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Volumn 6, Issue , 2016, Pages

The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCIUM SENSING RECEPTOR; CHLORIDE CHANNEL; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EYE PROTEIN; ION CHANNEL; TMEM16A PROTEIN, MOUSE; VMD2 PROTEIN, MOUSE;

EID: 84959432853     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep21975     Document Type: Article
Times cited : (42)

References (67)
  • 1
    • 17844393409 scopus 로고    scopus 로고
    • Molecular mechanisms of early lung specification and branching morphogenesis
    • Warburton, D. et al. Molecular mechanisms of early lung specification and branching morphogenesis. Pediatr Res 57, 26R-37R, doi: 10.1203/01.PDR.0000159570.01327.ED (2005).
    • (2005) Pediatr Res , vol.57 , pp. 26R-37R
    • Warburton, D.1
  • 2
    • 0030038048 scopus 로고    scopus 로고
    • Regulation of lung expansion and lung growth before birth
    • Harding, R. & Hooper, S. B. Regulation of lung expansion and lung growth before birth. J Appl Physiol (1985) 81, 209-224 (1996).
    • (1996) J Appl Physiol (1985) , vol.81 , pp. 209-224
    • Harding, R.1    Hooper, S.B.2
  • 3
    • 77955358457 scopus 로고    scopus 로고
    • Lung organogenesis
    • Warburton, D. et al. Lung organogenesis. Curr Top Dev Biol 90, 73-158, doi: 10.1016/s0070-2153(10)90003-3 (2010).
    • (2010) Curr Top Dev Biol , vol.90 , pp. 73-158
    • Warburton, D.1
  • 4
    • 0028818707 scopus 로고
    • Lung fluid restriction affects growth but not airway branching of embryonic rat lung
    • Souza, P., Obrodovich, H. & Post, M. Lung Fluid Restriction Affects Growth but Not Airway Branching of Embryonic Rat Lung. Int J Dev Biol 39, 629-637 (1995).
    • (1995) Int J Dev Biol , vol.39 , pp. 629-637
    • Souza, P.1    Obrodovich, H.2    Post, M.3
  • 5
    • 5444221907 scopus 로고    scopus 로고
    • Genetic disorders influencing lung formation and function at birth
    • Whitsett, J. A., Wert, S. E. & Trapnell, B. C. Genetic disorders influencing lung formation and function at birth. Hum Mol Genet 13 Spec No 2, R207-215, doi: 10.1093/hmg/ddh252 (2004).
    • (2004) Hum Mol Genet , vol.13 , pp. R207-R215
    • Whitsett, J.A.1    Wert, S.E.2    Trapnell, B.C.3
  • 6
    • 0017656561 scopus 로고
    • Morphological effects of chronic tracheal ligation and drainage in the fetal lamb lung
    • Alcorn, D. et al. Morphological effects of chronic tracheal ligation and drainage in the fetal lamb lung. J Anat 123, 649-660 (1977).
    • (1977) J Anat , vol.123 , pp. 649-660
    • Alcorn, D.1
  • 7
    • 0016278196 scopus 로고
    • Ion fluxes across the pulmonary epithelium and the secretion of lung liquid in the foetal lamb
    • Olver, R. E. & Strang, L. B. Ion fluxes across the pulmonary epithelium and the secretion of lung liquid in the foetal lamb. J Physiol 241, 327-357 (1974).
    • (1974) J Physiol , vol.241 , pp. 327-357
    • Olver, R.E.1    Strang, L.B.2
  • 8
    • 0001322240 scopus 로고
    • Congenital diaphragmatic hernia as a cause of perinatal mortality
    • Butler, N. & Claireaux, A. E. Congenital diaphragmatic hernia as a cause of perinatal mortality. Lancet 1, 659-663 (1962).
    • (1962) Lancet , vol.1 , pp. 659-663
    • Butler, N.1    Claireaux, A.E.2
  • 9
    • 0020646190 scopus 로고
    • Upper airway dynamics during breathing and during apnoea in fetal lambs
    • Fewell, J. E. & Johnson, P. Upper airway dynamics during breathing and during apnoea in fetal lambs. J Physiol 339, 495-504 (1983).
    • (1983) J Physiol , vol.339 , pp. 495-504
    • Fewell, J.E.1    Johnson, P.2
  • 10
    • 57649188014 scopus 로고    scopus 로고
    • Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR
    • Finney, B. A. et al. Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. J Physiol 586, 6007-6019, doi: 10.1113/jphysiol.2008.161687 (2008).
    • (2008) J Physiol , vol.586 , pp. 6007-6019
    • Finney, B.A.1
  • 11
    • 0023946449 scopus 로고
    • Ion transport in cultured fetal and adult rabbit tracheal epithelia
    • Zeitlin, P. L., Loughlin, G. M. & Guggino, W. B. Ion transport in cultured fetal and adult rabbit tracheal epithelia. Am J Physiol 254, C691-698 (1988).
    • (1988) Am J Physiol , vol.254 , pp. C691-698
    • Zeitlin, P.L.1    Loughlin, G.M.2    Guggino, W.B.3
  • 12
    • 0025885003 scopus 로고
    • Developing fetal alveolar epithelial cells secrete fluid in primary culture
    • McCray, P. B. Jr. & Welsh, M. J. Developing fetal alveolar epithelial cells secrete fluid in primary culture. Am J Physiol 260, L494-500 (1991).
    • (1991) Am J Physiol , vol.260 , pp. L494-500
    • McCray, P.B.1    Welsh, M.J.2
  • 13
    • 0020957948 scopus 로고
    • Mode of chloride secretion by lung epithelia
    • Gatzy, J. T. Mode of chloride secretion by lung epithelia. Am Rev Respir Dis 127, S14-16 (1983).
    • (1983) Am Rev Respir Dis , vol.127 , pp. S14-16
    • Gatzy, J.T.1
  • 14
    • 2342517571 scopus 로고    scopus 로고
    • Developmental regulation of lung liquid transport
    • Olver, R. E., Walters, D. V. & S, M. W. Developmental regulation of lung liquid transport. Annu Rev Physiol 66, 77-101, doi: 10.1146/ annurev.physiol.66.071702.145229 (2004).
    • (2004) Annu Rev Physiol , vol.66 , pp. 77-101
    • Olver, R.E.1    Walters, D.V.2    Sm, W.3
  • 15
    • 0031471679 scopus 로고    scopus 로고
    • Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation
    • Kovacs, C. S. & Kronenberg, H. M. Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation. Endocr Rev 18, 832-872 (1997).
    • (1997) Endocr Rev , vol.18 , pp. 832-872
    • Kovacs, C.S.1    Kronenberg, H.M.2
  • 16
    • 79956190209 scopus 로고    scopus 로고
    • An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung
    • Finney, B. et al. An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung. Exp Lung Res 37, 269-278, doi: 10.3109/01902148.2010.545471 (2011).
    • (2011) Exp Lung Res , vol.37 , pp. 269-278
    • Finney, B.1
  • 17
    • 0027765508 scopus 로고
    • Cloning and characterization of an extracellular Ca(2+ )-sensing receptor from bovine parathyroid
    • Brown, E. M. et al. Cloning and characterization of an extracellular Ca(2+ )-sensing receptor from bovine parathyroid. Nature 366, 575-580, doi: 10.1038/366575a0 (1993).
    • (1993) Nature , vol.366 , pp. 575-580
    • Brown, E.M.1
  • 18
    • 84857296021 scopus 로고    scopus 로고
    • The calcium-sensing receptor beyond extracellular calcium homeostasis: Conception, development, adult physiology, and disease
    • Riccardi, D. & Kemp, P. J. The calcium-sensing receptor beyond extracellular calcium homeostasis: conception, development, adult physiology, and disease. Annu Rev Physiol 74, 271-297, doi: 10.1146/annurev-physiol-020911-153318 (2012).
    • (2012) Annu Rev Physiol , vol.74 , pp. 271-297
    • Riccardi, D.1    Kemp, P.J.2
  • 19
    • 1642459433 scopus 로고    scopus 로고
    • Inhibition of CLC-2 chloride channel expression interrupts expansion of fetal lung cysts
    • Blaisdell, C. J. et al. Inhibition of CLC-2 chloride channel expression interrupts expansion of fetal lung cysts. Am J Physiol Lung Cell Mol Physiol 286, L420-426, doi: 10.1152/ajplung.00113.2003 (2004).
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.286 , pp. L420-426
    • Blaisdell, C.J.1
  • 20
    • 0029316542 scopus 로고
    • CIC-2: A developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth
    • Murray, C. B. et al. CIC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth. Am J Respir Cell Mol Biol 12, 597-604, doi: 10.1165/ajrcmb.12.6.7766424 (1995).
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 597-604
    • Murray, C.B.1
  • 21
    • 51549098165 scopus 로고    scopus 로고
    • Expression of TMEM16 paralogs during murine embryogenesis
    • Rock, J. R. & Harfe, B. D. Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn 237, 2566-2574, doi: 10.1002/ dvdy.21676 (2008).
    • (2008) Dev Dyn , vol.237 , pp. 2566-2574
    • Rock, J.R.1    Harfe, B.D.2
  • 22
    • 49049118639 scopus 로고    scopus 로고
    • The transmembrane protein TMEM16A is required for normal development of the murine trachea
    • Rock, J. R., Futtner, C. R. & Harfe, B. D. The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol 321, 141-149, doi: 10.1016/j.ydbio.2008.06.009 (2008).
    • (2008) Dev Biol , vol.321 , pp. 141-149
    • Rock, J.R.1    Futtner, C.R.2    Harfe, B.D.3
  • 23
    • 50849126787 scopus 로고    scopus 로고
    • Bestrophin 1 and 2 are components of the Ca(2+ ) activated Cl(-) conductance in mouse airways
    • Clin Exp Immunol
    • Clin Exp Immunol Barro-Soria, R., Schreiber, R. & Kunzelmann, K. Bestrophin 1 and 2 are components of the Ca(2+ ) activated Cl(-) conductance in mouse airways. Biochim Biophys Acta 1783, 1993-2000, doi: 10.1016/j.bbamcr.2008.06.016 (2008).
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 1993-2000
    • Barro-Soria, R.1    Schreiber, R.2    Kunzelmann, K.3
  • 24
    • 0027755409 scopus 로고
    • Expression of CFTR and a cAMP-stimulated chloride secretory current in cultured human fetal alveolar epithelial cells
    • McCray, P. B., Jr., Bettencourt, J. D., Bastacky, J., Denning, G. M. & Welsh, M. J. Expression of CFTR and a cAMP-stimulated chloride secretory current in cultured human fetal alveolar epithelial cells. Am J Respir Cell Mol Biol 9, 578-585, doi: 10.1165/ajrcmb/9.6.578 (1993).
    • (1993) Am J Respir Cell Mol Biol , vol.9 , pp. 578-585
    • McCray, P.B.1    Bettencourt, J.D.2    Bastacky, J.3    Denning, G.M.4    Welsh, M.J.5
  • 25
    • 84959418002 scopus 로고
    • Department of Health, London, UK
    • Department of Health. (Department of Health, London, UK, 1995).
    • (1995)
    • Department of Health1
  • 27
    • 11144317908 scopus 로고    scopus 로고
    • Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung
    • De Langhe, S. P. et al. Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung. Dev Biol 277, 316-331, doi: 10.1016/j.ydbio.2004.09.023 (2005).
    • (2005) Dev Biol , vol.277 , pp. 316-331
    • De Langhe, S.P.1
  • 28
    • 30544449814 scopus 로고    scopus 로고
    • VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis
    • Del Moral, P. M. et al. VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis. Dev Biol 290, 177-188, doi: 10.1016/j.ydbio.2005.11.022 (2006).
    • (2006) Dev Biol , vol.290 , pp. 177-188
    • Del Moral, P.M.1
  • 29
    • 77952999989 scopus 로고    scopus 로고
    • Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation
    • Del Moral, P. M. & Warburton, D. Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation. Methods Mol Biol 633, 71-79, doi: 10.1007/978-1-59745-019-5-5 (2010).
    • (2010) Methods Mol Biol , vol.633 , pp. 71-79
    • Del Moral, P.M.1    Warburton, D.2
  • 30
    • 77951782126 scopus 로고    scopus 로고
    • Chloride channels: Often enigmatic, rarely predictable
    • Duran, C., Thompson, C. H., Xiao, Q. & Hartzell, H. C. Chloride channels: often enigmatic, rarely predictable. Annu Rev Physiol 72, 95-121, doi: 10.1146/annurev-physiol-021909-135811 (2010).
    • (2010) Annu Rev Physiol , vol.72 , pp. 95-121
    • Duran, C.1    Thompson, C.H.2    Xiao, Q.3    Hartzell, H.C.4
  • 31
    • 84930818625 scopus 로고    scopus 로고
    • Characterization of the effects of Cl(-) channel modulators on TMEM16A and bestrophin-1 Ca(2+ ) activated Cl (-) channels
    • Liu, Y. et al. Characterization of the effects of Cl(-) channel modulators on TMEM16A and bestrophin-1 Ca(2+ ) activated Cl (-) channels. Pflugers Arch 467, 1417-1430, doi: 10.1007/s00424-014-1572-5 (2015).
    • (2015) Pflugers Arch , vol.467 , pp. 1417-1430
    • Liu, Y.1
  • 32
    • 80052311732 scopus 로고    scopus 로고
    • High-throughput screening of libraries of compounds to identify CFTR modulators
    • Pedemonte, N., Zegarra-Moran, O. & Galietta, L. J. High-throughput screening of libraries of compounds to identify CFTR modulators. Methods Mol Biol 741, 13-21, doi: 10.1007/978-1-61779-117-8-2 (2011).
    • (2011) Methods Mol Biol , vol.741 , pp. 13-21
    • Pedemonte, N.1    Zegarra-Moran, O.2    Galietta, L.J.3
  • 33
    • 36248944146 scopus 로고    scopus 로고
    • Evolution of CFTR protein distribution in lung tissue from normal and CF human fetuses
    • Marcorelles, P., Montier, T., Gillet, D., Lagarde, N. & Ferec, C. Evolution of CFTR protein distribution in lung tissue from normal and CF human fetuses. Pediatr Pulmonol 42, 1032-1040, doi: 10.1002/ppul.20690 (2007).
    • (2007) Pediatr Pulmonol , vol.42 , pp. 1032-1040
    • Marcorelles, P.1    Montier, T.2    Gillet, D.3    Lagarde, N.4    Ferec, C.5
  • 34
    • 0025148246 scopus 로고
    • The effects of furosemide and bumetanide on lung liquid production by in vitro lungs from fetal Guinea pigs
    • Thom, J. & Perks, A. M. The effects of furosemide and bumetanide on lung liquid production by in vitro lungs from fetal guinea pigs. Can J Physiol Pharmacol 68, 1131-1135 (1990).
    • (1990) Can J Physiol Pharmacol , vol.68 , pp. 1131-1135
    • Thom, J.1    Perks, A.M.2
  • 35
    • 0034915850 scopus 로고    scopus 로고
    • Liquid and ion transport by fetal airway and lung epithelia of mice deficient in sodium-potassium-2-chloride transporter
    • Gillie, D. J., Pace, A. J., Coakley, R. J., Koller, B. H. & Barker, P. M. Liquid and ion transport by fetal airway and lung epithelia of mice deficient in sodium-potassium-2-chloride transporter. Am J Respir Cell Mol Biol 25, 14-20, doi: 10.1165/ajrcmb.25.1.4500 (2001).
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 14-20
    • Gillie, D.J.1    Pace, A.J.2    Coakley, R.J.3    Koller, B.H.4    Barker, P.M.5
  • 36
    • 0032584086 scopus 로고    scopus 로고
    • Calcimimetics with potent and selective activity on the parathyroid calcium receptor
    • Nemeth, E. F. et al. Calcimimetics with potent and selective activity on the parathyroid calcium receptor. Proc Natl Acad Sci USA 95, 4040-4045 (1998).
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4040-4045
    • Nemeth, E.F.1
  • 37
    • 0036896008 scopus 로고    scopus 로고
    • Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion
    • Ma, T. et al. Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest 110, 1651-1658, doi: 10.1172/JCI16112 (2002).
    • (2002) J Clin Invest , vol.110 , pp. 1651-1658
    • Ma, T.1
  • 38
    • 0020503814 scopus 로고
    • Forskolin: A labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory, and adenylate cyclase activating properties
    • de Souza, N. J., Dohadwalla, A. N. & Reden, J. Forskolin: a labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory, and adenylate cyclase activating properties. Med Res Rev 3, 201-219 (1983).
    • (1983) Med Res Rev , vol.3 , pp. 201-219
    • De Souza, N.J.1    Dohadwalla, A.N.2    Reden, J.3
  • 39
    • 77955113473 scopus 로고    scopus 로고
    • CFTR-adenylyl cyclase i association responsible for UTP activation of CFTR in well-differentiated primary human bronchial cell cultures
    • Namkung, W., Finkbeiner, W. E. & Verkman, A. S. CFTR-adenylyl cyclase I association responsible for UTP activation of CFTR in well-differentiated primary human bronchial cell cultures. Mol Biol Cell 21, 2639-2648, doi: 10.1091/mbc.E09-12-1004 (2010).
    • (2010) Mol Biol Cell , vol.21 , pp. 2639-2648
    • Namkung, W.1    Finkbeiner, W.E.2    Verkman, A.S.3
  • 40
    • 0025043660 scopus 로고
    • Role of lung fluid volume in growth and maturation of the fetal sheep lung
    • Moessinger, A. C., Harding, R., Adamson, T. M., Singh, M. & Kiu, G. T. Role of lung fluid volume in growth and maturation of the fetal sheep lung. J Clin Invest 86, 1270-1277, doi: 10.1172/JCI114834 (1990).
    • (1990) J Clin Invest , vol.86 , pp. 1270-1277
    • Moessinger, A.C.1    Harding, R.2    Adamson, T.M.3    Singh, M.4    Kiu, G.T.5
  • 41
    • 0001497722 scopus 로고
    • Fetal tracheal ligation and lung development
    • Carmel, J. A., Friedman, F. & Adams, F. H. Fetal Tracheal Ligation and Lung Development. Am J Dis Child 109, 452-456 (1965).
    • (1965) Am J Dis Child , vol.109 , pp. 452-456
    • Carmel, J.A.1    Friedman, F.2    Adams, F.H.3
  • 42
    • 0007184966 scopus 로고
    • Distensibility of fetal lung with fluid in sheep
    • Lanman, J. T., Schaffer, A., Castella.R., Ogawa, Y. & Herod, L. Distensibility of Fetal Lung with Fluid in Sheep. Pediatr Res 5, 586, doi: 10.1203/00006450-197111000-00002 (1971).
    • (1971) Pediatr Res , vol.5 , pp. 586
    • Lanman, J.T.1    Schaffer, A.2    Castella, R.3    Ogawa, Y.4    Herod, L.5
  • 43
    • 0026872650 scopus 로고
    • Secretion of lung fluid by the developing fetal rat alveolar epithelium in organ culture
    • McCray, P. B., Jr., Bettencourt, J. D. & Bastacky, J. Secretion of lung fluid by the developing fetal rat alveolar epithelium in organ culture. Am J Respir Cell Mol Biol 6, 609-616, doi: 10.1165/ajrcmb/6.6.609 (1992).
    • (1992) Am J Respir Cell Mol Biol , vol.6 , pp. 609-616
    • McCray, P.B.1    Bettencourt, J.D.2    Bastacky, J.3
  • 44
  • 45
    • 84886995603 scopus 로고    scopus 로고
    • Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle
    • Gallos, G. et al. Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 305, L625-634, doi: 10.1152/ajplung.00068.2013 (2013).
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.305 , pp. L625-634
    • Gallos, G.1
  • 46
    • 57749087873 scopus 로고    scopus 로고
    • Embryonic lung growth is normal in a CFTR-knockout mouse model
    • Wallace, H. L., Connell, M. G., Losty, P. D., Jesudason, E. C. & Southern, K. W. Embryonic lung growth is normal in a cftr-knockout mouse model. Exp Lung Res 34, 717-727, doi: 10.1080/01902140802389719 (2008).
    • (2008) Exp Lung Res , vol.34 , pp. 717-727
    • Wallace, H.L.1    Connell, M.G.2    Losty, P.D.3    Jesudason, E.C.4    Southern, K.W.5
  • 47
    • 27544434744 scopus 로고    scopus 로고
    • Developmental paradigm for early features of cystic fibrosis
    • Larson, J. E. & Cohen, J. C. Developmental paradigm for early features of cystic fibrosis. Pediatr Pulmonol 40, 371-377, doi: 10.1002/ ppul.20169 (2005).
    • (2005) Pediatr Pulmonol , vol.40 , pp. 371-377
    • Larson, J.E.1    Cohen, J.C.2
  • 48
    • 1542287428 scopus 로고    scopus 로고
    • Structural airway abnormalities in infants and young children with cystic fibrosis
    • Long, F. R., Williams, R. S. & Castile, R. G. Structural airway abnormalities in infants and young children with cystic fibrosis. J Pediatr 144, 154-161, doi: 10.1016/j.jpeds.2003.09.026 (2004).
    • (2004) J Pediatr , vol.144 , pp. 154-161
    • Long, F.R.1    Williams, R.S.2    Castile, R.G.3
  • 49
    • 0037081739 scopus 로고    scopus 로고
    • Temporal regulation of CFTR expression during ovine lung development: Implications for CF gene therapy
    • Broackes-Carter, F. C. et al. Temporal regulation of CFTR expression during ovine lung development: implications for CF gene therapy. Hum Mol Genet 11, 125-131 (2002).
    • (2002) Hum Mol Genet , vol.11 , pp. 125-131
    • Broackes-Carter, F.C.1
  • 50
    • 0027195534 scopus 로고
    • Cell-specific localization of CFTR mRNA shows developmentally regulated expression in human fetal tissues
    • Tizzano, E. F., Chitayat, D. & Buchwald, M. Cell-specific localization of CFTR mRNA shows developmentally regulated expression in human fetal tissues. Hum Mol Genet 2, 219-224 (1993).
    • (1993) Hum Mol Genet , vol.2 , pp. 219-224
    • Tizzano, E.F.1    Chitayat, D.2    Buchwald, M.3
  • 51
    • 0027966771 scopus 로고
    • Both CFTR and outwardly rectifying chloride channels contribute to cAMP-stimulated whole cell chloride currents
    • Schwiebert, E. M., Flotte, T., Cutting, G. R. & Guggino, W. B. Both CFTR and outwardly rectifying chloride channels contribute to cAMP-stimulated whole cell chloride currents. Am J Physiol 266, C1464-1477 (1994).
    • (1994) Am J Physiol , vol.266 , pp. C1464-1477
    • Schwiebert, E.M.1    Flotte, T.2    Cutting, G.R.3    Guggino, W.B.4
  • 52
    • 36048936399 scopus 로고    scopus 로고
    • Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR
    • Scott-Ward, T. S. et al. Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR. Proc Natl Acad Sci USA 104, 16365-16370, doi: 10.1073/pnas.0701562104 (2007).
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 16365-16370
    • Scott-Ward, T.S.1
  • 53
    • 0032522598 scopus 로고    scopus 로고
    • Comparison of the gating behaviour of human and murine cystic fibrosis transmembrane conductance regulator Cl- channels expressed in mammalian cells
    • Lansdell, K. A. et al. Comparison of the gating behaviour of human and murine cystic fibrosis transmembrane conductance regulator Cl- channels expressed in mammalian cells. J Physiol 508 (Pt 2), 379-392 (1998).
    • (1998) J Physiol , vol.508 , pp. 379-392
    • Lansdell, K.A.1
  • 54
    • 65949090315 scopus 로고    scopus 로고
    • Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor
    • Brennan, S. C. & Conigrave, A. D. Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor. Curr Pharm Biotechnol 10, 270-281 (2009).
    • (2009) Curr Pharm Biotechnol , vol.10 , pp. 270-281
    • Brennan, S.C.1    Conigrave, A.D.2
  • 55
    • 0032936619 scopus 로고    scopus 로고
    • Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis
    • Gadsby, D. C. & Nairn, A. C. Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis. Physiol Rev 79, S77-S107 (1999).
    • (1999) Physiol Rev , vol.79 , pp. S77-S107
    • Gadsby, D.C.1    Nairn, A.C.2
  • 56
    • 84918587329 scopus 로고    scopus 로고
    • Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion
    • Xie, R. et al. Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion. J Biol Chem 289, 34642-34653, doi: 10.1074/jbc.M114.592774 (2014).
    • (2014) J Biol Chem , vol.289 , pp. 34642-34653
    • Xie, R.1
  • 57
    • 0022462591 scopus 로고
    • Quantitative aspects of lung pathology in cystic fibrosis
    • Sobonya, R. E. & Taussig, L. M. Quantitative aspects of lung pathology in cystic fibrosis. Am Rev Respir Dis 134, 290-295 (1986).
    • (1986) Am Rev Respir Dis , vol.134 , pp. 290-295
    • Sobonya, R.E.1    Taussig, L.M.2
  • 58
    • 70249098142 scopus 로고    scopus 로고
    • Adult onset lung disease following transient disruption of fetal stretch-induced differentiation
    • Hudak, J. J., Killeen, E., Chandran, A., Cohen, J. C. & Larson, J. E. Adult onset lung disease following transient disruption of fetal stretch-induced differentiation. Respir Res 10, 34, doi: 10.1186/1465-9921-10-34 (2009).
    • (2009) Respir Res , vol.10 , pp. 34
    • Hudak, J.J.1    Killeen, E.2    Chandran, A.3    Cohen, J.C.4    Larson, J.E.5
  • 59
    • 15244355381 scopus 로고    scopus 로고
    • Pathophysiologic consequences following inhibition of a CFTR-dependent developmental cascade in the lung
    • Cohen, J. C. & Larson, J. E. Pathophysiologic consequences following inhibition of a CFTR-dependent developmental cascade in the lung. BMC Dev Biol 5, 2, doi: 10.1186/1471-213X-5-2 (2005).
    • (2005) BMC Dev Biol , vol.5 , pp. 2
    • Cohen, J.C.1    Larson, J.E.2
  • 60
    • 33749259836 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator (CFTR) dependent cytoskeletal tension during lung organogenesis
    • Cohen, J. C. & Larson, J. E. Cystic fibrosis transmembrane conductance regulator (CFTR) dependent cytoskeletal tension during lung organogenesis. Dev Dyn 235, 2736-2748, doi: 10.1002/dvdy.20912 (2006).
    • (2006) Dev Dyn , vol.235 , pp. 2736-2748
    • Cohen, J.C.1    Larson, J.E.2
  • 61
    • 77951978312 scopus 로고    scopus 로고
    • Mechanosensitive gating of CFTR
    • Zhang, W. K. et al. Mechanosensitive gating of CFTR. Nat Cell Biol 12, 507-512, doi: 10.1038/ncb2053 (2010).
    • (2010) Nat Cell Biol , vol.12 , pp. 507-512
    • Zhang, W.K.1
  • 62
    • 40649129499 scopus 로고    scopus 로고
    • A new missense mutation in the CASR gene in familial interstitial lung disease with hypocalciuric hypercalcemia and defective granulocyte function
    • Demedts, M. et al. A new missense mutation in the CASR gene in familial interstitial lung disease with hypocalciuric hypercalcemia and defective granulocyte function. Am J Respir Crit Care Med 177, 558-559, doi: 10.1164/ajrccm.177.5.558 (2008).
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 558-559
    • Demedts, M.1
  • 63
    • 6344254775 scopus 로고    scopus 로고
    • Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the aminoterminus of the human calcium receptor
    • Hu, J. et al. Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the aminoterminus of the human calcium receptor. J Bone Miner Res 19, 578-586, doi: 10.1359/JBMR.040106 (2004).
    • J Bone Miner Res , vol.19 , pp. 578-586
    • Hu, J.1
  • 64
    • 36048952655 scopus 로고    scopus 로고
    • Neonatal hyperparathyroidism and pamidronate therapy in an extremely premature infant
    • Fox, L. et al. Neonatal hyperparathyroidism and pamidronate therapy in an extremely premature infant. Pediatrics 120, e1350-1354, doi: 10.1542/peds.2006-3209 (2007).
    • (2007) Pediatrics , vol.120
    • Fox, L.1
  • 65
    • 0021921193 scopus 로고
    • Defective host defence mechanisms in a family with hypocalciuric hypercalcaemia and coexisting interstitial lung disease
    • Auwerx, J., Boogaerts, M., Ceuppens, J. L. & Demedts, M. Defective host defence mechanisms in a family with hypocalciuric hypercalcaemia and coexisting interstitial lung disease. Clinical and experimental immunology 62, 57-64 (1985).
    • (1985) Clinical and Experimental Immunology , vol.62 , pp. 57-64
    • Auwerx, J.1    Boogaerts, M.2    Ceuppens, J.L.3    Demedts, M.4
  • 66
    • 0022002945 scopus 로고
    • Coexistence of hypocalciuric hypercalcaemia and interstitial lung disease in a family: A cross-sectional study
    • Auwerx, J., Demedts, M., Bouillon, R. & Desmet, J. Coexistence of hypocalciuric hypercalcaemia and interstitial lung disease in a family: a cross-sectional study. European journal of clinical investigation 15, 6-14 (1985).
    • (1985) European Journal of Clinical Investigation , vol.15 , pp. 6-14
    • Auwerx, J.1    Demedts, M.2    Bouillon, R.3    Desmet, J.4
  • 67
    • 84555172118 scopus 로고    scopus 로고
    • A randomized controlled trial of fetal endoscopic tracheal occlusion versus postnatal management of severe isolated congenital diaphragmatic hernia
    • Ruano, R. et al. A randomized controlled trial of fetal endoscopic tracheal occlusion versus postnatal management of severe isolated congenital diaphragmatic hernia. Ultrasound Obstet Gynecol 39, 20-27, doi: 10.1002/uog.10142 (2012).
    • (2012) Ultrasound Obstet Gynecol , vol.39 , pp. 20-27
    • Ruano, R.1


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