Hyaluronidase can modulate expression of CD44

Experimental Cell Research

Volumn 266, Issue 1, 2001, Pages 167-176

  Stern, Robert ^a   Shuster, Svetlana ^a   Wiley, T S ^b   Formby, Bent ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Rasmus Institute for Medical Research   (United States)

Author keywords

Cancer; CD44; Extracellular matrix; Hyaluronan; Hyaluronidase; Variant exons

Indexed keywords

HERMES ANTIGEN; HYALURONIC ACID; HYALURONIDASE;

ANTIGEN EXPRESSION; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; EXON; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MOUTH CANCER; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA;

EID: 0035872236     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2001.5206     Document Type: Article

References (76)

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7. New CD44 splice variants associated with human breast cancers
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12. New reports blur image of promising metastasis marker
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14. Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin
15. Hyaluronan
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24. CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid (HA)-dependent ovarian tumor cell migration
25. Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation
26. CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration
27. Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the rho family of small G proteins
28. Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins
29. Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth
30. Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton
31. Perturbation of hyaluronan interactions by soluble CD44 inhibits growth of murine mammary carcinoma cells in ascites
32. Induction of apoptosis of metastatic mammary carcinoma cells in vivo by disruption of tumor cell surface CD44 function
33. Induction of fibroblast apoptosis by anti-CD44 antibody: Implications for the treatment of fibroproliferative lung disease
34. Engagement of variant CD44 confers resistance to anti-integrin antibody-mediated apoptosis in a colon carcinoma cell line
35. Distinct patterns of apoptosis in association with modulation of CD44 induced by thrombopoietin and granulocyte-colony stimulating factor during ex vivo expansion of human cord blood CD34+ cells
36. Hyaluronic acid inhibits apoptosis in granulosa cells via CD44
37. Functional role of cyclin A on induction of fibroblast apoptosis due to ligation of CD44 matrix receptor by anti-CD44 antibody
38. Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells
39. Purification, cloning, and expression of human plasma hyaluronidase
40. The hyaluronidase gene HYAL1 maps to chromosome 3p21.2 - p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus
41. Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31
42. LUCA-1, a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA
43. A substrate-gel assay for hyaluronidase activity
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45. Structural relationship of sperm soluble hyaluronidase to the sperm membrane protein PH-20
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48. A microtiter-based assay for hyaluronidase activity not requiring specialized reagents
49. The turbidimetric assay of hyaluronidase
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51. Affinity chromatography on immobilized hyaluronate and its application to the isolation of hyaluronate binding properties from cartilage
52. Age-dependent changes of hyaluronan in human skin
53. Patterns of hyaluronan staining are modified by fixation techniques
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65. The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan
66. CD44 positive macrophages take up hyaluronan during lung development
67. Internalization of hyaluronan by chondrocytes occurs via receptor-mediated endocytosis
68. Phosphorylation stabilizes alternatively spliced CD44 mRNA transcripts in breast cancer cells: Inhibition by antisense complementary to casein kinase II mRNA
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70. Hyaluronan receptor-directed assembly of chondrocyte pericellular matrix
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72. Epican, a heparan/chondroitin sulfate proteoglycan form of CD44, mediates cell-cell adhesion
73. CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor
74. Novel variants of CD44 arising from alternative splicing: Changes in the CD44 alternative splicing pattern of MCF-7 breast carcinoma cells treated with hyaluronidase
75. Bcl-2, survivin and variant CD44 v7-v10 are downregulated and p53 is upregulated in breast cancer cells by progesterone: Inhibition of cell growth and induction of apoptosis