Targeting HO-1 by epigallocatechin-3-gallate reduces contrast-induced renal injury via anti-oxidative stress and anti-inflammation pathways

PLoS ONE

Volumn 11, Issue 2, 2016, Pages

  Gao, Zhao ^a,b   Han, Yu ^a,b   Hu, Yunhui ^a,b   Wu, Xiaoyan ^a,b   Wang, Yongbin ^a,b   Zhang, Xiaoqun ^a,b   Fu, Jinjuan ^a,b   Zou, Xue ^a,b   Zhang, Jun ^a,b   Chen, Xiongwen ^a,b   Jose, Pedro A ^c   Lu, Xi ^a,b   Zeng, Chunyu ^a,b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Chongqing Institute of Cardiology   (China)

^c GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CRYOPYRIN; EPIGALLOCATECHIN GALLATE; HEME OXYGENASE 1; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; PROTOPORPHYRIN; PROTOPORPHYRIN IX ZINC; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; CARRIER PROTEIN; CATECHIN; CONTRAST MEDIUM; HEME OXYGENASE; HMOX1 PROTEIN, RAT; INFLAMMASOME; NLRP3 PROTEIN, RAT; PROTOPORPHYRIN ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTRAST INDUCED NEPHROPATHY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; HISTOPATHOLOGY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; SIGNAL TRANSDUCTION; TUNEL ASSAY; UPREGULATION; UREA NITROGEN BLOOD LEVEL; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; FLUORESCENCE MICROSCOPY; INFLAMMATION; KIDNEY; KIDNEY DISEASES; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME FACTOR;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARRIER PROTEINS; CATECHIN; CONTRAST MEDIA; DOWN-REGULATION; HEME OXYGENASE (DECYCLIZING); IN SITU NICK-END LABELING; INFLAMMASOMES; INFLAMMATION; KIDNEY; KIDNEY DISEASES; MALE; MICROSCOPY, FLUORESCENCE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OXIDATIVE STRESS; PROTOPORPHYRINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION;

EID: 84959449660     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0149032     Document Type: Article

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