Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung

Developmental Biology

Volumn 277, Issue 2, 2005, Pages 316-331

  De Langhe, Stijn P ^a   Sala, Frédéric G ^a   Del Moral, Pierre Marie ^a   Fairbanks, Timothy J ^a   Yamada, Kenneth M ^b   Warburton, David ^a   Burns, Robert C ^a   Bellusci, Saverio ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Branching morphogenesis; Dickkopf 1; Fibronectin; Lung; Smooth muscle; Vascular development; Wnt signaling

Indexed keywords

ALPHA ACTIN; FIBRONECTIN; INHIBITOR PROTEIN; PROTEIN; PROTEIN DICKKOPF 1; PROTEIN DICKKOPF 2; PROTEIN DICKKOPF 3; PROTEIN KREMEN1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; LUNG ALVEOLUS EPITHELIUM; LUNG BLOOD VESSEL; LUNG DEVELOPMENT; MOLECULAR DYNAMICS; MORPHOGENESIS; MOUSE; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TRANSCRIPTION INITIATION;

EID: 11144317908     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2004.09.023     Document Type: Article

References (52)

1. L. Alonso, and E. Fuchs Stem cells in the skin: waste not, Wnt not Genes Dev. 17 2003 1189 1200
2. T. Andl, S.T. Reddy, T. Gaddapara, and S.E. Millar WNT signals are required for the initiation of hair follicle development Dev. Cell 2 2002 643 653
3. W. Balemans, and W. Van Hul Extracellular regulation of BMP signaling in vertebrates: a cocktail of modulators Dev. Biol. 250 2002 231 250
4. E. Batlle, J.T. Henderson, H. Beghtel, M.M. van den Born, E. Sancho, G. Huls, J. Meeldijk, J. Robertson, M. van de Wetering, T. Pawson, and H. Clevers b-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB Cell 111 2002 251 263
5. S. Bellusci, R. Henderson, G. Winnier, T. Oikawa, and B.L. Hogan Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis Development 122 1996 1693 1702
6. S. Bellusci, J. Grindley, H. Emoto, N. Itoh, and B.L. Hogan Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung Development 124 1997 4867 4878
7. P.T. Chuang, T. Kawcak, and A.P. McMahon Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung Genes Dev 17 2003 342 347
8. R. DasGupta, and E. Fuchs Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation Development 126 1999 4557 4568
9. S.E. Gill, M.C. Pape, R. Khokha, A.J. Watson, and K.J. Leco A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis Dev. Biol. 261 2003 313 323
10. D. Gradl, M. Kuhl, and D. Wedlich The Wnt/Wg signal transducer beta-catenin controls fibronectin expression Mol. Cell Biol. 19 1999 5576 5587
11. C.P. Heisenberg, M. Tada, G.J. Rauch, L. Saude, M.L. Concha, R. Geisler, D.L. Stemple, J.C. Smith, and S.W. Wilson Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation Nature 405 2000 76 81
12. B.H. Hoang, T. Kubo, J.H. Healey, R. Yang, S.S. Nathan, E.A. Kolb, B. Mazza, P.A. Meyers, and R. Gorlick Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway Cancer Res. 64 2004 2734 2739
13. D.C. Hocking Fibronectin matrix deposition and cell contractility: implications for airway remodeling in asthma Chest 122 2002 275S 278S
14. B.L. Hogan Morphogenesis Cell 96 1999 225 233
15. B. Hogan, R. Beddington, F. Constantini, and E. Lacy Manipulating the Mouse Embryo 1994 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
16. I. Hokuto, A.K. Perl, and J.A. Whitsett Prenatal, but not postnatal, inhibition of fibroblast growth factor receptor signaling causes emphysema J. Biol. Chem. 278 2003 415 421
17. J. Huelsken, R. Vogel, B. Erdmann, G. Cotsarelis, and W. Birchmeier beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin Cell 105 2001 533 545
18. T. Ishitani, S. Kishida, J. Hyodo-Miura, N. Ueno, J. Yasuda, M. Waterman, H. Shibuya, R.T. Moon, J. Ninomiya-Tsuji, and K. Matsumoto The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling Mol. Cell Biol. 23 2003 131 139
19. Y. Kawano, and R. Kypta Secreted antagonists of the Wnt signalling pathway J. Cell Sci. 116 2003 2627 2634
20. S. Kim, K. Bell, S.A. Mousa, and J.A. Varner Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin Am. J. Pathol. 156 2000 1345 1362
21. S. Kim, M. Harris, and J.A. Varner Regulation of integrin alpha vbeta 3-mediated endothelial cell migration and angiogenesis by integrin alpha5beta1 and protein kinase A J. Biol. Chem. 275 2000 33920 33928
22. S. Kim, M. Bakre, H. Yin, and J.A. Varner Inhibition of endothelial cell survival and angiogenesis by protein kinase A J. Clin. Invest. 110 2002 933 941
23. 2+ signaling Mech. Dev. 106 2001 61 76
24. F. Kuhnert, C.R. Davis, H.T. Wang, P. Chu, M. Lee, J. Yuan, R. Nusse, and C.J. Kuo Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1 Proc. Natl. Acad. Sci. U. S. A. 101 2004 266 271
25. D. Lebeche, S. Malpel, and W.V. Cardoso Fibroblast growth factor interactions in the developing lung Mech. Dev. 86 1999 125 136
26. C. Li, J. Xiao, K. Hormi, Z. Borok, and P. Minoo Wnt5a participates in distal lung morphogenesis Dev. Biol. 248 2002 68 81
27. P. Lindahl, L. Karlsson, M. Hellstrom, S. Gebre-Medhin, K. Willetts, J.K. Heath, and C. Betsholtz Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development Development 124 1997 3943 3953
28. B. Mao, and C. Niehrs Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling Gene 302 2003 179 183
29. B. Mao, W. Wu, G. Davidson, J. Marhold, M. Li, B.M. Mechler, H. Delius, D. Hoppe, P. Stannek, C. Walter, A. Glinka, and C. Niehrs Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling Nature 417 2002 664 667
30. S. Maretto, M. Cordenonsi, S. Dupont, P. Braghetta, V. Broccoli, A.B. Hassan, D. Volpin, G.M. Bressan, and S. Piccolo Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors Proc. Natl. Acad. Sci. U. S. A. 100 2003 3299 3304
31. B.J. Merrill, U. Gat, R. DasGupta, and E. Fuchs Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin Genes Dev. 15 2001 1688 1705
32. S.J. Monkley, S.J. Delaney, D.J. Pennisi, J.H. Christiansen, and B.J. Wainwright Targeted disruption of the Wnt2 gene results in placentation defects Development 122 1996 3343 3353
33. M.L. Mucenski, S.E. Wert, J.M. Nation, D.E. Loudy, J. Huelsken, W. Birchmeier, E.E. Morrisey, and J.A. Whitsett beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis J. Biol. Chem. 278 2003 40231 40238
34. M. Mukhopadhyay, S. Shtrom, C. Rodriguez-Esteban, L. Chen, T. Tsukui, L. Gomer, D.W. Dorward, A. Glinka, A. Grinberg, S.P. Huang, C. Niehrs, J.C. Belmonte, and H. Westphal Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse Dev. Cell 1 2001 423 434
35. T. Okubo, and B.L. Hogan Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm J. Biol. 3 2004 11
36. K.I. Pinson, J. Brennan, S. Monkley, B.J. Avery, and W.C. Skarnes An LDL-receptor-related protein mediates Wnt signalling in mice Nature 407 2000 535 538
37. D. Pinto, A. Gregorieff, H. Begthel, and H. Clevers Canonical Wnt signals are essential for homeostasis of the intestinal epithelium Genes Dev. 17 2003 1709 1713
38. T. Reya, A.W. Duncan, L. Ailles, J. Domen, D.C. Scherer, K. Willert, L. Hintz, R. Nusse, and I.L. Weissman A role for Wnt signalling in self-renewal of haematopoietic stem cells Nature 423 2003 409 414
39. T. Sakai, M. Larsen, and K.M. Yamada Fibronectin requirement in branching morphogenesis Nature 423 2003 876 881
40. E.S. Seto, and H.J. Bellen The ins and outs of Wingless signaling Trends Cell Biol. 14 2004 45 53
41. F. Shalaby, J. Rossant, T.P. Yamaguchi, M. Gertsenstein, X.F. Wu, M.L. Breitman, and A.C. Schuh Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice Nature 376 1995 62 66
42. W. Shu, Y.Q. Jiang, M.M. Lu, and E.E. Morrisey Wnt7b regulates mesenchymal proliferation and vascular development in the lung Development 129 2002 4831 4842
43. K. Tamai, M. Semenov, Y. Kato, R. Spokony, C. Liu, Y. Katsuyama, F. Hess, J.P. Saint-Jeannet, and X. He LDL-receptor-related proteins in Wnt signal transduction Nature 407 2000 530 535
44. M. Tebar, O. Destree, W.J. de Vree, and A.A. Ten Have-Opbroek Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung Mech. Dev. 109 2001 437 440
45. V.J. Thannickal, D.Y. Lee, E.S. White, Z. Cui, J.M. Larios, R. Chacon, J.C. Horowitz, R.M. Day, and P.E. Thomas Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase J. Biol. Chem. 278 2003 12384 12389
46. L. Topol, X. Jiang, H. Choi, L. Garrett-Beal, P.J. Carolan, and Y. Yang Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation J. Cell Biol. 162 2003 899 908
47. M.A. Torres, J.A. Yang-Snyder, S.M. Purcell, A.A. DeMarais, L.L. McGrew, and R.T. Moon Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development J. Cell Biol. 133 1996 1123 1137
48. M. Wehrli, S.T. Dougan, K. Caldwell, L. O'Keefe, S. Schwartz, D. Vaizel-Ohayon, E. Schejter, A. Tomlinson, and S. DiNardo Arrow encodes an LDL-receptor-related protein essential for Wingless signalling Nature 407 2000 527 530
49. T.A. Westfall, R. Brimeyer, J. Twedt, J. Gladon, A. Olberding, M. Furutani-Seiki, and D.C. Slusarski Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity J. Cell Biol. 162 2003 889 898
50. G. Winnier, M. Blessing, P.A. Labosky, and B.L. Hogan Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse Genes Dev. 9 1995 2105 2116
51. Y. Yang, K.C. Palmer, N. Relan, C. Diglio, and L. Schuger Role of laminin polymerization at the epithelial mesenchymal interface in bronchial myogenesis Development 125 1998 2621 2629
52. J. Zhao, M. Lee, S. Smith, and D. Warburton Abrogation of Smad3 and Smad2 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture Dev. Biol. 194 1998 182 195