Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

Nature Medicine

Volumn 22, Issue 4, 2016, Pages 397-403

  Song, Sung Won ^a,b   Miranda, Carlos J ^a   Braun, Lyndsey ^a   Meyer, Kathrin ^a   Frakes, Ashley E ^a,b   Ferraiuolo, Laura ^a   Likhite, Shibi ^a,b   Bevan, Adam K ^a,b   Foust, Kevin D ^a,b   McConnell, Michael J ^c   Walker, Christopher M ^b,d   Kaspar, Brian K ^a,b  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; HLA F ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DL2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; HLA ANTIGEN CLASS 1; HLA-F ANTIGENS; KIR3DL2 PROTEIN, HUMAN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DISEASE PREDISPOSITION; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOTONEURON; MOTOR PERFORMANCE; MOUSE; MOUSE MODEL; NERVE FIBER; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; AGED; ANIMAL; BIOSYNTHESIS; CADAVER; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; TRANSGENIC MOUSE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; CADAVER; CELL DEATH; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; MOTOR NEURONS; MUTATION; RECEPTORS, KIR3DL2; SUPEROXIDE DISMUTASE;

EID: 84959200193     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4052     Document Type: Article

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