Cohesion promotes nucleolar structure and function

Molecular Biology of the Cell

Volumn 25, Issue 3, 2014, Pages 337-346

  Harris, Bethany ^a   Bose, Tania ^a   Lee, Kenneth K ^a   Wang, Fei ^a   Lu, Shuai ^a,b   Ross, Rhonda Trimble ^a   Zhang, Ying ^a   French, Sarah L ^c   Beyer, Ann L ^c   Slaughter, Brian D ^a   Unruh, Jay R ^a   Gerton, Jennifer L ^a,b  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COHESIN; DNA DIRECTED RNA POLYMERASE; RIBOSOME DNA; RIBOSOME RNA;

ARTICLE; BIOGENESIS; CELL ADHESION; CELL CYCLE; CELL FRACTIONATION; CELL FUNCTION; CELL MUTANT; CELL STRUCTURE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CROSS LINKING; CYTOMETRY; ELECTRON MICROSCOPY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENE MUTATION; NONHUMAN; NUCLEOLUS; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RIBOSOME; RNA CLEAVAGE; ROBERTS SYNDROME; STOICHIOMETRY; TRANSMISSION ELECTRON MICROSCOPY;

ACETYLTRANSFERASES; CELL CYCLE; CELL CYCLE PROTEINS; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; CRANIOFACIAL ABNORMALITIES; DNA, RIBOSOMAL; ECTROMELIA; HYPERTELORISM; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; NUCLEAR PROTEINS; NUCLEOLUS ORGANIZER REGION; RNA POLYMERASE I; RNA, RIBOSOMAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84893459333     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E13-07-0377     Document Type: Article

References (40)

1. Albert B, Leger-Silvestre I, Normand C, Ostermaier MK, Perez-Fernandez J, Panov KI, Zomerdijk JC, Schultz P, Gadal O (2011). RNA polymerase I-specific subunits promote polymerase clustering to enhance the rRNA gene transcription cycle. J Cell Biol 192, 277-293.
2. Beckouet F, Labarre-Mariotte S, Albert B, Imazawa Y, Werner M, Gada O, Nogi Y, Thuriaux P (2008). Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription. Mol Cell Biol 28, 1596-1605.
3. Bose T et al. (2012). Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells. PLoS Genet 8, e1002749.
4. Bose T, Gerton JL (2010). Cohesinopathies, gene expression, and chromatin organization. J Cell Biol 189, 201-210.
5. Deardorff MA et al. (2007). Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation. Am J Hum Genet 80, 485-494.
6. Deardorff MA et al. (2012a). HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature 489, 313-317.
7. Deardorff MA et al. (2012b). RAD21 mutations cause a human cohesinopathy. Am J Hum Genet 90, 1014-1027.
8. Fedoriw AM, Starmer J, Yee D, Magnuson T (2012). Nucleolar association and transcriptional inhibition through 5S rDNA in mammals. PLoS Genet 8, e1002468.
9. French SL, Osheim YN, Cioci F, Nomura M, Beyer AL (2003). In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol Cell Biol 23, 1558-1568.
10. Gard S, Light W, Xiong B, Bose T, McNairn AJ, Harris B, Fleharty B, Seidel C, Brickner JH, Gerton JL (2009). Cohesinopathy mutations disrupt the subnuclear organization of chromatin. J Cell Biol 187, 455-462.
11. Ghosh S et al. (2012). Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization. Mol Biol Cell 23, 2546-2559.
12. Guacci V, Koshland D, Strunnikov A (1997). A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. Cell 91, 47-57.
13. Heidinger-Pauli JM, Mert O, Davenport C, Guacci V, Koshland D (2010). Systematic reduction of cohesin differentially affects chromosome segregation, condensation, and DNA repair. Curr Biol 20, 957-963.
14. Hurt E, Hannus S, Schmelzl B, Lau D, Tollervey D, Simos G (1999). A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants. J Cell Biol 144, 389-401.
15. Kirkland JG, Kamakaka RT (2013). Long-range heterochromatin association is mediated by silencing and double-strand DNA break repair proteins. J Cell Biol 201, 809-826.
16. Kon A et al. (2013). Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms. Nat Genet 45, 1232-1237.
17. Kos M, Tollervey D (2010). Yeast pre-rRNA processing and modification occur cotranscriptionally. Mol Cell 37, 809-820.
18. Krantz ID et al. (2004). Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B. Nat Genet 36, 631-635.
19. Laferte A, Favry E, Sentenac A, Riva M, Carles C, Chedin S (2006). The transcriptional activity of RNA polymerase I is a key determinant for the level of all ribosome components. Genes Dev 20, 2030-2040.
20. Laloraya S, Guacci V, Koshland D (2000). Chromosomal addresses of the cohesin component Mcd1p. J Cell Biol 151, 1047-1056.
21. Ley TJ et al. (2013). Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 368, 2059-2074.
22. Li Z, Lee I, Moradi E, Hung NJ, Johnson AW, Marcotte EM (2009). Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7, e1000213.
23. Liu J, Krantz ID (2008). Cohesin and human disease. Annu Rev Genomics Hum Genet 9, 303-320.
24. Lu S, Goering M, Gard S, Xiong B, McNairn AJ, Jaspersen SL, Gerton JL (2010). Eco1 is important for DNA damage repair in S. cerevisiae. Cell Cycle 9, 3315-3327.
25. Mayan M, Aragon L (2010). Cis-interactions between non-coding ribosomal spacers dependent on RNAP-II separate RNAP-I and RNAP-III transcription domains. Cell Cycle 9, 4328-4337.
26. Narla A, Ebert BL (2010). Ribosomopathies: human disorders of ribosome dysfunction. Blood 115, 3196-3205.
27. Nemeth A et al. (2010). Initial genomics of the human nucleolus. PLoS Genet 6, e1000889.
28. Nemeth A, Langst G (2011). Genome organization in and around the nucleolus. Trends Genet 27, 149-156.
29. Osheim YN, French SL, Keck KM, Champion EA, Spasov K, Dragon F, Baserga SJ, Beyer AL (2004). Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae. Mol Cell 16, 943-954.
30. Rolef Ben-Shahar T, Heeger S, Lehane C, East P, Flynn H, Skehel M, Uhlmann F (2008). Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321, 563-566.
31. Rougemaille M et al. (2008). THO/Sub2p functions to coordinate 3'-end processing with gene-nuclear pore association. Cell 135, 308-321.
32. Schaaf CA, Kwak H, Koenig A, Misulovin Z, Gohara DW, Watson A, Zhou Y, Lis JT, Dorsett D (2013). Genome-wide control of RNA polymerase II activity by cohesin. PLoS Genet 9, e1003382.
33. Schneider DA, Michel A, Sikes ML, Vu L, Dodd JA, Salgia S, Osheim YN, Beyer AL, Nomura M (2007). Transcription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly. Mol Cell 26, 217-229.
34. Tan RZ, van Oudenaarden A (2010). Transcript counting in single cells reveals dynamics of rDNA transcription. Mol Syst Biol 6, 358.
35. Tonkin ET, Wang TJ, Lisgo S, Bamshad MJ, Strachan T (2004). NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome. Nat Genet 36, 636-641.
36. Unal E, Heidinger-Pauli JM, Kim W, Guacci V, Onn I, Gygi SP, Koshland DE (2008). A molecular determinant for the establishment of sister chromatid cohesion. Science 321, 566-569.
37. van Koningsbruggen S, Gierlinski M, Schofield P, Martin D, Barton GJ, Ariyurek Y, den Dunnen JT, Lamond AI (2010). High-resolution whole-genome sequencing reveals that specific chromatin domains from most human chromosomes associate with nucleoli. Mol Biol Cell 21, 3735-3748.
38. Vega H et al. (2005). Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion. Nat Genet 37, 468-470.
39. Xu B, Lee KK, Zhang L, Gerton JL (2013). Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet 9, e1003857.
40. Zhang Y, Wen Z, Washburn M P, Florens L (2010). Refinements to label free proteome quantitation: how to deal with peptides shared by multiple proteins. Anal Chem 82, 2272-2281.