Physiological notch signaling maintains bone homeostasis via RBPjk and hey upstream of NFATc1

PLoS Genetics

Volumn 8, Issue 3, 2012, Pages

  Tu, Xiaolin ^a,c   Chen, Jianquan ^a   Lim, Joohyun ^a   Karner, Courtney M ^a   Lee, Seung Yon ^a   Heisig, Julia ^b   Wiese, Cornelia ^b   Surendran, Kameswaran ^a   Kopan, Raphael ^a   Gessler, Manfred ^b   Long, Fanxin ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HEY1; TRANSCRIPTION FACTOR HEYL; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC1; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HAIRY, HRT1 PROTEIN; HEYL PROTEIN, MOUSE; NFATC1 PROTEIN, MOUSE; NOTCH1 PROTEIN, MOUSE; NOTCH2 PROTEIN, MOUSE; RBPJ PROTEIN, MOUSE; REPRESSOR PROTEIN;

ARTICLE; BONE HOMEOSTASIS; BONE MASS; CELL COUNT; CONTROLLED STUDY; EMBRYO; FEMALE; GENE DELETION; HOMEOSTASIS; MALE; MESENCHYME; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; PHENOTYPE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRABECULAR BONE; ANIMAL; BONE; CELL DIFFERENTIATION; DRUG ANTAGONISM; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENETICS; MESODERM; METABOLISM; PRENATAL DEVELOPMENT; STEM CELL;

METAZOA; MUS;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE AND BONES; CELL DIFFERENTIATION; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; MESODERM; MICE; NFATC TRANSCRIPTION FACTORS; OSTEOBLASTS; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84859237565     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002577     Document Type: Article

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