Assessment of the cytotoxic and apoptotic effects of chaetominine in a human leukemia cell line

Biomolecules and Therapeutics

Volumn 24, Issue 2, 2016, Pages 147-155

  Yao, Jingyun ^a,b   Jiao, Ruihua ^c   Liu, Changqing ^a,b   Zhang, Yupeng ^a,b   Yu, Wanguo ^a,b   Lu, Yanhua ^a,b   Tan, Renxiang ^c  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI COLLABORATIVE INNOVATION CENTER FOR BIOMANUFACTURING TECHNOLOGY   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

Apoptosis; Cytotoxic; K562 cell; Mitochondrial pathway

Indexed keywords

ALKALOID DERIVATIVE; ANTILEUKEMIC AGENT; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CELL DNA; CHAETOMININE; CYTOCHROME C; CYTOTOXIC AGENT; FLUOROURACIL; PROTEIN BAX; PROTEIN BCL 2; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL GROWTH; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG ISOLATION; ENZYME ACTIVATION; ENZYME RELEASE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC50; K562 CELL LINE; LEUKEMIA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; UPREGULATION;

EID: 84958987758     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2015.093     Document Type: Article

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