Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome

Science

Volumn 351, Issue 6275, 2016, Pages

  Shi, Yuan ^a   Chen, Xiang ^b   Elsasser, Suzanne ^a   Stocks, Bradley B ^c   Tian, Geng ^a   Lee, Byung Hoon ^a   Shi, Yanhong ^b,d   Zhang, Naixia ^d   De Poot, Stefanie A H ^a   Tuebing, Fabian ^a   Sun, Shuangwu ^a   Vannoy, Jacob ^b,e   Tarasov, Sergey G ^b   Engen, John R ^c   Finley, Daniel ^a   Walters, Kylie J ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NORTHEASTERN UNIVERSITY   (United States)

^d SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^e Linganore High School   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUBIQUITINASE; LYSINE; PROTEASOME; PROTEIN; RAD23 PROTEIN; RPN1 PROTEIN; UBIQUITIN; UBP6 PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; PROTEINASE; RAD23 PROTEIN, S CEREVISIAE; RPN1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; UBP6 PROTEIN, S CEREVISIAE;

ENZYME; LIGAND; PROTEIN; SUBSTRATE; YEAST;

ARTICLE; CONTROLLED STUDY; GENE MUTATION; MOLECULAR RECOGNITION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; RECEPTOR BINDING; UBIQUITINATION; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR MODEL; MUTATION; SACCHAROMYCES CEREVISIAE;

DNA-BINDING PROTEINS; ENDOPEPTIDASES; METABOLIC NETWORKS AND PATHWAYS; MODELS, MOLECULAR; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN-SPECIFIC PROTEASES; UBIQUITINATION;

EID: 84959019581     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad9421     Document Type: Article

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