L-leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway

Blood

Volumn 120, Issue 11, 2012, Pages 2214-2224

  Payne, Elspeth M ^a,b   Virgilio, Maria ^a   Narla, Anupama ^a   Sun, Hong ^a   Levine, Michelle ^a   Paw, Barry H ^a   Berliner, Nancy ^a   Look, A Thomas ^a   Ebert, Benjamin L ^a   Khanna Gupta, Arati ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; DEXTRO AMINO ACID; DEXTRO LEUCINE; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; RAPAMYCIN; SHORT HAIRPIN RNA; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLACKFAN DIAMOND ANEMIA; CHROMOSOME 5Q; CHROMOSOME DELETION 5; CHROMOSOME DELETION 5Q; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DRUG ACTIVITY; DRUG ANTAGONISM; EMBRYO; GENE; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; MYELODYSPLASTIC SYNDROME; NONHUMAN; PRIORITY JOURNAL; RPS14 GENE; RPS19 GENE; ZEBRA FISH;

EID: 84866315615     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-10-382986     Document Type: Article

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