Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence

Cell Reports

Volumn 14, Issue 7, 2016, Pages 1571-1580

  Spadaro, Olga ^a   Goldberg, Emily L ^a   Camell, Christina D ^a   Youm, Yun Hee ^a   Kopchick, John J ^b   Nguyen, Kim Y ^a   Bartke, Andrzej ^c   Sun, Liou Y ^d   Dixit, Vishwa Deep ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OHIO UNIVERSITY   (United States)

^c SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; GAMMA INTERFERON; GROWTH HORMONE RECEPTOR; INFLAMMASOME; SOMATOMEDIN C RECEPTOR; CARRIER PROTEIN; NLRP3 PROTEIN, MOUSE;

ADULT; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; EFFECTOR CELL; ENZYME ACTIVATION; GENE DELETION; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MIDDLE AGED; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SENESCENCE; T LYMPHOCYTE; YOUNG ADULT; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; CYTOLOGY; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; INNATE IMMUNITY; KNOCKOUT MOUSE; LONGEVITY; SIGNAL TRANSDUCTION; SPLEEN;

AGING; ANIMALS; AUTOCRINE COMMUNICATION; BONE MARROW CELLS; CARRIER PROTEINS; GENE EXPRESSION REGULATION; HOMEOSTASIS; IMMUNITY, INNATE; IMMUNOLOGIC MEMORY; INFLAMMASOMES; INTERFERON-GAMMA; LONGEVITY; MACROPHAGES; MICE; MICE, KNOCKOUT; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RECEPTOR, IGF TYPE 1; RECEPTORS, SOMATOTROPIN; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTES;

EID: 84959088069     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.01.044     Document Type: Article

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