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Volumn 7, Issue 10, 2015, Pages 1675-1698

Evading anti-angiogenic therapy: Resistance to anti-angiogenic therapy in solid tumors

Author keywords

Biomarkers; Myeloid cells; Vascular mimicry; VEGF

Indexed keywords

AFLIBERCEPT; AXITINIB; BEVACIZUMAB; BRIVANIB; CEDIRANIB; FLUOROURACIL; FOLINIC ACID; INTERLEUKIN 17; IRINOTECAN; NINTEDANIB; PAZOPANIB; PONATINIB; PROTEIN TYROSINE KINASE; RAMUCIRUMAB; REGORAFENIB; SORAFENIB; SUNITINIB; VANDETANIB; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; VATALANIB;

EID: 84947803699     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (64)

References (144)
  • 2
    • 0000912662 scopus 로고
    • Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transplant ear chamber
    • Ide AG, Baker NH and Sl W. Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transplant ear chamber. Am J Radiol 1939; 42: 891-899.
    • (1939) Am J Radiol , vol.42 , pp. 891-899
    • Ide, A.G.1    Baker, N.H.2    Sl, W.3
  • 3
    • 84959830787 scopus 로고
    • Vascular reactions of normal and malignant tissues in vivo. I. Vascular reactions of mice to wounds and to normal and neoplastic transplants
    • Algire GH and Hw C. Vascular reactions of normal and malignant tissues in vivo. I. Vascular reactions of mice to wounds and to normal and neoplastic transplants. J Natl Cancer Inst 1945; 6: 73-85.
    • (1945) J Natl Cancer Inst , vol.6 , pp. 73-85
    • Algire, G.H.1    Hw, C.2
  • 4
    • 0014365361 scopus 로고
    • Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy
    • Ehrmann RL and Knoth M. Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy. J Natl Cancer Inst 1968; 41: 1329-1341.
    • (1968) J Natl Cancer Inst , vol.41 , pp. 1329-1341
    • Ehrmann, R.L.1    Knoth, M.2
  • 5
    • 0014304893 scopus 로고
    • Tumor angiogenesis: Transfilter diffusion studies in the hamster by the transparent chamber technique
    • Greenblatt M and Shubi P. Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique. J Natl Cancer Inst 1968; 41: 111-124.
    • (1968) J Natl Cancer Inst , vol.41 , pp. 111-124
    • Greenblatt, M.1    Shubi, P.2
  • 6
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285: 1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 8
    • 0034098351 scopus 로고    scopus 로고
    • Angiogenesis: New targets for the development of anticancer chemotherapies
    • Gourley M and Williamson JS. Angiogenesis: new targets for the development of anticancer chemotherapies. Curr Pharm Des 2000; 6: 417-439.
    • (2000) Curr Pharm Des , vol.6 , pp. 417-439
    • Gourley, M.1    Williamson, J.S.2
  • 9
    • 84859575611 scopus 로고    scopus 로고
    • Anti-angiogenesis therapy in cancer: Current challenges and future perspectives
    • Shojaei F. Anti-angiogenesis therapy in cancer: current challenges and future perspectives. Cancer Lett 2012; 320: 130-137.
    • (2012) Cancer Lett , vol.320 , pp. 130-137
    • Shojaei, F.1
  • 10
    • 84891112609 scopus 로고    scopus 로고
    • Vascular permeability and drug delivery in cancers
    • Azzi S, Hebda JK and Gavard J. Vascular permeability and drug delivery in cancers. Front Oncol 2013; 3: 211.
    • (2013) Front Oncol , vol.3 , pp. 211
    • Azzi, S.1    Hebda, J.K.2    Gavard, J.3
  • 11
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005; 307: 58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 13
    • 0035692285 scopus 로고    scopus 로고
    • Possible mechanisms of acquired resistance to antiangiogenic drugs: Implications for the use of combination therapy approaches
    • Kerbel RS, Yu J, Tran J, Man S, Viloria-Petit A, Klement G, Coomber BL and Rak J. Possible mechanisms of acquired resistance to antiangiogenic drugs: implications for the use of combination therapy approaches. Cancer Metastasis Rev 2001; 20: 79-86.
    • (2001) Cancer Metastasis Rev , vol.20 , pp. 79-86
    • Kerbel, R.S.1    Yu, J.2    Tran, J.3    Man, S.4    Viloria-Petit, A.5    Klement, G.6    Coomber, B.L.7    Rak, J.8
  • 14
    • 0033730417 scopus 로고    scopus 로고
    • Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes
    • Braga VM, Betson M, Li X and Lamarche-Vane N. Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes. Mol Biol Cell 2000; 11: 3703-3721.
    • (2000) Mol Biol Cell , vol.11 , pp. 3703-3721
    • Braga, V.M.1    Betson, M.2    Li, X.3    Lamarche-Vane, N.4
  • 16
    • 0034602690 scopus 로고    scopus 로고
    • Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway
    • Mira JP, Benard V, Groffen J, Sanders LC and Knaus UG. Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway. Proc Natl Acad Sci U S A 2000; 97: 185-189.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 185-189
    • Mira, J.P.1    Benard, V.2    Groffen, J.3    Sanders, L.C.4    Knaus, U.G.5
  • 18
    • 57749185027 scopus 로고    scopus 로고
    • Expression of RAC2 in endothelial cells is required for the postnatal neovascular response
    • De P, Peng Q, Traktuev DO, Li W, Yoder MC, March KL and Durden DL. Expression of RAC2 in endothelial cells is required for the postnatal neovascular response. Exp Cell Res 2009; 315: 248-263.
    • (2009) Exp Cell Res , vol.315 , pp. 248-263
    • De, P.1    Peng, Q.2    Traktuev, D.O.3    Li, W.4    Yoder, M.C.5    March, K.L.6    Durden, D.L.7
  • 19
    • 84872534173 scopus 로고    scopus 로고
    • Endothelial cell metabolism and tumour angiogenesis: Glucose and glutamine as essential fuels and lactate as the driving force
    • Polet F and Feron O. Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force. J Intern Med 2013; 273: 156-165.
    • (2013) J Intern Med , vol.273 , pp. 156-165
    • Polet, F.1    Feron, O.2
  • 23
    • 84887121023 scopus 로고    scopus 로고
    • Oncogenes and angiogenesis: A way to personalize anti-angiogenic therapy?
    • Bottos A and Bardelli A. Oncogenes and angiogenesis: a way to personalize anti-angiogenic therapy? Cell Mol Life Sci 2013; 70: 4131-4140.
    • (2013) Cell Mol Life Sci , vol.70 , pp. 4131-4140
    • Bottos, A.1    Bardelli, A.2
  • 24
    • 77950948813 scopus 로고    scopus 로고
    • Evading tumor evasion: Current concepts and perspectives of anti-angiogenic cancer therapy
    • Abdollahi A and Folkman J. Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy. Drug Resist Updat 2010; 13: 16-28.
    • (2010) Drug Resist Updat , vol.13 , pp. 16-28
    • Abdollahi, A.1    Folkman, J.2
  • 26
    • 84879842315 scopus 로고    scopus 로고
    • MicroRNAs and tumor vasculature normalization: Impact on anti-tumor immune response
    • Matejuk A, Collet G, Nadim M, Grillon C and Kieda C. MicroRNAs and tumor vasculature normalization: impact on anti-tumor immune response. Arch Immunol Ther Exp (Warsz) 2013; 61: 285-299.
    • (2013) Arch Immunol Ther Exp (Warsz) , vol.61 , pp. 285-299
    • Matejuk, A.1    Collet, G.2    Nadim, M.3    Grillon, C.4    Kieda, C.5
  • 27
    • 84866181541 scopus 로고    scopus 로고
    • Hypoxia control to normalize pathologic angiogenesis: Potential role for endothelial precursor cells and miRNAs regulation
    • Collet G, Skrzypek K, Grillon C, Matejuk A, El Hafni-Rahbi B, Lamerant-Fayel N and Kieda C. Hypoxia control to normalize pathologic angiogenesis: potential role for endothelial precursor cells and miRNAs regulation. Vascul Pharmacol 2012; 56: 252-261.
    • (2012) Vascul Pharmacol , vol.56 , pp. 252-261
    • Collet, G.1    Skrzypek, K.2    Grillon, C.3    Matejuk, A.4    El Hafni-Rahbi, B.5    Lamerant-Fayel, N.6    Kieda, C.7
  • 28
    • 84903901969 scopus 로고    scopus 로고
    • Anti-angiogenic therapy for cancer: Current progress, unresolved questions and future directions
    • Vasudev NS and Reynolds AR. Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions. Angiogenesis 2014; 17: 471-494.
    • (2014) Angiogenesis , vol.17 , pp. 471-494
    • Vasudev, N.S.1    Reynolds, A.R.2
  • 32
    • 84872068442 scopus 로고    scopus 로고
    • Results from AMBER, a randomized phase 2 study of bevacizumab and bortezomib versus bortezomib in relapsed or refractory multiple myeloma
    • White D, Kassim A, Bhaskar B, Yi J, Wamstad K and Paton VE. Results from AMBER, a randomized phase 2 study of bevacizumab and bortezomib versus bortezomib in relapsed or refractory multiple myeloma. Cancer 2013; 119: 339-347.
    • (2013) Cancer , vol.119 , pp. 339-347
    • White, D.1    Kassim, A.2    Bhaskar, B.3    Yi, J.4    Wamstad, K.5    Paton, V.E.6
  • 36
    • 84878880707 scopus 로고    scopus 로고
    • The Breast Avastin Trial: Phase II study of bevacizumab maintenance therapy after induction chemotherapy with docetaxel and capecitabine for the first-line treatment of patients with locally recurrent or metastatic breast cancer
    • Bisagni G, Musolino A, Panebianco M, De Matteis A, Nuzzo F, Ardizzoni A, Gori S, Gamucci T, Passalacqua R, Gnoni R, Moretti G and Boni C. The Breast Avastin Trial: phase II study of bevacizumab maintenance therapy after induction chemotherapy with docetaxel and capecitabine for the first-line treatment of patients with locally recurrent or metastatic breast cancer. Cancer Chemother Pharmacol 2013; 71: 1051-1057.
    • (2013) Cancer Chemother Pharmacol , vol.71 , pp. 1051-1057
    • Bisagni, G.1    Musolino, A.2    Panebianco, M.3    De Matteis, A.4    Nuzzo, F.5    Ardizzoni, A.6    Gori, S.7    Gamucci, T.8    Passalacqua, R.9    Gnoni, R.10    Moretti, G.11    Boni, C.12
  • 37
    • 84873095858 scopus 로고    scopus 로고
    • Bevacizumab plus paclitaxel versus bevacizumab plus capecitabine as first-line treatment for HER2-negative metastatic breast cancer: Interim efficacy results of the randomised, open-label, non-inferiority, phase 3 TURANDOT trial
    • Central European Cooperative Oncology Group
    • Lang I, Brodowicz T, Ryvo L, Kahan Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Zvirbule Z, Steger GG, Melichar B, Pienkowski T, Sirbu D, Messinger D, Zielinski C; Central European Cooperative Oncology Group. Bevacizumab plus paclitaxel versus bevacizumab plus capecitabine as first-line treatment for HER2-negative metastatic breast cancer: interim efficacy results of the randomised, open-label, non-inferiority, phase 3 TURANDOT trial. Lancet Oncol 2013; 14: 125-133.
    • (2013) Lancet Oncol , vol.14 , pp. 125-133
    • Lang, I.1    Brodowicz, T.2    Ryvo, L.3    Kahan, Z.4    Greil, R.5    Beslija, S.6    Stemmer, S.M.7    Kaufman, B.8    Zvirbule, Z.9    Steger, G.G.10    Melichar, B.11    Pienkowski, T.12    Sirbu, D.13    Messinger, D.14    Zielinski, C.15
  • 40
    • 84868206358 scopus 로고    scopus 로고
    • Safety results from a phase III study (TURANDOT trial by CECOG) of first-line bevacizumab in combination with capecitabine or paclitaxel for HER-2-negative locally recurrent or metastatic breast cancer
    • Lang I, Inbar MJ, Kahan Z, Greil R, Beslija S, Stemmer SM, Kaufman B, Zvirbule Z, Steger GG, Messinger D, Brodowicz T and Zielinski C. Safety results from a phase III study (TURANDOT trial by CECOG) of first-line bevacizumab in combination with capecitabine or paclitaxel for HER-2-negative locally recurrent or metastatic breast cancer. Eur J Cancer 2012; 48: 3140-3149.
    • (2012) Eur J Cancer , vol.48 , pp. 3140-3149
    • Lang, I.1    Inbar, M.J.2    Kahan, Z.3    Greil, R.4    Beslija, S.5    Stemmer, S.M.6    Kaufman, B.7    Zvirbule, Z.8    Steger, G.G.9    Messinger, D.10    Brodowicz, T.11    Zielinski, C.12
  • 41
    • 84872956413 scopus 로고    scopus 로고
    • A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma: A North Central Cancer Treatment Group study, N0775
    • Kottschade LA, Suman VJ, Perez DG, McWilliams RR, Kaur JS, Amatruda TT 3rd, Geoffroy FJ, Gross HM, Cohen PA, Jaslowski AJ, Kosel ML and Markovic SN. A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma: a North Central Cancer Treatment Group study, N0775. Cancer 2013; 119: 586-592.
    • (2013) Cancer , vol.119 , pp. 586-592
    • Kottschade, L.A.1    Suman, V.J.2    Perez, D.G.3    McWilliams, R.R.4    Kaur, J.S.5    Amatruda, T.T.6    Geoffroy, F.J.7    Gross, H.M.8    Cohen, P.A.9    Jaslowski, A.J.10    Kosel, M.L.11    Markovic, S.N.12
  • 42
  • 43
    • 84878832178 scopus 로고    scopus 로고
    • Bevacizumab and erlotinib in previously untreated inoperable and metastatic hepatocellular carcinoma
    • Govindarajan R, Siegel E, Makhoul I and Williamson S. Bevacizumab and erlotinib in previously untreated inoperable and metastatic hepatocellular carcinoma. Am J Clin Oncol 2013; 36: 254-257.
    • (2013) Am J Clin Oncol , vol.36 , pp. 254-257
    • Govindarajan, R.1    Siegel, E.2    Makhoul, I.3    Williamson, S.4
  • 45
    • 84875543408 scopus 로고    scopus 로고
    • Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease
    • Yau T, Wong H, Chan P, Yao TJ, Pang R, Cheung TT, Fan ST and Poon RT. Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease. Invest New Drugs 2012; 30: 2384-2390.
    • (2012) Invest New Drugs , vol.30 , pp. 2384-2390
    • Yau, T.1    Wong, H.2    Chan, P.3    Yao, T.J.4    Pang, R.5    Cheung, T.T.6    Fan, S.T.7    Poon, R.T.8
  • 47
    • 84868123504 scopus 로고    scopus 로고
    • VEGF remains an interesting target in advanced pancreas cancer (APCA): Results of a multi-institutional phase II study of bevacizumab, gemcitabine, and infusional 5-fluorouracil in patients with APCA
    • Martin LK, Li X, Kleiber B, Ellison EC, Bloomston M, Zalupski M and Bekaii-Saab TS. VEGF remains an interesting target in advanced pancreas cancer (APCA): results of a multi-institutional phase II study of bevacizumab, gemcitabine, and infusional 5-fluorouracil in patients with APCA. Ann Oncol 2012; 23: 2812-2820.
    • (2012) Ann Oncol , vol.23 , pp. 2812-2820
    • Martin, L.K.1    Li, X.2    Kleiber, B.3    Ellison, E.C.4    Bloomston, M.5    Zalupski, M.6    Bekaii-Saab, T.S.7
  • 50
    • 84876256993 scopus 로고    scopus 로고
    • Weekly administration of bevacizumab, gemcitabine, and oxaliplatin in patients with recurrent and refractory ovarian cancer: A preliminary result of 19 cases
    • Ikeda Y, Takano M, Oda K, Kouta H, Goto T, Kudoh K, Sasaki N, Kita T and Kikuchi Y. Weekly administration of bevacizumab, gemcitabine, and oxaliplatin in patients with recurrent and refractory ovarian cancer: a preliminary result of 19 cases. Int J Gynecol Cancer 2013; 23: 355-360.
    • (2013) Int J Gynecol Cancer , vol.23 , pp. 355-360
    • Ikeda, Y.1    Takano, M.2    Oda, K.3    Kouta, H.4    Goto, T.5    Kudoh, K.6    Sasaki, N.7    Kita, T.8    Kikuchi, Y.9
  • 51
    • 84872835463 scopus 로고    scopus 로고
    • Phase II clinical trial of bevacizumab with albumin-bound paclitaxel in patients with recurrent, platinum-resistant primary epithelial ovarian or primary peritoneal carcinoma
    • Tillmanns TD, Lowe MP, Walker MS, Stepanski EJ and Schwartzberg LS. Phase II clinical trial of bevacizumab with albumin-bound paclitaxel in patients with recurrent, platinum-resistant primary epithelial ovarian or primary peritoneal carcinoma. Gynecol Oncol 2013; 128: 221-228.
    • (2013) Gynecol Oncol , vol.128 , pp. 221-228
    • Tillmanns, T.D.1    Lowe, M.P.2    Walker, M.S.3    Stepanski, E.J.4    Schwartzberg, L.S.5
  • 56
    • 84867551535 scopus 로고    scopus 로고
    • Phase I study of the antiangiogenic antibody bevacizumab and the mTOR/hypoxia-inducible factor inhibitor temsirolimus combined with liposomal doxorubicin: Tolerance and biological activity
    • Moroney J, Fu S, Moulder S, Falchook G, Helgason T, Levenback C, Hong D, Naing A, Wheler J and Kurzrock R. Phase I study of the antiangiogenic antibody bevacizumab and the mTOR/hypoxia-inducible factor inhibitor temsirolimus combined with liposomal doxorubicin: tolerance and biological activity. Clin Cancer Res 2012; 18: 5796-5805.
    • (2012) Clin Cancer Res , vol.18 , pp. 5796-5805
    • Moroney, J.1    Fu, S.2    Moulder, S.3    Falchook, G.4    Helgason, T.5    Levenback, C.6    Hong, D.7    Naing, A.8    Wheler, J.9    Kurzrock, R.10
  • 60
    • 84903730020 scopus 로고    scopus 로고
    • Long-term remission of a Her2/neu positive primary breast cancer under double monoclonal antibody therapy with trastuzumab and bevacizumab
    • Konigsberg R, Maierhofer J, Steininger T, Kienzer G and Dittrich C. Long-term remission of a Her2/neu positive primary breast cancer under double monoclonal antibody therapy with trastuzumab and bevacizumab. Radiol Oncol 2014; 48: 184-188.
    • (2014) Radiol Oncol , vol.48 , pp. 184-188
    • Konigsberg, R.1    Maierhofer, J.2    Steininger, T.3    Kienzer, G.4    Dittrich, C.5
  • 62
    • 81155123190 scopus 로고    scopus 로고
    • RIBBON-2: A randomized, double-blind, placebo-controlled, phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
    • Brufsky AM, Hurvitz S, Perez E, Swamy R, Valero V, O’Neill V and Rugo HS. RIBBON-2: a randomized, double-blind, placebo-controlled, phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 2011; 29: 4286-4293.
    • (2011) J Clin Oncol , vol.29 , pp. 4286-4293
    • Brufsky, A.M.1    Hurvitz, S.2    Perez, E.3    Swamy, R.4    Valero, V.5    O’Neill, V.6    Rugo, H.S.7
  • 63
    • 79953874259 scopus 로고    scopus 로고
    • RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer
    • Robert NJ, Dieras V, Glaspy J, Brufsky AM, Bondarenko I, Lipatov ON, Perez EA, Yardley DA, Chan SY, Zhou X, Phan SC and O’Shaughnessy J. RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancer. J Clin Oncol 2011; 29: 1252-1260.
    • (2011) J Clin Oncol , vol.29 , pp. 1252-1260
    • Robert, N.J.1    Dieras, V.2    Glaspy, J.3    Brufsky, A.M.4    Bondarenko, I.5    Lipatov, O.N.6    Perez, E.A.7    Yardley, D.A.8    Chan, S.Y.9    Zhou, X.10    Phan, S.C.11    O’Shaughnessy, J.12
  • 64
    • 84901979851 scopus 로고    scopus 로고
    • Toxicity of targeted therapy: Implications for response and impact of genetic polymorphisms
    • Liu S and Kurzrock R. Toxicity of targeted therapy: Implications for response and impact of genetic polymorphisms. Cancer Treat Rev 2014; 40: 883-891.
    • (2014) Cancer Treat Rev , vol.40 , pp. 883-891
    • Liu, S.1    Kurzrock, R.2
  • 66
    • 34249294557 scopus 로고    scopus 로고
    • Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition
    • Verheul HM and Pinedo HM. Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Nat Rev Cancer 2007; 7: 475-485.
    • (2007) Nat Rev Cancer , vol.7 , pp. 475-485
    • Verheul, H.M.1    Pinedo, H.M.2
  • 67
    • 73449122638 scopus 로고    scopus 로고
    • Managing bevacizumab-related toxicities in patients with colorectal cancer
    • Saif MW. Managing bevacizumab-related toxicities in patients with colorectal cancer. J Support Oncol 2009; 7: 245-251.
    • (2009) J Support Oncol , vol.7 , pp. 245-251
    • Saif, M.W.1
  • 68
    • 67650173972 scopus 로고    scopus 로고
    • Hypothyroidism related to tyrosine kinase inhibitors: An emerging toxic effect of targeted therapy
    • Torino F, Corsello SM, Longo R, Barnabei A and Gasparini G. Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy. Nat Rev Clin Oncol 2009; 6: 219-228.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 219-228
    • Torino, F.1    Corsello, S.M.2    Longo, R.3    Barnabei, A.4    Gasparini, G.5
  • 69
    • 77951879926 scopus 로고    scopus 로고
    • Antiangiogenic drugs in oncology: A focus on drug safety and the elderly-a mini-review
    • Boehm S, Rothermundt C, Hess D and Joerger M. Antiangiogenic drugs in oncology: a focus on drug safety and the elderly-a mini-review. Gerontology 2010; 56: 303-309.
    • (2010) Gerontology , vol.56 , pp. 303-309
    • Boehm, S.1    Rothermundt, C.2    Hess, D.3    Joerger, M.4
  • 71
    • 84892735302 scopus 로고    scopus 로고
    • Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations
    • Lindholm EM, Krohn M, Iadevaia S, Kristian A, Mills GB, Maelandsmo GM and Engebraaten O. Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations. Clin Cancer Res 2014; 20: 404-412.
    • (2014) Clin Cancer Res , vol.20 , pp. 404-412
    • Lindholm, E.M.1    Krohn, M.2    Iadevaia, S.3    Kristian, A.4    Mills, G.B.5    Maelandsmo, G.M.6    Engebraaten, O.7
  • 72
    • 84903124276 scopus 로고    scopus 로고
    • Targeting multiple angiogenic pathways simultaneously: Experience with nintedanib in non-small-cell lung cancer
    • Durm G and Hanna N. Targeting multiple angiogenic pathways simultaneously: experience with nintedanib in non-small-cell lung cancer. Future Oncol 2014; 10: 1167-1173.
    • (2014) Future Oncol , vol.10 , pp. 1167-1173
    • Durm, G.1    Hanna, N.2
  • 74
    • 30944446883 scopus 로고    scopus 로고
    • Lessons from phase III clinical trials on anti-VEGF therapy for cancer
    • Jain RK, Duda DG, Clark JW and Loeffler JS. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 2006; 3: 24-40.
    • (2006) Nat Clin Pract Oncol , vol.3 , pp. 24-40
    • Jain, R.K.1    Duda, D.G.2    Clark, J.W.3    Loeffler, J.S.4
  • 75
    • 67650674112 scopus 로고    scopus 로고
    • Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer
    • Krupitskaya Y and Wakelee HA. Ramucirumab, a fully human mAb to the transmembrane signaling tyrosine kinase VEGFR-2 for the potential treatment of cancer. Curr Opin Investig Drugs 2009; 10: 597-605.
    • (2009) Curr Opin Investig Drugs , vol.10 , pp. 597-605
    • Krupitskaya, Y.1    Wakelee, H.A.2
  • 78
    • 84867503535 scopus 로고    scopus 로고
    • A randomized, doubleblind, phase III study of Docetaxel and Ramucirumab versus Docetaxel and placebo in the treatment of stage IV non-small-cell lung cancer after disease progression after 1 previous platinum-based therapy (REVEL): Treatment rationale and study design
    • Garon EB, Cao D, Alexandris E, John WJ, Yurasov S and Perol M. A randomized, doubleblind, phase III study of Docetaxel and Ramucirumab versus Docetaxel and placebo in the treatment of stage IV non-small-cell lung cancer after disease progression after 1 previous platinum-based therapy (REVEL): treatment rationale and study design. Clin Lung Cancer 2012; 13: 505-509.
    • (2012) Clin Lung Cancer , vol.13 , pp. 505-509
    • Garon, E.B.1    Cao, D.2    Alexandris, E.3    John, W.J.4    Yurasov, S.5    Perol, M.6
  • 79
    • 77952673621 scopus 로고    scopus 로고
    • Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates
    • Loges S, Schmidt T and Carmeliet P. Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates. Genes Cancer 2010; 1: 12-25.
    • (2010) Genes Cancer , vol.1 , pp. 12-25
    • Loges, S.1    Schmidt, T.2    Carmeliet, P.3
  • 80
    • 84876993950 scopus 로고    scopus 로고
    • Normalizing tumor microenvironment to treat cancer: Bench to bedside to biomarkers
    • Jain RK. Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers. J Clin Oncol 2013; 31: 2205-2218.
    • (2013) J Clin Oncol , vol.31 , pp. 2205-2218
    • Jain, R.K.1
  • 81
    • 0033205573 scopus 로고    scopus 로고
    • The role of the vascular phase in solid tumor growth: A historical review
    • Ribatti D, Vacca A and Dammacco F. The role of the vascular phase in solid tumor growth: a historical review. Neoplasia 1999; 1: 293-302.
    • (1999) Neoplasia , vol.1 , pp. 293-302
    • Ribatti, D.1    Vacca, A.2    Dammacco, F.3
  • 83
    • 0007565652 scopus 로고
    • Amsterdam: Martinus Nijhoff Publishing
    • Folkman J. Angiogenesis. Amsterdam: Martinus Nijhoff Publishing; 1984.
    • (1984) Angiogenesis
    • Folkman, J.1
  • 84
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D and Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 85
    • 0142089891 scopus 로고    scopus 로고
    • New nonangiogenesis dependent pathways for tumour growth
    • Ribatti D, Vacca A and Dammacco F. New nonangiogenesis dependent pathways for tumour growth. Eur J Cancer 2003; 39: 1835-1841.
    • (2003) Eur J Cancer , vol.39 , pp. 1835-1841
    • Ribatti, D.1    Vacca, A.2    Dammacco, F.3
  • 91
    • 0035150823 scopus 로고    scopus 로고
    • Lymphangiogenesis in malignant tumours: Does it occur?
    • Clarijs R, Ruiter DJ and de Waal RM. Lymphangiogenesis in malignant tumours: Does it occur? J Pathol 2001; 193: 143-146.
    • (2001) J Pathol , vol.193 , pp. 143-146
    • Clarijs, R.1    Ruiter, D.J.2    De Waal, R.M.3
  • 92
    • 0036310316 scopus 로고    scopus 로고
    • The role of tumor lymphangiogenesis in metastatic spread
    • Stacker SA, Baldwin ME and Achen MG. The role of tumor lymphangiogenesis in metastatic spread. FASEB J 2002; 16: 922-934.
    • (2002) FASEB J , vol.16 , pp. 922-934
    • Stacker, S.A.1    Baldwin, M.E.2    Achen, M.G.3
  • 93
    • 80052666824 scopus 로고    scopus 로고
    • Contribution of cancer stem cells to tumor vasculogenic mimicry
    • Yao XH, Ping YF and Bian XW. Contribution of cancer stem cells to tumor vasculogenic mimicry. Protein Cell 2011; 2: 266-272.
    • (2011) Protein Cell , vol.2 , pp. 266-272
    • Yao, X.H.1    Ping, Y.F.2    Bian, X.W.3
  • 94
    • 84873409223 scopus 로고    scopus 로고
    • CD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triplenegative breast cancer
    • Liu TJ, Sun BC, Zhao XL, Zhao XM, Sun T, Gu Q, Yao Z, Dong XY, Zhao N and Liu N. CD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triplenegative breast cancer. Oncogene 2013; 32: 544-553.
    • (2013) Oncogene , vol.32 , pp. 544-553
    • Liu, T.J.1    Sun, B.C.2    Zhao, X.L.3    Zhao, X.M.4    Sun, T.5    Gu, Q.6    Yao, Z.7    Dong, X.Y.8    Zhao, N.9    Liu, N.10
  • 95
    • 79957625759 scopus 로고    scopus 로고
    • Consice review: Contribution of cancer stem cells to neovascularization
    • Ping YF and Bian XW. Consice review: Contribution of cancer stem cells to neovascularization. Stem Cells 2011; 29: 888-894.
    • (2011) Stem Cells , vol.29 , pp. 888-894
    • Ping, Y.F.1    Bian, X.W.2
  • 97
    • 84874981793 scopus 로고    scopus 로고
    • Inherent phenotypic plasticity fa cilitates progression of head and neck cancer: Endotheliod characteristics enable angiogenesis and invasion
    • Tong M, Han BB, Holpuch AS, Pei P, He L and Mallery SR. Inherent phenotypic plasticity fa cilitates progression of head and neck cancer: endotheliod characteristics enable angiogenesis and invasion. Exp Cell Res 2013; 319: 1028-1042.
    • (2013) Exp Cell Res , vol.319 , pp. 1028-1042
    • Tong, M.1    Han, B.B.2    Holpuch, A.S.3    Pei, P.4    He, L.5    Mallery, S.R.6
  • 98
    • 79955602691 scopus 로고    scopus 로고
    • Trophoblastic vasculogenic mimicry in gestational choriocarcinoma
    • Shih IeM. Trophoblastic vasculogenic mimicry in gestational choriocarcinoma. Mod Pathol 2011; 24: 646-652.
    • (2011) Mod Pathol , vol.24 , pp. 646-652
    • Shih, I.1
  • 99
    • 0344080490 scopus 로고    scopus 로고
    • Inflammatory breast cancer: Vasculogenic mimicry and its hemodynamics of an inflammatory breast cancer xenograft model
    • Shirakawa K, Kobayashi H, Sobajima J, Hashimoto D, Shimizu A and Wakasugi H. Inflammatory breast cancer: vasculogenic mimicry and its hemodynamics of an inflammatory breast cancer xenograft model. Breast Cancer Res 2003; 5: 136-139.
    • (2003) Breast Cancer Res , vol.5 , pp. 136-139
    • Shirakawa, K.1    Kobayashi, H.2    Sobajima, J.3    Hashimoto, D.4    Shimizu, A.5    Wakasugi, H.6
  • 100
    • 37349055797 scopus 로고    scopus 로고
    • A pilot study of vasculogenic mimicry immunohistochemical expression in hepatocellular carcinoma
    • Guzman G, Cotler SJ, Lin AY, Maniotis AJ and Folberg R. A pilot study of vasculogenic mimicry immunohistochemical expression in hepatocellular carcinoma. Arch Pathol Lab Med 2007; 131: 1776-1781.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 1776-1781
    • Guzman, G.1    Cotler, S.J.2    Lin, A.Y.3    Maniotis, A.J.4    Folberg, R.5
  • 102
    • 84874890917 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor 2 (VEGFR-2) plays a key role in vasculogenic mimicry formation, neovascularization and tumor initiation by Glioma stemlike cells
    • Yao X, Ping Y, Liu Y, Chen K, Yoshimura T, Liu M, Gong W, Chen C, Niu Q, Guo D, Zhang X, Wang JM and Bian X. Vascular endothelial growth factor receptor 2 (VEGFR-2) plays a key role in vasculogenic mimicry formation, neovascularization and tumor initiation by Glioma stemlike cells. PLoS One 2013; 8: e57188.
    • (2013) Plos One , vol.8
    • Yao, X.1    Ping, Y.2    Liu, Y.3    Chen, K.4    Yoshimura, T.5    Liu, M.6    Gong, W.7    Chen, C.8    Niu, Q.9    Guo, D.10    Zhang, X.11    Wang, J.M.12    Bian, X.13
  • 104
    • 84879601170 scopus 로고    scopus 로고
    • Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme
    • Soda Y, Myskiw C, Rommel A and Verma IM. Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme. J Mol Med (Berl) 2013; 91: 439-448.
    • (2013) J Mol Med (Berl) , vol.91 , pp. 439-448
    • Soda, Y.1    Myskiw, C.2    Rommel, A.3    Verma, I.M.4
  • 112
    • 84943231185 scopus 로고    scopus 로고
    • Wnt-b-Catenin Pathway Regulates Vascular Mimicry in Triple Negative Breast Cancer
    • [Epub ahead of print]
    • De P, Carlson J, Leyland-Jones B and Dey N. Wnt-b-Catenin Pathway Regulates Vascular Mimicry in Triple Negative Breast Cancer. Journal of Cytology & Histology 2013; [Epub ahead of print].
    • (2013) Journal of Cytology & Histology
    • De, P.1    Carlson, J.2    Leyland-Jones, B.3    Dey, N.4
  • 114
    • 84885451161 scopus 로고    scopus 로고
    • Differential Activation of Wnt-b-Catenin Pathway in Triple Negative Breast Cancer Increases MMP7 in a PTEN Dependent Manner
    • Dey N, Young B, Abramovitz M, Bouzyk M, Barwick B, De P and Leyland-Jones B. Differential Activation of Wnt-b-Catenin Pathway in Triple Negative Breast Cancer Increases MMP7 in a PTEN Dependent Manner. PLos One 2013; 8: e77425.
    • (2013) Plos One , vol.8
    • Dey, N.1    Young, B.2    Abramovitz, M.3    Bouzyk, M.4    Barwick, B.5    De, P.6    Leyland-Jones, B.7
  • 116
    • 77951498489 scopus 로고    scopus 로고
    • Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis
    • Ferrara N. Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis. Curr Opin Hematol 2010; 17: 219-224.
    • (2010) Curr Opin Hematol , vol.17 , pp. 219-224
    • Ferrara, N.1
  • 117
    • 66349093990 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • Ferrara N. Vascular endothelial growth factor. Arterioscler Thromb Vasc Biol 2009; 29: 789-791.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 789-791
    • Ferrara, N.1
  • 119
    • 77549088772 scopus 로고    scopus 로고
    • Pathways mediating VEGFindependent tumor angiogenesis
    • Ferrara N. Pathways mediating VEGFindependent tumor angiogenesis. Cytokine Growth Factor Rev 2010; 21: 21-26.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 21-26
    • Ferrara, N.1
  • 120
    • 34548443831 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2: Structure, function, intracellular signalling and therapeutic inhibition
    • Holmes K, Roberts OL, Thomas AM and Cross MJ. Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition. Cell Signal 2007; 19: 2003-2012.
    • (2007) Cell Signal , vol.19 , pp. 2003-2012
    • Holmes, K.1    Roberts, O.L.2    Thomas, A.M.3    Cross, M.J.4
  • 124
    • 82155203054 scopus 로고    scopus 로고
    • Biomarkers predicting tumor response and evasion to anti-angiogenic therapy
    • Jahangiri A and Aghi MK. Biomarkers predicting tumor response and evasion to anti-angiogenic therapy. Biochim Biophys Acta 2012; 1825: 86-100.
    • (2012) Biochim Biophys Acta , vol.1825 , pp. 86-100
    • Jahangiri, A.1    Aghi, M.K.2
  • 125
    • 70449635893 scopus 로고    scopus 로고
    • Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies
    • Crawford Y and Ferrara N. Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies. Trends Pharmacol Sci 2009; 30: 624-630.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 624-630
    • Crawford, Y.1    Ferrara, N.2
  • 126
    • 55949096784 scopus 로고    scopus 로고
    • Role of the microenvironment in tumor growth and in refractoriness/ resistance to anti-angiogenic therapies
    • Shojaei F and Ferrara N. Role of the microenvironment in tumor growth and in refractoriness/ resistance to anti-angiogenic therapies. Drug Resist Updat 2008; 11: 219-230.
    • (2008) Drug Resist Updat , vol.11 , pp. 219-230
    • Shojaei, F.1    Ferrara, N.2
  • 127
    • 84884196348 scopus 로고    scopus 로고
    • Dynamic Quantitative Intravital Imaging of Glioblastoma Progression Reveals a Lack of Correlation between Tumor Growth and Blood Vessel Density
    • Ricard C, Stanchi F, Rodriguez T, Amoureux MC, Rougon G and Debarbieux F. Dynamic Quantitative Intravital Imaging of Glioblastoma Progression Reveals a Lack of Correlation between Tumor Growth and Blood Vessel Density. PLoS One 2013; 8: e72655.
    • (2013) Plos One , vol.8
    • Ricard, C.1    Stanchi, F.2    Rodriguez, T.3    Amoureux, M.C.4    Rougon, G.5    Debarbieux, F.6
  • 128
    • 74949105013 scopus 로고    scopus 로고
    • Biomarkers of antiangiogenic therapy: How do we move from candidate biomarkers to valid biomarkers?
    • Duda DG, Ancukiewicz M and Jain RK. Biomarkers of antiangiogenic therapy: how do we move from candidate biomarkers to valid biomarkers? J Clin Oncol 2010; 28: 183-185.
    • (2010) J Clin Oncol , vol.28 , pp. 183-185
    • Duda, D.G.1    Ancukiewicz, M.2    Jain, R.K.3
  • 130
    • 84930695689 scopus 로고    scopus 로고
    • Reactive resistance to anti-angiogenic drugs
    • Bousquet G and Janin A. Reactive resistance to anti-angiogenic drugs. Aging (Albany NY) 2015; 7: 282-283.
    • (2015) Aging (Albany NY) , vol.7 , pp. 282-283
    • Bousquet, G.1    Janin, A.2
  • 131
    • 36749052895 scopus 로고    scopus 로고
    • Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
    • Ebos JM, Lee CR, Christensen JG, Mutsaers AJ and Kerbel RS. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy. Proc Natl Acad Sci U S A 2007; 104: 17069-17074.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17069-17074
    • Ebos, J.M.1    Lee, C.R.2    Christensen, J.G.3    Mutsaers, A.J.4    Kerbel, R.S.5
  • 133
    • 84947719981 scopus 로고    scopus 로고
    • Evolution of Tumor Model: From Animal Model of Tumor to Tumor Model in Animal
    • Dey N, Leyland-Jones B and De P. Evolution of Tumor Model: From Animal Model of Tumor to Tumor Model in Animal. Journal of Cancer Therapy 2013; 4: 1411-1425.
    • (2013) Journal of Cancer Therapy , vol.4 , pp. 1411-1425
    • Dey, N.1    Leyland-Jones, B.2    De, P.3
  • 137
    • 66149092730 scopus 로고    scopus 로고
    • G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models
    • Shojaei F, Wu X, Qu X, Kowanetz M, Yu L, Tan M, Meng YG and Ferrara N. G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Proc Natl Acad Sci U S A 2009; 106: 6742-6747.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 6742-6747
    • Shojaei, F.1    Wu, X.2    Qu, X.3    Kowanetz, M.4    Yu, L.5    Tan, M.6    Meng, Y.G.7    Ferrara, N.8
  • 138
    • 65249191418 scopus 로고    scopus 로고
    • Characterization and regulation of bv8 in human blood cells
    • Zhong C, Qu X, Tan M, Meng YG and Ferrara N. Characterization and regulation of bv8 in human blood cells. Clin Cancer Res 2009; 15: 2675-2684.
    • (2009) Clin Cancer Res , vol.15 , pp. 2675-2684
    • Zhong, C.1    Qu, X.2    Tan, M.3    Meng, Y.G.4    Ferrara, N.5
  • 139
    • 69249153469 scopus 로고    scopus 로고
    • Etiology and outcome of extreme leukocytosis in 758 nonhematologic cancer patients: A retrospective, single-institution study
    • Granger JM and Kontoyiannis DP. Etiology and outcome of extreme leukocytosis in 758 nonhematologic cancer patients: a retrospective, single-institution study. Cancer 2009; 115: 3919-3923.
    • (2009) Cancer , vol.115 , pp. 3919-3923
    • Granger, J.M.1    Kontoyiannis, D.P.2
  • 140
    • 73349110110 scopus 로고    scopus 로고
    • Rapid clinical deterioration and leukemoid reaction after treatment of urothelial carcinoma of the bladder: Possible effect of granulocyte colony-stimulating factor
    • Perez FA, Fligner CL and Yu EY. Rapid clinical deterioration and leukemoid reaction after treatment of urothelial carcinoma of the bladder: possible effect of granulocyte colony-stimulating factor. J Clin Oncol 2009; 27: e215-e217.
    • (2009) J Clin Oncol , vol.27 , pp. e215-e217
    • Perez, F.A.1    Fligner, C.L.2    Yu, E.Y.3
  • 143
    • 57849117839 scopus 로고    scopus 로고
    • Tumor-associated fibroblasts as “Trojan Horse” mediators of resistance to anti-VEGF therapy
    • Francia G, Emmenegger U and Kerbel RS. Tumor-associated fibroblasts as “Trojan Horse” mediators of resistance to anti-VEGF therapy. Cancer Cell 2009; 15: 3-5.
    • (2009) Cancer Cell , vol.15 , pp. 3-5
    • Francia, G.1    Emmenegger, U.2    Kerbel, R.S.3
  • 144
    • 57849106330 scopus 로고    scopus 로고
    • PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment
    • Crawford Y, Kasman I, Yu L, Zhong C, Wu X, Modrusan Z, Kaminker J and Ferrara N. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell 2009; 15: 21-34.
    • (2009) Cancer Cell , vol.15 , pp. 21-34
    • Crawford, Y.1    Kasman, I.2    Yu, L.3    Zhong, C.4    Wu, X.5    Modrusan, Z.6    Kaminker, J.7    Ferrara, N.8


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