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Volumn 6, Issue 33, 2015, Pages 34071-34086

Effects of a novel Nodal-targeting monoclonal antibody in melanoma

Author keywords

Antibody; Cancer; ELISA; Nodal; Therapy

Indexed keywords

B RAF KINASE; CYCLIN B1; DABRAFENIB; HISTONE H3; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 3D1; PROTEIN NODAL; PROTEIN P27; SMAD2 PROTEIN; UNCLASSIFIED DRUG; CCNB1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; IMIDAZOLE DERIVATIVE; NODAL PROTEIN, HUMAN; OXIME; SMAD2 PROTEIN, HUMAN;

EID: 84941222229     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6049     Document Type: Article
Times cited : (22)

References (53)
  • 2
    • 33846682938 scopus 로고    scopus 로고
    • Chemotherapy for metastatic melanoma: time for a change?
    • Gogas HJ, Kirkwood JM and Sondak VK. Chemotherapy for metastatic melanoma: time for a change? Cancer. 2007; 109:455-464.
    • (2007) Cancer , vol.109 , pp. 455-464
    • Gogas, H.J.1    Kirkwood, J.M.2    Sondak, V.K.3
  • 13
    • 84879679714 scopus 로고    scopus 로고
    • Advances in personalized targeted treatment of metastatic melanoma and non-invasive tumor monitoring
    • Klinac D, Gray ES, Millward M and Ziman M. Advances in personalized targeted treatment of metastatic melanoma and non-invasive tumor monitoring. Front Oncol. 2013; 3:54.
    • (2013) Front Oncol , vol.3 , pp. 54
    • Klinac, D.1    Gray, E.S.2    Millward, M.3    Ziman, M.4
  • 14
    • 84930541641 scopus 로고    scopus 로고
    • Tumor heterogeneity and plasticity as elusive drivers for resistance to MAPK pathway inhibition in melanoma
    • Roesch A. Tumor heterogeneity and plasticity as elusive drivers for resistance to MAPK pathway inhibition in melanoma. Oncogene. 2015; 34:2951-2957.
    • (2015) Oncogene , vol.34 , pp. 2951-2957
    • Roesch, A.1
  • 15
    • 84924055386 scopus 로고    scopus 로고
    • Immunotherapies and novel combinations: the focus of advances in the treatment of melanoma
    • Ascierto PA. Immunotherapies and novel combinations: the focus of advances in the treatment of melanoma. Cancer Immunol Immunother. 2015; 64:271-274.
    • (2015) Cancer Immunol Immunother , vol.64 , pp. 271-274
    • Ascierto, P.A.1
  • 16
    • 33745075558 scopus 로고    scopus 로고
    • Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases
    • Smalley KS, Haass NK, Brafford PA, Lioni M, Flaherty KT and Herlyn M. Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Mol Cancer Ther. 2006; 5:1136-1144.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1136-1144
    • Smalley, K.S.1    Haass, N.K.2    Brafford, P.A.3    Lioni, M.4    Flaherty, K.T.5    Herlyn, M.6
  • 18
    • 33947656333 scopus 로고    scopus 로고
    • Nodal signaling: developmental roles and regulation
    • Shen MM. Nodal signaling: developmental roles and regulation. Development. 2007; 134:1023-1034.
    • (2007) Development , vol.134 , pp. 1023-1034
    • Shen, M.M.1
  • 31
    • 84911866508 scopus 로고    scopus 로고
    • The melanoma revolution: from UV carcinogenesis to a new era in therapeutics
    • Lo JA and Fisher DE. The melanoma revolution: from UV carcinogenesis to a new era in therapeutics. Science. 2014; 346:945-949.
    • (2014) Science , vol.346 , pp. 945-949
    • Lo, J.A.1    Fisher, D.E.2
  • 34
    • 14244262504 scopus 로고    scopus 로고
    • Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway
    • Vallier L, Reynolds D and Pedersen RA. Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway. Dev Biol. 2004; 275:403-421.
    • (2004) Dev Biol , vol.275 , pp. 403-421
    • Vallier, L.1    Reynolds, D.2    Pedersen, R.A.3
  • 36
    • 84897020005 scopus 로고    scopus 로고
    • Nodal promotes invasive phenotypes via a mitogenactivated protein kinase-dependent pathway
    • Quail DF, Zhang G, Findlay SD, Hess DA and Postovit LM. Nodal promotes invasive phenotypes via a mitogenactivated protein kinase-dependent pathway. Oncogene. 2014; 33:461-473.
    • (2014) Oncogene , vol.33 , pp. 461-473
    • Quail, D.F.1    Zhang, G.2    Findlay, S.D.3    Hess, D.A.4    Postovit, L.M.5
  • 40
    • 84969670068 scopus 로고    scopus 로고
    • Essential dynamics analysis captures the concerted motion of the integrinbinding site in jerdostatin, an RTS disintegrin
    • Calvanese L, Falcigno L and D'Auria G. Essential dynamics analysis captures the concerted motion of the integrinbinding site in jerdostatin, an RTS disintegrin. Biopolymers. 2015; 103:158-166.
    • (2015) Biopolymers , vol.103 , pp. 158-166
    • Calvanese, L.1    Falcigno, L.2    D'Auria, G.3
  • 41
    • 84878432797 scopus 로고    scopus 로고
    • Experience in daily practice with ipilimumab for the treatment of patients with metastatic melanoma: an early increase in lymphocyte and eosinophil counts is associated with improved survival
    • Delyon J, Mateus C, Lefeuvre D, Lanoy E, Zitvogel L, Chaput N, Roy S, Eggermont AM, Routier E and Robert C. Experience in daily practice with ipilimumab for the treatment of patients with metastatic melanoma: an early increase in lymphocyte and eosinophil counts is associated with improved survival. Ann Oncol. 2013; 24:1697-1703.
    • (2013) Ann Oncol , vol.24 , pp. 1697-1703
    • Delyon, J.1    Mateus, C.2    Lefeuvre, D.3    Lanoy, E.4    Zitvogel, L.5    Chaput, N.6    Roy, S.7    Eggermont, A.M.8    Routier, E.9    Robert, C.10
  • 42
    • 0025944815 scopus 로고
    • Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors
    • Johnsson B, Lofas S and Lindquist G. Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors. Anal Biochem. 1991; 198:268-277.
    • (1991) Anal Biochem , vol.198 , pp. 268-277
    • Johnsson, B.1    Lofas, S.2    Lindquist, G.3
  • 44
    • 78650334835 scopus 로고    scopus 로고
    • Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype
    • Hardy KM, Kirschmann DA, Seftor EA, Margaryan NV, Postovit LM, Strizzi L and Hendrix MJ. Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype. Cancer Res. 2010; 70:10340-10350.
    • (2010) Cancer Res , vol.70 , pp. 10340-10350
    • Hardy, K.M.1    Kirschmann, D.A.2    Seftor, E.A.3    Margaryan, N.V.4    Postovit, L.M.5    Strizzi, L.6    Hendrix, M.J.7
  • 45
    • 0021237842 scopus 로고
    • A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice
    • Kozlowski JM, Hart IR, Fidler IJ and Hanna N. A human melanoma line heterogeneous with respect to metastatic capacity in athymic nude mice. J Natl Cancer Inst. 1984; 72:913-917.
    • (1984) J Natl Cancer Inst , vol.72 , pp. 913-917
    • Kozlowski, J.M.1    Hart, I.R.2    Fidler, I.J.3    Hanna, N.4
  • 48
  • 50
    • 80052730839 scopus 로고    scopus 로고
    • Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells
    • Fu G, Peng C. Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells. Oncogene. 2011; 30:3953-66.
    • (2011) Oncogene , vol.30 , pp. 3953-3966
    • Fu, G.1    Peng, C.2
  • 53
    • 84926253921 scopus 로고    scopus 로고
    • Increased expression of Nodal correlates with reduced patient survival in pancreatic cancer
    • Kong B, Wang W, Esposito I, Friess H, Michalski CW, Kleeff J. Increased expression of Nodal correlates with reduced patient survival in pancreatic cancer. Pancreatology. 2015; 15:156-61.
    • (2015) Pancreatology , vol.15 , pp. 156-161
    • Kong, B.1    Wang, W.2    Esposito, I.3    Friess, H.4    Michalski, C.W.5    Kleeff, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.