Quantitative phosphoproteomics reveals genistein as a modulator of cell cycle and DNA damage response pathways in triple-negative breast cancer cells

International Journal of Oncology

Volumn 48, Issue 3, 2016, Pages 1016-1028

  Fang, Yi ^a   Zhang, Qian ^b   Wang, Xin ^a   Yang, Xue ^a   Wang, Xiangyu ^a   Huang, Zhen ^a   Jiao, Yuchen ^a   Wang, Jing ^a  

^a CANCER HOSPITAL   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Ataxia telangiectasia; BRCA1; CDK1; Cell cycle; DNA damage response; Genistein; Quantitative phosphoproteomics; Tandem mass tag; Triple negative breast cancer

Indexed keywords

BRCA1 PROTEIN; COHESIN; GENISTEIN; PHOSPHOPEPTIDE; PHOSPHOPROTEIN; TITANIUM DIOXIDE; ANTINEOPLASTIC AGENT; ISOFLAVONE DERIVATIVE; PROTEOME; TITANIUM;

ARTICLE; BIOINFORMATICS; CANCER PATIENT; CELL GROWTH; CENTROMERE; DNA DAMAGE; DNA REPLICATION; DRUG MECHANISM; HUMAN; HUMAN CELL; INVESTIGATIVE PROCEDURES; PHOSPHOPROTEOMICS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEOMICS; QUANTITATIVE STUDY; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; G2 PHASE CELL CYCLE CHECKPOINT; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR CELL LINE;

ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; DNA DAMAGE; DNA REPLICATION; G2 PHASE CELL CYCLE CHECKPOINTS; GENISTEIN; HUMANS; ISOFLAVONES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEOME; SIGNAL TRANSDUCTION; TITANIUM; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84958981763     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2016.3327     Document Type: Article

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