A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines

International Journal for Parasitology

Volumn 42, Issue 11, 2012, Pages 999-1006

  Delves, Michael J ^a   Ramakrishnan, Chandra ^a   Blagborough, Andrew M ^a   Leroy, Didier ^b   Wells, Timothy N C ^b   Sinden, Robert E ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Medicines for Malaria Venture   (Switzerland)

Author keywords

Drug; GFP; Malaria; Ookinete; Screening; Transmission; Vaccine

Indexed keywords

ANTIMALARIAL AGENT; ATOVAQUONE; CELL PROTEIN; CIRCUMSPOROZOITE TRAP RELATED PROTEIN; CYCLOHEXIMIDE; GREEN FLUORESCENT PROTEIN; MALARIA VACCINE; PYRONARIDINE; THIOSTREPTON; UNCLASSIFIED DRUG;

ACCURACY ASSESSMENT; BIOASSAY; DISEASE CONTROL; DISEASE TRANSMISSION; DOSE-RESPONSE RELATIONSHIP; IDENTIFICATION METHOD; MALARIA; MORBIDITY; MORTALITY;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DETERMINATION; DRUG EFFICACY; FEMALE; GROWTH INHIBITION; HIGH THROUGHPUT SCREENING; INFECTION CONTROL; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PROCESS DEVELOPMENT; PROTEIN EXPRESSION; REPRODUCIBILITY; VALIDATION PROCESS;

ANIMALS; ANTIMALARIALS; BIOLOGICAL ASSAY; FEMALE; GERM CELLS; INSECT VECTORS; LUMINESCENT MEASUREMENTS; MALARIA VACCINES; MICE; PARASITIC SENSITIVITY TESTS; PLASMODIUM BERGHEI; PLASMODIUM MALARIAE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

PLASMODIUM BERGHEI; RODENTIA;

EID: 84868102213     PISSN: 00207519     EISSN: 18790135     Source Type: Journal    
DOI: 10.1016/j.ijpara.2012.08.009     Document Type: Article

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