Hemin and a metabolic derivative coprohemin modulate the TLR4 pathway differently through different molecular targets

Innate Immunity

Volumn 17, Issue 3, 2011, Pages 293-301

  Piazza, Matteo ^a   Damore, Gaetana ^a   Costa, Barbara ^a   Gioannini, Theresa L ^b,c   Weiss, Jerrold P ^b   Peri, Francesco ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

coprohemin; heme; hemin; MD 2; TLR4

Indexed keywords

CD14 ANTIGEN; ENDOTOXIN; HEMIN; INTERLEUKIN 8; PROTEIN MD 2; TOLL LIKE RECEPTOR 4;

ARTICLE; BIOCHEMISTRY; CELL STRAIN HEK293; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; HUMAN; HUMAN CELL; OXIDATION; PROTEIN FUNCTION; PROTEIN INTERACTION;

ANTIGENS, CD14; ENDOTOXINS; HEK293 CELLS; HEMIN; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-8; LYMPHOCYTE ANTIGEN 96; OXIDATION-REDUCTION; PROTEIN BINDING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 77957288082     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425910369020     Document Type: Article

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