Engineering of high yield production of L-serine in Escherichia coli

Biotechnology and Bioengineering

Volumn 113, Issue 4, 2016, Pages 807-816

  Mundhada, Hemanshu ^a   Schneider, Konstantin ^a   Christensen, Hanne Bjerre ^a   Nielsen, Alex Toftgaard ^a  

^a Chalmers University of Technology   (Denmark)

Author keywords

Amino acids; E. coli; Fermentation; L serine production; L serine toxicity; Metabolic engineering

Indexed keywords

ESCHERICHIA COLI; FERMENTATION; GLUCOSE; METABOLIC ENGINEERING;

BATCH FERMENTATION; E. COLI; FED-BATCH FERMENTATION; L-SERINE; LOW CONCENTRATIONS; POTENTIAL BUILDING BLOCKS; PRODUCTION PATHWAYS; RANDOM MUTAGENESIS;

AMINO ACIDS;

DEAMINASE; EAMA PROTEIN; GLYCINE; GLYCINE HYDROXYMETHYLTRANSFERASE; METHYLTRANSFERASE; NUCLEOTIDE TRANSPORTER; PYRUVIC ACID; SDAA PROTEIN; SDAB PROTEIN; SERA PROTEIN; SERB PROTEIN; SERC PROTEIN; SERINE; TDCG PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; ESCHERICHIA COLI; FED BATCH FERMENTATION; FEEDBACK SYSTEM; GENE DELETION; GENE MUTATION; GENE OVEREXPRESSION; GENE SEQUENCE; GROWTH RATE; METABOLIC ENGINEERING; MUTAGENESIS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; DRUG TOLERANCE; GENE EXPRESSION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PROCEDURES; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; DRUG TOLERANCE; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; MUTATION; SERINE;

EID: 84959482163     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25844     Document Type: Article

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