Tumor cell vascular mimicry: Novel targeting opportunity in melanoma

Pharmacology and Therapeutics

Volumn 159, Issue , 2016, Pages 83-92

  Hendrix, Mary J C ^a,b   Seftor, Elisabeth A ^a   Seftor, Richard E B ^a,b   Chao, Jun Tzu ^c   Chien, Du Shieng ^c   Chu, Yi Wen ^c  

^a CHILDREN'S MEMORIAL HOSPITAL   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c TaiRx Inc   (Taiwan)

Author keywords

CVM 1118; Melanoma; Transendothelial phenotype; Tumor cell plasticity; Vascular mimicry; Vascular mimicry pathways

Indexed keywords

BETA CATENIN; EPHRIN A1; EPHRIN RECEPTOR A2; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE 14; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR TWIST; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1;

ANGIOGENESIS; ANTIANGIOGENIC THERAPY; APOPTOSIS; CANCER GROWTH; CANCER PROGNOSIS; CANCER THERAPY; CELL CYCLE ARREST; CELL CYCLE CHECKPOINT; CELL INVASION; CELL PLASTICITY; CELL PROLIFERATION; CELL SELF-RENEWAL; CELL VIABILITY; DOWN REGULATION; EXTRACELLULAR MATRIX; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; INTRACELLULAR SIGNALING; MELANOMA; META ANALYSIS (TOPIC); NEOVASCULARIZATION (PATHOLOGY); PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REVIEW; TUMOR CELL; TUMOR GROWTH; UPREGULATION; VASCULAR MIMICRY; WNT SIGNALING PATHWAY; ANIMAL; HUMAN; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL PLASTICITY; HUMANS; MELANOMA; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION;

EID: 84959486450     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2016.01.006     Document Type: Review

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