Therapeutic potential of EGCG on acute renal damage in a rat model of obstructive nephropathy

Molecular Medicine Reports

Volumn 7, Issue 4, 2013, Pages 1096-1102

  Zhou, Ping ^a,b   Yu, Jin Feng ^c   Zhao, Cheng Guang ^a   Sui, Feng Xuan ^c   Teng, Xu ^a   Wu, Yu Bin ^a,d  

^a CHINA MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c MUDANJIANG MEDICAL UNIVERSITY   (China)

^d Shengjing Hospital of China Medical University   (China)

Author keywords

GCS; ( ) epigallocatechin 3 O gallate; Nrf2; Obstructive nephropathy; Oxidative stress

Indexed keywords

EPIGALLOCATECHIN GALLATE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; KIDNEY PARENCHYMA; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RENAL PROTECTION; URETER LIGATION; URETER OBSTRUCTION; WESTERN BLOTTING;

ACUTE KIDNEY INJURY; ANIMALS; ANTIOXIDANTS; CATECHIN; DISEASE MODELS, ANIMAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMANS; INFUSIONS, PARENTERAL; KIDNEY; MALE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84875252886     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1296     Document Type: Article

References (21)

1. Klahr S: Obstructive Nephropathy. Internal Med 39: 355-361, 2000.
2. Robertson JL: Chemically induced glomerular injury. A review of basic mechanisms and specific xenobiotics. Toxicol Pathol 26: 64-72, 1998.
3. Zalba G, Fortuño A and Díez J: Oxidative stress and atherosclerosis in early chronic kidney disease. Nephrol Dial Transplant 21: 2686-2690, 2006.
4. Yang CS: Inhibition of carcinogenesis by tea. Nature 389: 134-135, 1997.
5. Fujiki H, Suganuma M, Okabe S, et al: Cancer inhibition by green tea. Mutat Res 402: 307-310, 1998.
6. Mukhtar H and Ahmad N: Mechanism of cancer chemopreventive activity of green tea. Proc Soc Exp Biol Med 220: 234-238, 1999.
7. Suganuma M, Okabe S, Sueoka N, et al: Green tea and cancer chemoprevention. Mutat Res 428: 339-344, 1999.
8. Robak J and Gryglewski RJ: Flavonoids are scavengers of superoxide anions. Biochem Pharmacol 37: 837-841, 1988.
9. Yang CS, Lambert JD, Hou Z, Ju J, Lu G and Hao X: Molecular targets for the cancer preventive activity of tea polyphenols. Mol Carcinog 45: 431-435, 2006.
10. Yang CS, Prabhu S and Landau J: Prevention of carcinogenesis by tea polyphenols. Drug Metabolism Reviews 33: 237-253, 2001.
11. Chen C, Yu R, Owuor ED and Kong AN: Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Arch Pharm Res 23: 605-612, 2000.
12. Cho HY, Jedlicka AE, Reddy SP, et al: Role of NRF2 in protection against hyperoxic lung injury in mice. Am J Respir Cell Mol Biol 26: 175-182, 2002.
13. Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M and Biswal S: Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res 62: 5196-5203, 2002.
14. Hu R, Xu C, Shen G, et al: Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray. Life Sci 79: 1944-1955, 2006.
15. Shelby MK and Klaassen CD: Induction of rat UDP-glucurono-syltransferases in liver and duodenum by microsomal enzyme inducers that activate various transcriptional pathways. Drug Metab Dispos 34: 1772-1778, 2006.
16. Wu CC, Hsu MC, Hsieh CW, Lin JB, Lai PH and Wung BS: Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways. Life Sci 78: 2889-2897, 2006.
17. Yang XY, Zhao WP, Li YQ, et al: The role of NF-E2-related factor 2 in the induction of uridine 5-diphosphate-glucuronosyltransferase 1A and its isoforms by epigallocatechin gallate in colon cancer cells. Zhonghua Yi Xue Za Zhi 86: 82-87, 2006.
18. Andreadi CK, Howells LM, Atherfold PA and Manson MM: Involvement of Nrf2, p38, BRaf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols. Mol Pharmacol 69: 1033-1040, 2006.
19. Dalton TP, Dieter MZ, Yang Y, Shertzer HG and Nebert DW: The most glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterzygous. Biochem Biophys Res Commun 20: 279, 2000.
20. Itoh K, Chiba T, Takahashi S, et al: An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236: 313-322, 1997.
21. Chan JY and Kwong M: Impaired expression of glutathione synthetic enzyme genes in mice with targeteddeletion of the Nrf2 basic-leucine zipper protein. Biochim Biophys Acta 1517: 19-26, 2000.