Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome

BMC Genomics

Volumn 17, Issue 1, 2016, Pages

  Xu, Baoshan ^a   Gogol, Madelaine ^a   Gaudenz, Karin ^a   Gerton, Jennifer L ^a,b  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Cohesin; Gene expression; MTORC1 pathway; Ribosome profiling; Roberts syndrome (RBS); Translation

Indexed keywords

ACYLTRANSFERASE; COHESIN ACETYLTRANSFERASE; INITIATION FACTOR; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MICRORNA; RNA H19; SMALL NUCLEOLAR RNA; UNCLASSIFIED DRUG; ESCO2 PROTEIN, HUMAN; MTOR PROTEIN, HUMAN; NONHISTONE PROTEIN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ESCO2 GENE; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOCUS; GENOME IMPRINTING; GTL2 GENE; H19 GENE; HOX GENE; HUMAN; HUMAN CELL; RIBOSOME SUBUNIT; RNA SYNTHESIS; ROBERTS SYNDROME; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; TRANSLATION REGULATION; ANIMAL; BIOSYNTHESIS; CRANIOFACIAL MALFORMATION; DISEASE MODEL; GENETIC TRANSCRIPTION; GENETICS; HYPERTELORISM; METABOLISM; MUTATION; PHOCOMELIA; PROTEIN SYNTHESIS; RIBOSOME; ZEBRA FISH;

ACETYLTRANSFERASES; ANIMALS; CHROMOSOMAL PROTEINS, NON-HISTONE; CRANIOFACIAL ABNORMALITIES; DISEASE MODELS, ANIMAL; ECTROMELIA; HUMANS; HYPERTELORISM; LEUCINE; MUTATION; PROTEIN BIOSYNTHESIS; RIBOSOMES; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; ZEBRAFISH;

EID: 84959158239     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-2354-y     Document Type: Article

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