Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State

Cell Systems

Volumn 2, Issue 3, 2016, Pages 159-171

  Sacco, Francesca ^a,b   Silvestri, Alessandra ^a   Posca, Daniela ^a   Pirrò, Stefano ^a   Gherardini, Pier Federico ^a   Castagnoli, Luisa ^a   Mann, Matthias ^b   Cesareni, Gianni ^a,c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

METFORMIN; PHOSPHOPROTEOME; PROTEOME; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DRUG MECHANISM; GROWTH CURVE; GROWTH STIMULATION; HUMAN; IN VIVO STUDY; MASS SPECTROMETRY; MCF 7 CELL LINE; PRIORITY JOURNAL; PROTEOMICS; SIGNAL TRANSDUCTION; BREAST TUMOR; NON INSULIN DEPENDENT DIABETES MELLITUS;

BREAST NEOPLASMS; DIABETES MELLITUS, TYPE 2; HUMANS; HYPOGLYCEMIC AGENTS; METFORMIN; PROTEOMICS;

EID: 84959286939     PISSN: 24054712     EISSN: 24054720     Source Type: Journal    
DOI: 10.1016/j.cels.2016.02.005     Document Type: Article

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