Nowhere to hide: Interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination

Malaria Journal

Volumn 14, Issue 1, 2015, Pages

  Reader, Janette ^a   Botha, Mariëtte ^a   Theron, Anjo ^b   Lauterbach, Sonja B ^c   Rossouw, Claire ^b   Engelbrecht, Dewaldt ^c   Wepener, Melanie ^c   Smit, Annél ^a   Leroy, Didier ^d   Mancama, Dalu ^b   Coetzer, Theresa L ^c   Birkholtz, Lyn Marie ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b DSI CSIR Nanotechnology Innovation Centre   (South Africa)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d Medicines for Malaria Venture   (Switzerland)

Author keywords

Gametocyte; Gametocytocidal compounds; Malaria; Plasmodium falciparum; Transmission blocking assays

Indexed keywords

ADENOSINE TRIPHOSPHATE; LACTATE DEHYDROGENASE; ANTIMALARIAL AGENT;

ACCURACY; ARTICLE; CONTROLLED STUDY; EVALUATION STUDY; GAMETOCYTE; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; LUCIFERASE ASSAY; MALARIA; METABOLIC PARAMETERS; NONHUMAN; PLASMODIUM FALCIPARUM; SCREENING; VALIDATION PROCESS; DISEASE ERADICATION; DRUG DEVELOPMENT; DRUG EFFECTS; DRUG SENSITIVITY; PROCEDURES;

ANTIMALARIALS; DISEASE ERADICATION; DRUG DISCOVERY; MALARIA; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM;

EID: 84931274354     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/s12936-015-0718-z     Document Type: Article

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