메뉴 건너뛰기




Volumn 23, Issue 5, 2015, Pages 407-413

Paraquat induces apoptosis through a mitochondria-dependent pathway in RAW264.7 cells

Author keywords

Apoptosis; Mitochondria; Paraquat; RAW264.7 cells; ROS

Indexed keywords

CASPASE 3; CYTOCHROME C; PARAQUAT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

EID: 84940388203     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2015.075     Document Type: Article
Times cited : (43)

References (40)
  • 1
    • 0029884044 scopus 로고    scopus 로고
    • Paraquat induced DNA damage by reactive oxygen species
    • Ali, S., Jain, S. K., Abdulla, M. and Athar, M. (1996) Paraquat induced DNA damage by reactive oxygen species. Biochem. Mol. Biol. Int. 39, 63-67.
    • (1996) Biochem. Mol. Biol. Int , vol.39 , pp. 63-67
    • Ali, S.1    Jain, S.K.2    Abdulla, M.3    Athar, M.4
  • 2
    • 0018607071 scopus 로고
    • Regulation of membrane peroxidation in health and disease
    • Boxer, L. A., Harris, R. E. and Baehner, R. L. (1979) Regulation of membrane peroxidation in health and disease. Pediatrics 64, 713-718.
    • (1979) Pediatrics , vol.64 , pp. 713-718
    • Boxer, L.A.1    Harris, R.E.2    Baehner, R.L.3
  • 3
    • 0032157954 scopus 로고    scopus 로고
    • Apoptosis in human lung epithelial cells: Triggering by paraquat and modulation by antioxidants
    • Cappelletti, G., Maggioni, M. G. and Maci, R. (1998) Apoptosis in human lung epithelial cells: triggering by paraquat and modulation by antioxidants. Cell Biol. Int. 22, 671-678.
    • (1998) Cell Biol. Int , vol.22 , pp. 671-678
    • Cappelletti, G.1    Maggioni, M.G.2    Maci, R.3
  • 5
    • 34347242465 scopus 로고    scopus 로고
    • Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain
    • Castello, P. R., Drechsel, D. A. and Patel, M. (2007) Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. J. Biol. Chem. 282, 14186-14193.
    • (2007) J. Biol. Chem , vol.282 , pp. 14186-14193
    • Castello, P.R.1    Drechsel, D.A.2    Patel, M.3
  • 6
    • 84940376271 scopus 로고    scopus 로고
    • Edaravone attenuates paraquat-induced lung injury by inhibiting oxidative stress in human type II alveolar epithelial cells
    • Cheng, Z. Q., Han, J. Y., Sun, P., Weng, Y. Y., Chen, J., Wu, G. Y. and Ma, H. X. (2012) Edaravone attenuates paraquat-induced lung injury by inhibiting oxidative stress in human type II alveolar epithelial cells. World J. Emerg. Med. 3, 55-59.
    • (2012) World J. Emerg. Med , vol.3 , pp. 55-59
    • Cheng, Z.Q.1    Han, J.Y.2    Sun, P.3    Weng, Y.Y.4    Chen, J.5    Wu, G.Y.6    Ma, H.X.7
  • 7
    • 33745950626 scopus 로고    scopus 로고
    • Mitochondrial outer membrane permeabilization during apoptosis: The innocent bystander scenario
    • Chipuk, J. E., Bouchier-Hayes, L. and Green, D. R. (2006) Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ. 13, 1396-1402.
    • (2006) Cell Death Differ , vol.13 , pp. 1396-1402
    • Chipuk, J.E.1    Bouchier-Hayes, L.2    Green, D.R.3
  • 8
    • 76049083966 scopus 로고    scopus 로고
    • Reactive oxygen species, cellular redox systems, and apoptosis
    • Circu, M. L. and Aw, T. Y. (2010) Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic. Biol. Med. 48, 749-762.
    • (2010) Free Radic. Biol. Med , vol.48 , pp. 749-762
    • Circu, M.L.1    Aw, T.Y.2
  • 9
    • 84885349259 scopus 로고    scopus 로고
    • Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway
    • Deng, S., Yuan, H., Yi, J., Lu, Y., Wei, Q., Guo, C., Wu, J., Yuan, L. and He, Z. (2013) Gossypol acetic acid induces apoptosis in RAW264.7 cells via a caspase-dependent mitochondrial signaling pathway. J. Vet. Sci. 14, 281-289.
    • (2013) J. Vet. Sci , vol.14 , pp. 281-289
    • Deng, S.1    Yuan, H.2    Yi, J.3    Lu, Y.4    Wei, Q.5    Guo, C.6    Wu, J.7    Yuan, L.8    He, Z.9
  • 10
    • 0035068237 scopus 로고    scopus 로고
    • Genotoxic effects of carbon black particles, diesel exhaust particles, and urban air particulates and their extracts on a human alveolar epithelial cell line (A549) and a human monocytic cell line (THP-1)
    • Don Porto Carero, A., Hoet, P. H., Verschaeve, L., Schoeters, G. and Nemery, B. (2001) Genotoxic effects of carbon black particles, diesel exhaust particles, and urban air particulates and their extracts on a human alveolar epithelial cell line (A549) and a human monocytic cell line (THP-1). Environ. Mol. Mutagen. 37, 155-163.
    • (2001) Environ. Mol. Mutagen , vol.37 , pp. 155-163
    • Don Porto Carero, A.1    Hoet, P.H.2    Verschaeve, L.3    Schoeters, G.4    Nemery, B.5
  • 11
    • 0031845839 scopus 로고    scopus 로고
    • Responses of alveolar macrophages and epithelial type II cells to oxidative DNA damage caused by paraquat
    • Dusinska, M., Kovacikova, Z., Vallova, B. and Collins, A. (1998) Responses of alveolar macrophages and epithelial type II cells to oxidative DNA damage caused by paraquat. Carcinogenesis 19, 809-812.
    • (1998) Carcinogenesis , vol.19 , pp. 809-812
    • Dusinska, M.1    Kovacikova, Z.2    Vallova, B.3    Collins, A.4
  • 12
    • 28244442462 scopus 로고    scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in human disease
    • Fadeel, B. and Orrenius, S. (2005) Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease. J. Intern. Med. 258, 479-517.
    • (2005) J. Intern. Med , vol.258 , pp. 479-517
    • Fadeel, B.1    Orrenius, S.2
  • 13
    • 0033576675 scopus 로고    scopus 로고
    • More than one way to die: Apoptosis, necrosis and reactive oxygen damage
    • Fiers, W., Beyaert, R., Declercq, W. and Vandenabeele, P. (1999) More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene 18, 7719-7730.
    • (1999) Oncogene , vol.18 , pp. 7719-7730
    • Fiers, W.1    Beyaert, R.2    Declercq, W.3    Vandenabeele, P.4
  • 14
    • 81055125652 scopus 로고    scopus 로고
    • Programmed cell death in animal development and disease
    • Fuchs, Y. and Steller, H. (2011) Programmed cell death in animal development and disease. Cell 147, 742-758.
    • (2011) Cell , vol.147 , pp. 742-758
    • Fuchs, Y.1    Steller, H.2
  • 15
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • Green, D. R. and Kroemer, G. (2004) The pathophysiology of mitochondrial cell death. Science 305, 626-629.
    • (2004) Science , vol.305 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 16
    • 0018775227 scopus 로고
    • Review of the toxicology of paraquat (1,1'-dimethyl-4,4'-bipyridinium chloride)
    • Haley, T. J. (1979) Review of the toxicology of paraquat (1,1'-dimethyl-4,4'-bipyridinium chloride). Clin. Toxicol. 14, 1-46.
    • (1979) Clin. Toxicol , vol.14 , pp. 1-46
    • Haley, T.J.1
  • 17
    • 0032937774 scopus 로고    scopus 로고
    • Effects of dietary antioxidants on the immune function of middle-aged adults
    • Hughes, D. A. (1999) Effects of dietary antioxidants on the immune function of middle-aged adults. Proc. Nutr. Soc. 58, 79-84.
    • (1999) Proc. Nutr. Soc , vol.58 , pp. 79-84
    • Hughes, D.A.1
  • 18
    • 84877784943 scopus 로고    scopus 로고
    • Correlations between BRCA1 defect and environmental factors in the risk of breast cancer
    • Kang, H. J., Hong, Y. B., Yi, Y. W., Cho, C. H., Wang, A. and Bae, I. (2013) Correlations between BRCA1 defect and environmental factors in the risk of breast cancer. J. Toxicol. Sci. 38, 355-361.
    • (2013) J. Toxicol. Sci , vol.38 , pp. 355-361
    • Kang, H.J.1    Hong, Y.B.2    Yi, Y.W.3    Cho, C.H.4    Wang, A.5    Bae, I.6
  • 19
    • 80053278810 scopus 로고    scopus 로고
    • Continuous hypoxia attenuates paraquat-induced cytotoxicity in the human A549 lung carcinoma cell line
    • Kim, H., Lee, S. W., Baek, K. M., Park, J. S. and Min, J. H. (2011) Continuous hypoxia attenuates paraquat-induced cytotoxicity in the human A549 lung carcinoma cell line. Exp. Mol. Med. 43, 494-500.
    • (2011) Exp. Mol. Med , vol.43 , pp. 494-500
    • Kim, H.1    Lee, S.W.2    Baek, K.M.3    Park, J.S.4    Min, J.H.5
  • 20
    • 0027502620 scopus 로고
    • Protection of a rat tracheal epithelial cell line from paraquat toxicity by inhibition of glucose-6-phosphate dehydrogenase
    • Lee, T. C., Lai, G. J., Kao, S. L., Ho, I. C. and Wu, C. W. (1993) Protection of a rat tracheal epithelial cell line from paraquat toxicity by inhibition of glucose-6-phosphate dehydrogenase. Biochem. Pharmacol. 45, 1143-1147.
    • (1993) Biochem. Pharmacol , vol.45 , pp. 1143-1147
    • Lee, T.C.1    Lai, G.J.2    Kao, S.L.3    Ho, I.C.4    Wu, C.W.5
  • 21
    • 0032983552 scopus 로고    scopus 로고
    • Paraquat induced activation of transcription factor AP-1 and apoptosis in PC12 cells
    • Li, X. and Sun, A. Y. (1999) Paraquat induced activation of transcription factor AP-1 and apoptosis in PC12 cells. J. Neural Transm. 106, 1-21.
    • (1999) J. Neural Transm , vol.106 , pp. 1-21
    • Li, X.1    Sun, A.Y.2
  • 22
  • 23
    • 84884699671 scopus 로고    scopus 로고
    • Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species-mediated mitochondrion-dependent pathway
    • Mao, Z., Xia, W., Wang, J., Chen, T., Zeng, Q., Xu, B., Li, W., Chen, X. and Xu, S. (2013) Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species-mediated mitochondrion-dependent pathway. J. Appl. Toxicol. 33, 1268-1276.
    • (2013) J. Appl. Toxicol , vol.33 , pp. 1268-1276
    • Mao, Z.1    Xia, W.2    Wang, J.3    Chen, T.4    Zeng, Q.5    Xu, B.6    Li, W.7    Chen, X.8    Xu, S.9
  • 24
    • 79960230433 scopus 로고    scopus 로고
    • Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics
    • Martinou, J. C. and Youle, R. J. (2011) Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics. Dev. Cell 21, 92-101.
    • (2011) Dev. Cell , vol.21 , pp. 92-101
    • Martinou, J.C.1    Youle, R.J.2
  • 25
    • 78149465001 scopus 로고    scopus 로고
    • Cytotoxicity and gene array analysis of alveolar epithelial A549 cells exposed to paraquat
    • Mitsopoulos, P. and Suntres, Z. E. (2010) Cytotoxicity and gene array analysis of alveolar epithelial A549 cells exposed to paraquat. Chem. Biol. Interact. 188, 427-436.
    • (2010) Chem. Biol. Interact , vol.188 , pp. 427-436
    • Mitsopoulos, P.1    Suntres, Z.E.2
  • 26
    • 79959231078 scopus 로고    scopus 로고
    • Protective effects of liposomal N-acetylcysteine against paraquat-induced cytotoxicity and gene expression
    • Mitsopoulos, P. and Suntres, Z. E. (2011) Protective effects of liposomal N-acetylcysteine against paraquat-induced cytotoxicity and gene expression. J. Toxicol. 2011, 808-967.
    • (2011) J. Toxicol , vol.2011 , pp. 808-967
    • Mitsopoulos, P.1    Suntres, Z.E.2
  • 27
    • 72049092384 scopus 로고    scopus 로고
    • Paraquat-induced oxidative stress response during amphibian early embryonic development
    • Mussi, M. A. and Calcaterra, N. B. (2010) Paraquat-induced oxidative stress response during amphibian early embryonic development. Comp. Biochem. Physiol. Toxicol. Pharmacol. 151, 240-247.
    • (2010) Comp. Biochem. Physiol. Toxicol. Pharmacol , vol.151 , pp. 240-247
    • Mussi, M.A.1    Calcaterra, N.B.2
  • 28
    • 1242315421 scopus 로고    scopus 로고
    • Evaluation of immunotoxicity induced by diazinon in C57bl/6 mice
    • Neishabouri, E. Z., Hassan, Z. M., Azizi, E. and Ostad, S. N. (2004) Evaluation of immunotoxicity induced by diazinon in C57bl/6 mice. Toxicology 196, 173-179.
    • (2004) Toxicology , vol.196 , pp. 173-179
    • Neishabouri, E.Z.1    Hassan, Z.M.2    Azizi, E.3    Ostad, S.N.4
  • 29
    • 1842767259 scopus 로고    scopus 로고
    • Mitochondrial regulation of apoptotic cell death
    • Orrenius, S. (2004) Mitochondrial regulation of apoptotic cell death. Toxicol. Lett. 149, 19-23.
    • (2004) Toxicol. Lett , vol.149 , pp. 19-23
    • Orrenius, S.1
  • 32
    • 41349098828 scopus 로고    scopus 로고
    • Paraquat induces apoptosis in human lymphocytes: Protective and rescue effects of glucose, cannabinoids and insulin-like growth factor-1
    • Rio, M. J. and Velez-Pardo, C. (2008) Paraquat induces apoptosis in human lymphocytes: protective and rescue effects of glucose, cannabinoids and insulin-like growth factor-1. Growth Factors 26, 49-60.
    • (2008) Growth Factors , vol.26 , pp. 49-60
    • Rio, M.J.1    Velez-Pardo, C.2
  • 34
    • 77956178738 scopus 로고    scopus 로고
    • MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity
    • Shi, L., Chen, J., Yang, J., Pan, T., Zhang, S. and Wang, Z. (2010) MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity. Brain Res. 1352, 255-264.
    • (2010) Brain Res , vol.1352 , pp. 255-264
    • Shi, L.1    Chen, J.2    Yang, J.3    Pan, T.4    Zhang, S.5    Wang, Z.6
  • 35
    • 0016157451 scopus 로고
    • Studies on the effects of paraquat and diquat on cells in culture. Viability of macrophages and fibroblasts incubated with paraquat and diquat
    • Styles, J. A. (1974) Studies on the effects of paraquat and diquat on cells in culture. Viability of macrophages and fibroblasts incubated with paraquat and diquat. Br. J. Exp. Pathol. 55, 71-77.
    • (1974) Br. J. Exp. Pathol , vol.55 , pp. 71-77
    • Styles, J.A.1
  • 36
    • 34247485841 scopus 로고    scopus 로고
    • Role of the mitochondrial membrane permeability transition in cell death
    • Tsujimoto, Y. and Shimizu, S. (2007) Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 12, 835-840.
    • (2007) Apoptosis , vol.12 , pp. 835-840
    • Tsujimoto, Y.1    Shimizu, S.2
  • 37
    • 0037240932 scopus 로고    scopus 로고
    • Regulation of macrophage function by the antioxidant N-acetylcysteine in mouseoxidative stress by endotoxin
    • Victor, V. M., Rocha, M. and De la Fuente, M. (2003) Regulation of macrophage function by the antioxidant N-acetylcysteine in mouseoxidative stress by endotoxin. Int. Immunopharmacol. 3, 97-106.
    • (2003) Int. Immunopharmacol , vol.3 , pp. 97-106
    • Victor, V.M.1    Rocha, M.2    De La Fuente, M.3
  • 38
    • 1642295733 scopus 로고    scopus 로고
    • Immune cells: Free radicals and antioxidants in sepsis
    • Victor, V. M., Rocha, M. and De la Fuente, M. (2004) Immune cells: free radicals and antioxidants in sepsis. Int. Immunopharmacol. 4, 327-347.
    • (2004) Int. Immunopharmacol , vol.4 , pp. 327-347
    • Victor, V.M.1    Rocha, M.2    De La Fuente, M.3
  • 39
    • 84899515092 scopus 로고    scopus 로고
    • Paraquat-induced reactive oxygen species inhibit neutrophil apoptosis via a p38 MAPK/NFkappaB-IL-6/TNF-alpha positive-feedback circuit
    • Wang, X., Luo, F. and Zhao, H. (2014) Paraquat-induced reactive oxygen species inhibit neutrophil apoptosis via a p38 MAPK/NFkappaB-IL-6/TNF-alpha positive-feedback circuit. PLoS One 9, e93837.
    • (2014) Plos One , vol.9
    • Wang, X.1    Luo, F.2    Zhao, H.3
  • 40
    • 0032944216 scopus 로고    scopus 로고
    • The polysaccharide portion of lipopolysaccharide regulates antigen-specific T-cell activation via effects on macrophage-mediated antigen processing
    • Zirk, N. M., Hashmi, S. F. and Ziegler, H. K. (1999) The polysaccharide portion of lipopolysaccharide regulates antigen-specific T-cell activation via effects on macrophage-mediated antigen processing. Infect. Immun. 67, 319-326.
    • (1999) Infect. Immun , vol.67 , pp. 319-326
    • Zirk, N.M.1    Hashmi, S.F.2    Ziegler, H.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.