A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells

PLoS Pathogens

Volumn 12, Issue 2, 2016, Pages

  Davis, Zachary B ^a,g   Cogswell, Andrew ^a   Scott, Hamish ^b,c   Mertsching, Amanda ^a   Boucau, Julie ^d   Wambua, Daniel ^d   Le Gall, Sylvie ^d   Planelles, Vicente ^e   Campbell, Kerry S ^f   Barker, Edward ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^f FOX CHASE CANCER CENTER   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD3 ANTIBODY; CD56 ANTIGEN; CD94 ANTIGEN; GRANULYSIN; GRANZYME; HLA C ANTIGEN; HLA E ANTIGEN; HYBRID PROTEIN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2A; PERFORIN; HLA ANTIGEN CLASS 1; HLA-E ANTIGEN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY D; PEPTIDE;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CHROMIUM RELEASE ASSAY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DEGRANULATION ASSAY; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN T CELL LEUKEMIA VIRUS INFECTION; KIR GENE; KIR2DL GENE; MASTOCYTOMA CELL LINE; MOUSE; NATURAL KILLER CELLS; NONHUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; NATURAL KILLER CELL; T LYMPHOCYTE; VIROLOGY;

HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV INFECTIONS; HIV-1; HLA-C ANTIGENS; HUMANS; KILLER CELLS, NATURAL; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY D; PEPTIDES; RECEPTORS, NATURAL KILLER CELL; T-LYMPHOCYTES;

EID: 84959564450     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005421     Document Type: Article

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