Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2

Journal of Biological Chemistry

Volumn 287, Issue 42, 2012, Pages 34904-34916

  Yuan, Zhenyu ^a   Friedmann, David R ^b   VanderWielen, Bradley D ^a   Collins, Kelly J ^a   Kovall, Rhett A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINES; CELL TYPES; COACTIVATORS; COMPLEX ASSEMBLY; DIFFERENT DOMAINS; DNA-BINDING PROTEIN; EMBRYONIC DEVELOPMENT; EMBRYONIC FIBROBLASTS; FUNCTIONAL ASSAYS; HUMAN DISEASE; IN-VIVO; INTRACELLULAR DOMAIN; MOLECULAR INSIGHTS; NOTCH RECEPTOR; RECEPTOR-LIGAND INTERACTIONS; SIGNALING PATHWAYS; TARGET GENES; TERNARY COMPLEX; TRANSCRIPTIONAL ACTIVATORS; TRANSCRIPTIONALLY ACTIVE; WILD TYPES;

CELL CULTURE; CHEMICAL ACTIVATION; GENES; TISSUE;

TRANSCRIPTION;

CBF1 SU(H) LAG1 PROTEIN; DNA BINDING PROTEIN; MUTANT PROTEIN; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONNECTIVE TISSUE CELL; CONTROLLED STUDY; EMBRYO; EMBRYONIC FIBROBLAST; GENE MUTATION; GENE TARGETING; GENETIC TRANSDUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE; RETROVIRUS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WILD TYPE;

ANIMALS; DNA-BINDING PROTEINS; HUMANS; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; MICE; MICE, KNOCKOUT; MUTATION; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84867415859     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.403287     Document Type: Article

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