelz, E. M., Roberts, P. C., Agah, M. (2012). The effects of cancer progression on the viscoelasticity of ovarian cell cytoskeleton structures. Nanomedicine, 8, 93–102.
    • (2012) Nanomedicine , vol.8 , pp. 93-102
    • Ketene, A.N.1    Schmelz, E.M.2    Roberts, P.C.3    Agah, M.4
  • 5
    • 84903532893 scopus 로고    scopus 로고
    • Biomechanical profile of cancer stem-like/tumor-initiating cells derived from a progressive ovarian cancer model
    • Babahosseini, H., Ketene, A. N., Schmelz, E. M., Roberts, P. C., Agah, M. (2014). Biomechanical profile of cancer stem-like/tumor-initiating cells derived from a progressive ovarian cancer model. Nanomedicine, 10, 1013–1019.
    • (2014) Nanomedicine , vol.10 , pp. 1013-1019
    • Babahosseini, H.1    Ketene, A.N.2    Schmelz, E.M.3    Roberts, P.C.4    Agah, M.5
  • 7
    • 79960942460 scopus 로고    scopus 로고
    • Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines
    • Swaminathan, V., Mythreye, K., O’Brien, E. T., Berchuck, A., Blobe, G. C., Superfine, R. (2011). Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. Cancer Research, 71, 5075–5080.
    • (2011) Cancer Research , vol.71 , pp. 5075-5080
    • Swaminathan, V.1    Mythreye, K.2    O’Brien, E.T.3    Berchuck, A.4    Blobe, G.C.5    Superfine, R.6
  • 8
    • 23844488162 scopus 로고    scopus 로고
    • Regulation of cancer cell motility through actin reorganization
    • Yamazaki, D., Kurisu, S., Takenawa, T. (2005). Regulation of cancer cell motility through actin reorganization. Cancer Science, 96, 379–386.
    • (2005) Cancer Science , vol.96 , pp. 379-386
    • Yamazaki, D.1    Kurisu, S.2    Takenawa, T.3
  • 9
    • 2942756037 scopus 로고    scopus 로고
    • Microfilament actin remodeling as a potential target for cancer drug development
    • Rao, J., & Li, N. (2004). Microfilament actin remodeling as a potential target for cancer drug development. Current Cancer Drug Targets, 4, 345–354.
    • (2004) Current Cancer Drug Targets , vol.4 , pp. 345-354
    • Rao, J.1    Li, N.2
  • 10
    • 84891039329 scopus 로고    scopus 로고
    • Increased plasticity of the stiffness of melanoma cells correlates with their acquisition of metastatic properties
    • Weder, G., Hendriks-Balk, M. C., Smajda, R., Rimoldi, D., Liley, M., Heinzelmann, H., et al. (2014). Increased plasticity of the stiffness of melanoma cells correlates with their acquisition of metastatic properties. Nanomedicine, 10, 141–148.
    • (2014) Nanomedicine , vol.10 , pp. 141-148
    • Weder, G.1    Hendriks-Balk, M.C.2    Smajda, R.3    Rimoldi, D.4    Liley, M.5    Heinzelmann, H.6
  • 13
    • 34249864531 scopus 로고    scopus 로고
    • Biomechanics and biophysics of cancer cells
    • Suresh, S. (2007). Biomechanics and biophysics of cancer cells. Acta Biomaterialia, 3, 413–438.
    • (2007) Acta Biomaterialia , vol.3 , pp. 413-438
    • Suresh, S.1
  • 14
    • 0026354055 scopus 로고
    • Isolation and characterization of human melanoma call variants expressing high and low levels of CD44
    • Birch, M., Mitchell, S., Hart, I. R. (1991). Isolation and characterization of human melanoma call variants expressing high and low levels of CD44. Cancer Research, 51, 6660–6667.
    • (1991) Cancer Research , vol.51 , pp. 6660-6667
    • Birch, M.1    Mitchell, S.2    Hart, I.R.3
  • 15
    • 0025950014 scopus 로고
    • Distinct effects of two CD44 isoforms on tumour growth in vivo
    • Sy, M. S., Guo, Y. J., Stamenkovic, I. (1991). Distinct effects of two CD44 isoforms on tumour growth in vivo. Journal of Experimental Medicine, 174, 859–866.
    • (1991) Journal of Experimental Medicine , vol.174 , pp. 859-866
    • Sy, M.S.1    Guo, Y.J.2    Stamenkovic, I.3
  • 17
    • 0032811484 scopus 로고    scopus 로고
    • CD44s-targeted treatment with monoclonal antibody blocks intercerebral invasion and growth of 9L gliosarcoma
    • Gunia, S., Hussein, S., Radu, D. L., Putz, K. M., Breyer, R., Hecker, H. (1999). CD44s-targeted treatment with monoclonal antibody blocks intercerebral invasion and growth of 9L gliosarcoma. Clinical and Experimental Metastasis, 17, 221–230.
    • (1999) Clinical and Experimental Metastasis , vol.17 , pp. 221-230
    • Gunia, S.1    Hussein, S.2    Radu, D.L.3    Putz, K.M.4    Breyer, R.5    Hecker, H.6
  • 20
    • 84896107633 scopus 로고    scopus 로고
    • Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth
    • Pietras, A., Katz, A. M., Ekström, E. J., Wee, B., Halliday, J. J., Pitter, K. L., et al. (2014). Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth. Cell Stem Cell, 14, 357–369.
    • (2014) Cell Stem Cell , vol.14 , pp. 357-369
    • Pietras, A.1    Katz, A.M.2    Ekström, E.J.3    Wee, B.4    Halliday, J.J.5    Pitter, K.L.6
  • 22
    • 0026019628 scopus 로고
    • The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells
    • Stamenkovic, I., Aruffo, A., Amiot, M. (1991). The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells. EMBO Journal, 10, 343–348.
    • (1991) EMBO Journal , vol.10 , pp. 343-348
    • Stamenkovic, I.1    Aruffo, A.2    Amiot, M.3
  • 24
    • 0030977964 scopus 로고    scopus 로고
    • Molecular and cellular pathology of intrinsic brain tumours
    • Merzak, A., & Pilkington, G. J. (1997). Molecular and cellular pathology of intrinsic brain tumours. Cancer and Metastasis Reviews, 16, 155–177.
    • (1997) Cancer and Metastasis Reviews , vol.16 , pp. 155-177
    • Merzak, A.1    Pilkington, G.J.2
  • 25
    • 0025825209 scopus 로고
    • A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
    • Günthert, U., Hofmann, M., Rudy, W., Reber, S., Zöller, M., Haussmann, I., et al. (1991). A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell, 65, 13–24.
    • (1991) Cell , vol.65 , pp. 13-24
    • Günthert, U.1    Hofmann, M.2    Rudy, W.3    Reber, S.4    Zöller, M.5    Haussmann, I.6
  • 27
    • 84857182500 scopus 로고    scopus 로고
    • Receptors for hyaluronic acid and poliovirus: a combinatorial role in glioma invasion?
    • Maherally, Z., Smith, J. R., An, Q., Pilkington, G. J. (2012). Receptors for hyaluronic acid and poliovirus: a combinatorial role in glioma invasion? PLoS One, 7, e30691.
    • (2012) PLoS One , vol.7 , pp. e30691
    • Maherally, Z.1    Smith, J.R.2    An, Q.3    Pilkington, G.J.4
  • 28
    • 84863048761 scopus 로고    scopus 로고
    • A genetic strategy for the dynamic and graded control of cell mechanics, motility, and matrix remodelling
    • Mackay, J. L., Keung, A. J., Kumar, S. (2012). A genetic strategy for the dynamic and graded control of cell mechanics, motility, and matrix remodelling. Biophysical Journal, 102, 434–442.
    • (2012) Biophysical Journal , vol.102 , pp. 434-442
    • Mackay, J.L.1    Keung, A.J.2    Kumar, S.3
  • 29
    • 84870666677 scopus 로고    scopus 로고
    • A general approach for the microrheology of cancer cells by atomic force microscopy
    • Wang, B., Lancon, P., Bienvenu, C., Vierling, P., Di Giorgio, C., Bossis, G. (2013). A general approach for the microrheology of cancer cells by atomic force microscopy. Micron, 44, 287–297.
    • (2013) Micron , vol.44 , pp. 287-297
    • Wang, B.1    Lancon, P.2    Bienvenu, C.3    Vierling, P.4    Di Giorgio, C.5    Bossis, G.6
  • 30
    • 71749093389 scopus 로고    scopus 로고
    • Dynamic viscoelastic behavior of individual Gram-negative bacterial cells
    • Vadillo-Rodriguez, V., & Dutcher, J. R. (2009). Dynamic viscoelastic behavior of individual Gram-negative bacterial cells. Soft Matter, 5, 5012–5019.
    • (2009) Soft Matter , vol.5 , pp. 5012-5019
    • Vadillo-Rodriguez, V.1    Dutcher, J.R.2
  • 34
    • 0035501157 scopus 로고    scopus 로고
    • Mechanical properties of in situ demineralised human enamel measured by AFM nanoindentation
    • Finke, M., Hughes, J. A., Parker, D. M., Jandt, K. D. (2001). Mechanical properties of in situ demineralised human enamel measured by AFM nanoindentation. Surface Science, 491, 456–467.
    • (2001) Surface Science , vol.491 , pp. 456-467
    • Finke, M.1    Hughes, J.A.2    Parker, D.M.3    Jandt, K.D.4
  • 36
    • 4644231010 scopus 로고    scopus 로고
    • Using the atomic force microscope to observe and study the ultrastructure of the living BIU-87 cells of the human bladder cancer
    • Chen, B., Wang, Q., Han, L. (2004). Using the atomic force microscope to observe and study the ultrastructure of the living BIU-87 cells of the human bladder cancer. Scanning, 26, 162–166.
    • (2004) Scanning , vol.26 , pp. 162-166
    • Chen, B.1    Wang, Q.2    Han, L.3
  • 41
    • 52649140984 scopus 로고    scopus 로고
    • Mechanical properties of plasma membrane and nuclear envelope measured by scanning probe microscope
    • Yokokawa, M. K., Takeyasu, Yoshimura, S. H. (2008). Mechanical properties of plasma membrane and nuclear envelope measured by scanning probe microscope. Journal of Microscopy, 232, 82–90.
    • (2008) Journal of Microscopy , vol.232 , pp. 82-90
    • Yokokawa, M.K.1    Takeyasu2    Yoshimura, S.H.3
  • 42
    • 79951924332 scopus 로고    scopus 로고
    • AFM stiffness nanotomography of normal, metaplastic and dysplastic human esophageal cells
    • Fuhrmann, A., Staunton, J. R., Nandakumar, V., Banyai, N., Davies, P. C. W., Ros, R. (2011). AFM stiffness nanotomography of normal, metaplastic and dysplastic human esophageal cells. Physical Biology, 8, 015007.
    • (2011) Physical Biology , vol.8 , pp. 015007
    • Fuhrmann, A.1    Staunton, J.R.2    Nandakumar, V.3    Banyai, N.4    Davies, P.C.W.5    Ros, R.6
  • 44
    • 69249105411 scopus 로고    scopus 로고
    • Measuring microenvironment mechanical stress of rat liver during diethylnitrosamine induced hepatocarcinogenesis by atomic force microscope
    • Gang, Z., Qi, Q., Jing, C., Wang, C. Y. (2009). Measuring microenvironment mechanical stress of rat liver during diethylnitrosamine induced hepatocarcinogenesis by atomic force microscope. Microscopy Research and Technique, 72, 672–678.
    • (2009) Microscopy Research and Technique , vol.72 , pp. 672-678
    • Gang, Z.1    Qi, Q.2    Jing, C.3    Wang, C.Y.4
  • 45
    • 84867117776 scopus 로고    scopus 로고
    • Cell stiffness is a biomarker of the metastatic potential of ovarian cancer cells
    • Xu, W., Mezencev, R., Kim, B., Wang, L., McDonald, J., Sulchek, T. (2012). Cell stiffness is a biomarker of the metastatic potential of ovarian cancer cells. PLoS One, 7(10), e46609.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e46609
    • Xu, W.1    Mezencev, R.2    Kim, B.3    Wang, L.4    McDonald, J.5    Sulchek, T.6
  • 46
    • 77950365628 scopus 로고    scopus 로고
    • Intracellular particle tracking as a tool for tumor cell characterization
    • Li, Y. X., Schnekenburger, J., Duits, M. H. G. (2009). Intracellular particle tracking as a tool for tumor cell characterization. Journal Biomedical Optics, 14, 064005.
    • (2009) Journal Biomedical Optics , vol.14 , pp. 064005
    • Li, Y.X.1    Schnekenburger, J.2    Duits, M.H.G.3
  • 47
    • 77958580293 scopus 로고    scopus 로고
    • Stress relaxation and creep on living cells with the atomic force microscope: a means to calculate elastic moduli and viscosities of cell components
    • Moreno-Flores, S., Benitez, R., Vivanco, M. D., Toca-Herrera, J. L. (2010). Stress relaxation and creep on living cells with the atomic force microscope: a means to calculate elastic moduli and viscosities of cell components. Nanotechnology, 21, 445101.
    • (2010) Nanotechnology , vol.21 , pp. 445101
    • Moreno-Flores, S.1    Benitez, R.2    Vivanco, M.D.3    Toca-Herrera, J.L.4
  • 48
    • 54249143499 scopus 로고    scopus 로고
    • Measurement of elastic properties of prostate cancer cells using AFM
    • Faria, E. C., Ma, N., Gazi, E., Gardner, P., Brown, M., Noel, N. W., et al. (2008). Measurement of elastic properties of prostate cancer cells using AFM. Analyst, 133, 1498–1500.
    • (2008) Analyst , vol.133 , pp. 1498-1500
    • Faria, E.C.1    Ma, N.2    Gazi, E.3    Gardner, P.4    Brown, M.5    Noel, N.W.6
  • 49
    • 78149471066 scopus 로고    scopus 로고
    • Effect of collagen I and fibronectin on the adhesion, elasticity and cytoskeletal organization of prostate cancer cells
    • Docheva, D., Padula, D., Schieker, M., Clausen-Schaumann, H. (2010). Effect of collagen I and fibronectin on the adhesion, elasticity and cytoskeletal organization of prostate cancer cells. Biochemical and Biophysical Research Communications, 402, 361–366.
    • (2010) Biochemical and Biophysical Research Communications , vol.402 , pp. 361-366
    • Docheva, D.1    Padula, D.2    Schieker, M.3    Clausen-Schaumann, H.4
  • 50
    • 84865808422 scopus 로고    scopus 로고
    • Comparison of mechanical properties of normal and malignant thyroid cells
    • Prabhune, M., Belge, G., Dotzauer, A., Bullerdiek, J., Radmacher, M. (2012). Comparison of mechanical properties of normal and malignant thyroid cells. Micron, 43, 1267–1272.
    • (2012) Micron , vol.43 , pp. 1267-1272
    • Prabhune, M.1    Belge, G.2    Dotzauer, A.3    Bullerdiek, J.4    Radmacher, M.5
  • 51
    • 84893079204 scopus 로고    scopus 로고
    • Brain tumour cell line authentication, an efficient alternative to capillary electrophoresis by using a microfluidics-based system
    • An, Q., Fillmore, H. L., Vouri, M., Pilkington, G. J. (2014). Brain tumour cell line authentication, an efficient alternative to capillary electrophoresis by using a microfluidics-based system. Neuro-Oncology, 16, 265–273.
    • (2014) Neuro-Oncology , vol.16 , pp. 265-273
    • An, Q.1    Fillmore, H.L.2    Vouri, M.3    Pilkington, G.J.4
  • 52
    • 27944457267 scopus 로고    scopus 로고
    • Quantification issues in the identification of nanoscale regions of homopolymers using modulus measurement via AFM nanoindentation
    • Clifford, C. A., & Seah, M. P. (2005). Quantification issues in the identification of nanoscale regions of homopolymers using modulus measurement via AFM nanoindentation. Applied Surface Science, 252, 1915–1933.
    • (2005) Applied Surface Science , vol.252 , pp. 1915-1933
    • Clifford, C.A.1    Seah, M.P.2
  • 54
    • 77957765211 scopus 로고    scopus 로고
    • Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study
    • McPhee, G., Dalby, M. J., Riehle, M., Yin, H. B. (2010). Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study. Medical and Biological Engineering and Computing, 48, 1043–1053.
    • (2010) Medical and Biological Engineering and Computing , vol.48 , pp. 1043-1053
    • McPhee, G.1    Dalby, M.J.2    Riehle, M.3    Yin, H.B.4
  • 56
    • 0037783430 scopus 로고    scopus 로고
    • Nanoscale mapping of the elasticity of microbial cells by atomic force microscopy
    • Touham, A., Nysten, B., Dufrene, Y. F. (2003). Nanoscale mapping of the elasticity of microbial cells by atomic force microscopy. Langmuir, 19, 4539–4543.
    • (2003) Langmuir , vol.19 , pp. 4539-4543
    • Touham, A.1    Nysten, B.2    Dufrene, Y.F.3
  • 57
    • 0036231598 scopus 로고    scopus 로고
    • Determination of elastic moduli of thin layers of soft material using the atomic force microscope
    • Dimitriadis, E. K., Horkay, F., Maresca, J., Kachar, B., Chadwick, R. S. (2002). Determination of elastic moduli of thin layers of soft material using the atomic force microscope. Biophysical Journal, 82, 2798–2810.
    • (2002) Biophysical Journal , vol.82 , pp. 2798-2810
    • Dimitriadis, E.K.1    Horkay, F.2    Maresca, J.3    Kachar, B.4    Chadwick, R.S.5
  • 59
    • 0021229094 scopus 로고
    • Production of glial fibrillary acidic protein (GFAP) by neoplastic cells: adaptation to the microenvironment
    • Herpers, M. J., Budka, H., McCormick, D. (1984). Production of glial fibrillary acidic protein (GFAP) by neoplastic cells: adaptation to the microenvironment. Acta Neuropathologica, 64, 333–338.
    • (1984) Acta Neuropathologica , vol.64 , pp. 333-338
    • Herpers, M.J.1    Budka, H.2    McCormick, D.3
  • 61
    • 3543113113 scopus 로고    scopus 로고
    • Intermediate filaments mediate cytoskeletal crosstalk
    • Chang, L., & Goldman, R. D. (2004). Intermediate filaments mediate cytoskeletal crosstalk. Molecular and Cellular Biology, 5, 601–613.
    • (2004) Molecular and Cellular Biology , vol.5 , pp. 601-613
    • Chang, L.1    Goldman, R.D.2
  • 62
    • 84894273898 scopus 로고    scopus 로고
    • The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease
    • Tai, P. W., Zaidi, S. K., Wu, H., Grandy, R. A., Montecino, M., van Wijnen, A. J., et al. (2014). The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease. Journal of Cellular Physiology, 229, 711–727.
    • (2014) Journal of Cellular Physiology , vol.229 , pp. 711-727
    • Tai, P.W.1    Zaidi, S.K.2    Wu, H.3    Grandy, R.A.4    Montecino, M.5    van Wijnen, A.J.6
  • 63
    • 84897505936 scopus 로고    scopus 로고
    • Nuclear assembly as a target for anti-cancer therapies
    • Gorjanacz, M. (2014). Nuclear assembly as a target for anti-cancer therapies. Nucleus, 5, 47–55.
    • (2014) Nucleus , vol.5 , pp. 47-55
    • Gorjanacz, M.1
  • 64
    • 84935835905 scopus 로고    scopus 로고
    • The tethering of chromatin to the nuclear envelope supports nuclear mechanics
    • Schreiner, S. M., Koo, P. K., Zhao, Y., Mochrie, S. G. J., King, M. C. (2015). The tethering of chromatin to the nuclear envelope supports nuclear mechanics. Nature Communications, 6, 7159–7171.
    • (2015) Nature Communications , vol.6 , pp. 7159-7171
    • Schreiner, S.M.1    Koo, P.K.2    Zhao, Y.3    Mochrie, S.G.J.4    King, M.C.5
  • 67
    • 84904286910 scopus 로고    scopus 로고
    • The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue
    • Swift, J., & Discher, D. E. (2014). The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue. Journal of Cell Science, 127, 3005–3015.
    • (2014) Journal of Cell Science , vol.127 , pp. 3005-3015
    • Swift, J.1    Discher, D.E.2
  • 69
    • 68049139442 scopus 로고    scopus 로고
    • Influence of lamin A on the mechanical properties of amphibian oocyte nuclei measured by atomic force microscopy
    • Schape, J., Prauße, S., Radmacher, M., Stick, R. (2009). Influence of lamin A on the mechanical properties of amphibian oocyte nuclei measured by atomic force microscopy. Biophysical Journal, 96, 4319–4325.
    • (2009) Biophysical Journal , vol.96 , pp. 4319-4325
    • Schape, J.1    Prauße, S.2    Radmacher, M.3    Stick, R.4
  • 70
    • 84907190414 scopus 로고    scopus 로고
    • Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts
    • Ferrera, D., Canale, C., Marotta, R., Mazzaro, N., Gritti, M., Mazzanti, M., et al. (2014). Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts. FASEB Journal, 28, 3906–3918.
    • (2014) FASEB Journal , vol.28 , pp. 3906-3918
    • Ferrera, D.1    Canale, C.2    Marotta, R.3    Mazzaro, N.4    Gritti, M.5    Mazzanti, M.6
  • 71
    • 84899104611 scopus 로고    scopus 로고
    • The softening of human bladder cancer cells happens at an early stage of the malignancy process
    • Ramos, J. R., Rabijan, J., Garcia, R., Lekka, M. (2014). The softening of human bladder cancer cells happens at an early stage of the malignancy process. Beilstein Journal of Nanotechnology, 5, 447–457.
    • (2014) Beilstein Journal of Nanotechnology , vol.5 , pp. 447-457
    • Ramos, J.R.1    Rabijan, J.2    Garcia, R.3    Lekka, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.