Hajdu cheney mouse mutants exhibit osteopenia, increased osteoclastogenesis, and bone resorption

Journal of Biological Chemistry

Volumn 291, Issue 4, 2016, Pages 1538-1551

  Canalis, Ernesto ^a   Schilling, Lauren ^a   Yee, Siu Pok ^a   Lee, Sun Kyeong ^a   Zanotti, Stefano ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALS;

GAIN-OF FUNCTION; NUCLEAR FACTOR KAPPAB; OSTEOBLAST DIFFERENTIATION; OSTEOCLAST CELLS; OSTEOCLAST DIFFERENTIATION; OSTEOCLASTOGENESIS; RECEPTOR ACTIVATOR; SKELETAL DEVELOPMENT;

BONE;

SEMAGACESTAT; NOTCH2 PROTEIN, MOUSE; NOTCH2 RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MASS; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENE MUTATION; HAJDU CHENEY SYNDROME; HETEROZYGOSITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MORPHOMETRICS; MOUSE; MOUSE MODEL; MOUSE MUTANT; NONHUMAN; NOTCH2 GENE; OSSIFICATION; OSTEOBLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; OSTEOPENIA; PRIORITY JOURNAL; RECEPTOR GENE; SEX DIFFERENCE; TRABECULAR BONE; ANIMAL; BONE DEVELOPMENT; CYTOLOGY; DISEASE MODEL; FEMUR; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLIC BONE DISEASE; METABOLISM; MISSENSE MUTATION; OSTEOCLAST; PATHOPHYSIOLOGY; POINT MUTATION;

ANIMALS; BONE DISEASES, METABOLIC; BONE RESORPTION; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; FEMALE; FEMUR; HAJDU-CHENEY SYNDROME; HUMANS; MALE; MICE; MUTATION, MISSENSE; OSTEOCLASTS; OSTEOGENESIS; POINT MUTATION; RECEPTOR, NOTCH2;

EID: 84959018830     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.685453     Document Type: Article

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