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Volumn 4, Issue 5, 2012, Pages 364-379

Nrf2 links epidermal barrier function with antioxidant defense

Author keywords

Barrier function; Inflammation; Nrf2; Oxidative stress; Skin

Indexed keywords

ANTIOXIDANT; ENVELOPE PROTEIN; LIPID; MITOGENIC AGENT; REACTIVE OXYGEN METABOLITE; SCAVENGER; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SMALL PROLINE RICH PROTEIN 2D; SMALL PROLINE RICH PROTEIN 2H; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

EID: 84860530952     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201200219     Document Type: Article
Times cited : (152)

References (64)
  • 3
    • 34249891333 scopus 로고    scopus 로고
    • Two neurons mediate diet-restriction-induced longevity in C. elegans
    • Bishop NA, Guarente L (2007) Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 447: 545-549.
    • (2007) Nature , vol.447 , pp. 545-549
    • Bishop, N.A.1    Guarente, L.2
  • 5
    • 33846924619 scopus 로고    scopus 로고
    • Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival
    • Cameron DJ, Tong Z, Yang Z, Kaminoh J, Kamiyah S, Chen H, Zeng J, Chen Y, Luo L, Zhang K (2007) Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival. Int J Biol Sci 3: 111-119.
    • (2007) Int J Biol Sci , vol.3 , pp. 111-119
    • Cameron, D.J.1    Tong, Z.2    Yang, Z.3    Kaminoh, J.4    Kamiyah, S.5    Chen, H.6    Zeng, J.7    Chen, Y.8    Luo, L.9    Zhang, K.10
  • 7
    • 40049088820 scopus 로고    scopus 로고
    • The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity
    • Copple IM, Goldring CE, Kitteringham NR, Park BK (2008) The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity. Toxicology 246: 24-33.
    • (2008) Toxicology , vol.246 , pp. 24-33
    • Copple, I.M.1    Goldring, C.E.2    Kitteringham, N.R.3    Park, B.K.4
  • 9
    • 66249095960 scopus 로고    scopus 로고
    • Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma
    • Demehri S, Morimoto M, Holtzman MJ, Kopan R (2009) Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma. PLoS Biol 7: e1000067.
    • (2009) PLoS Biol , vol.7
    • Demehri, S.1    Morimoto, M.2    Holtzman, M.J.3    Kopan, R.4
  • 13
    • 15544374581 scopus 로고    scopus 로고
    • Anti-inflammatory and antimicrobial roles of secretory leukocyte protease inhibitor
    • Doumas S, Kolokotronis A, Stefanopoulos P (2005) Anti-inflammatory and antimicrobial roles of secretory leukocyte protease inhibitor. Infect Immun 73: 1271-1274.
    • (2005) Infect Immun , vol.73 , pp. 1271-1274
    • Doumas, S.1    Kolokotronis, A.2    Stefanopoulos, P.3
  • 14
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30: 207-210.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 15
    • 77957895641 scopus 로고    scopus 로고
    • Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis
    • Elias PM (2010) Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis. Ann Dermatol 22: 245-254.
    • (2010) Ann Dermatol , vol.22 , pp. 245-254
    • Elias, P.M.1
  • 16
    • 44949151890 scopus 로고    scopus 로고
    • Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism
    • Elias PM, Williams ML, Holleran WM, Jiang YJ, Schmuth M (2008) Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism. J Lipid Res 49: 697-714.
    • (2008) J Lipid Res , vol.49 , pp. 697-714
    • Elias, P.M.1    Williams, M.L.2    Holleran, W.M.3    Jiang, Y.J.4    Schmuth, M.5
  • 18
    • 0029831031 scopus 로고    scopus 로고
    • Antileukoprotease inhibits stratum corneum chymotryptic enzyme. Evidence for a regulative function in desquamation
    • Franzke CW, Baici A, Bartels J, Christophers E, Wiedow O (1996) Antileukoprotease inhibits stratum corneum chymotryptic enzyme. Evidence for a regulative function in desquamation. J Biol Chem 271: 21886-21890.
    • (1996) J Biol Chem , vol.271 , pp. 21886-21890
    • Franzke, C.W.1    Baici, A.2    Bartels, J.3    Christophers, E.4    Wiedow, O.5
  • 19
    • 0037128938 scopus 로고    scopus 로고
    • Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice
    • Furuse M, Hata M, Furuse K, Yoshida Y, Haratake A, Sugitani Y, Noda T, Kubo A, Tsukita S (2002) Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol 156: 1099-1111.
    • (2002) J Cell Biol , vol.156 , pp. 1099-1111
    • Furuse, M.1    Hata, M.2    Furuse, K.3    Yoshida, Y.4    Haratake, A.5    Sugitani, Y.6    Noda, T.7    Kubo, A.8    Tsukita, S.9
  • 20
    • 76749132709 scopus 로고    scopus 로고
    • The key roles of elongases and desaturases in mammalian fatty acid metabolism: insights from transgenic mice
    • Guillou H, Zadravec D, Martin PG, Jacobsson A (2010) The key roles of elongases and desaturases in mammalian fatty acid metabolism: insights from transgenic mice. Prog Lipid Res 49: 186-199.
    • (2010) Prog Lipid Res , vol.49 , pp. 186-199
    • Guillou, H.1    Zadravec, D.2    Martin, P.G.3    Jacobsson, A.4
  • 22
    • 63549121490 scopus 로고    scopus 로고
    • NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
    • Hayes JD, McMahon M (2009) NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer. Trends Biochem Sci 34: 176-188.
    • (2009) Trends Biochem Sci , vol.34 , pp. 176-188
    • Hayes, J.D.1    McMahon, M.2
  • 23
    • 84886537141 scopus 로고    scopus 로고
    • Mendelian disorders of cornification (MEDOC): The ichthyoses.
    • Irvine A, Höger P, Yan A (Eds), Oxford, Blackwell Publishing Ltd
    • Hohl D, Williams M (2011) Mendelian disorders of cornification (MEDOC): The ichthyoses. In: Harper's Textbook of Pediatric Dermatology, Irvine A, Höger P, Yan A (Eds), Oxford, Blackwell Publishing Ltd.: pp 121.001-070.
    • (2011) Harper's Textbook of Pediatric Dermatology , pp. 121001-121070
    • Hohl, D.1    Williams, M.2
  • 26
    • 0343415084 scopus 로고    scopus 로고
    • Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier
    • Jensen JM, Schutze S, Forl M, Kronke M, Proksch E (1999) Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier. J Clin Invest 104: 1761-1770.
    • (1999) J Clin Invest , vol.104 , pp. 1761-1770
    • Jensen, J.M.1    Schutze, S.2    Forl, M.3    Kronke, M.4    Proksch, E.5
  • 27
    • 35448991707 scopus 로고    scopus 로고
    • Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex
    • Kerns ML, DePianto D, Dinkova-Kostova AT, Talalay P, Coulombe PA, (2007) Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex. Proc Natl Acad Sci USA 104: 14460-14465.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14460-14465
    • Kerns, M.L.1    DePianto, D.2    Dinkova-Kostova, A.T.3    Talalay, P.4    Coulombe, P.A.5
  • 29
    • 0034675890 scopus 로고    scopus 로고
    • Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein
    • Koch PJ, de Viragh PA, Scharer E, Bundman D, Longley MA, Bickenbach J, Kawachi Y, Suga Y, Zhou Z, Huber M, et al (2000) Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J Cell Biol 151: 389-400.
    • (2000) J Cell Biol , vol.151 , pp. 389-400
    • Koch, P.J.1    de Viragh, P.A.2    Scharer, E.3    Bundman, D.4    Longley, M.A.5    Bickenbach, J.6    Kawachi, Y.7    Suga, Y.8    Zhou, Z.9    Huber, M.10
  • 30
    • 77953228968 scopus 로고    scopus 로고
    • Nrf2-Keap1 signaling as a potential target for chemoprevention of inflammation-associated carcinogenesis
    • Kundu JK, Surh YJ (2010) Nrf2-Keap1 signaling as a potential target for chemoprevention of inflammation-associated carcinogenesis. Pharm Res 27: 999-1013.
    • (2010) Pharm Res , vol.27 , pp. 999-1013
    • Kundu, J.K.1    Surh, Y.J.2
  • 31
    • 77649270763 scopus 로고    scopus 로고
    • Targeting NRF2 signaling for cancer chemoprevention
    • Kwak MK, Kensler TW (2010) Targeting NRF2 signaling for cancer chemoprevention. Toxicol Appl Pharmacol 244: 66-76.
    • (2010) Toxicol Appl Pharmacol , vol.244 , pp. 66-76
    • Kwak, M.K.1    Kensler, T.W.2
  • 32
    • 0042818179 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids activate transglutaminases in situ and induce cornification of epidermal keratinocytes
    • Ladd PA, Du L, Capdevila JH, Mernaugh R, Keeney DS (2003) Epoxyeicosatrienoic acids activate transglutaminases in situ and induce cornification of epidermal keratinocytes. J Biol Chem 278: 35184-35192.
    • (2003) J Biol Chem , vol.278 , pp. 35184-35192
    • Ladd, P.A.1    Du, L.2    Capdevila, J.H.3    Mernaugh, R.4    Keeney, D.S.5
  • 33
    • 33846903325 scopus 로고    scopus 로고
    • Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice
    • Li W, Sandhoff R, Kono M, Zerfas P, Hoffmann V, Ding BC, Proia RL, Deng CX (2007) Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice. Int J Biol Sci 3: 120-128.
    • (2007) Int J Biol Sci , vol.3 , pp. 120-128
    • Li, W.1    Sandhoff, R.2    Kono, M.3    Zerfas, P.4    Hoffmann, V.5    Ding, B.C.6    Proia, R.L.7    Deng, C.X.8
  • 34
    • 34247526984 scopus 로고    scopus 로고
    • Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer
    • Liby KT, Yore MM, Sporn MB (2007) Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat Rev Cancer 7: 357-369.
    • (2007) Nat Rev Cancer , vol.7 , pp. 357-369
    • Liby, K.T.1    Yore, M.M.2    Sporn, M.B.3
  • 35
    • 77951279075 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer
    • Liou GY, Storz P (2010) Reactive oxygen species in cancer. Free Radic Res 44: 479-496.
    • (2010) Free Radic Res , vol.44 , pp. 479-496
    • Liou, G.Y.1    Storz, P.2
  • 38
    • 0037326928 scopus 로고    scopus 로고
    • Mouse Sprr locus: a tandem array of coordinately regulated genes
    • Patel S, Kartasova T, Segre JA (2003) Mouse Sprr locus: a tandem array of coordinately regulated genes. Mamm Genome 14: 140-148.
    • (2003) Mamm Genome , vol.14 , pp. 140-148
    • Patel, S.1    Kartasova, T.2    Segre, J.A.3
  • 39
    • 70449469039 scopus 로고    scopus 로고
    • Reactive species and diabetes: counteracting oxidative stress to improve health
    • Perez-Matute P, Zulet MA, Martinez JA (2009) Reactive species and diabetes: counteracting oxidative stress to improve health. Curr Opin Pharmacol 9: 771-779.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 771-779
    • Perez-Matute, P.1    Zulet, M.A.2    Martinez, J.A.3
  • 40
  • 42
    • 0035853157 scopus 로고    scopus 로고
    • Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
    • Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW (2001) Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 98: 3410-3415.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3410-3415
    • Ramos-Gomez, M.1    Kwak, M.K.2    Dolan, P.M.3    Itoh, K.4    Yamamoto, M.5    Talalay, P.6    Kensler, T.W.7
  • 43
    • 53249154670 scopus 로고    scopus 로고
    • Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling
    • Reddy NM, Kleeberger SR, Bream JH, Fallon PG, Kensler TW, Yamamoto M, Reddy SP (2008) Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling. Oncogene 27: 5821-5832.
    • (2008) Oncogene , vol.27 , pp. 5821-5832
    • Reddy, N.M.1    Kleeberger, S.R.2    Bream, J.H.3    Fallon, P.G.4    Kensler, T.W.5    Yamamoto, M.6    Reddy, S.P.7
  • 44
    • 0025948113 scopus 로고
    • The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
    • Rushmore TH, Morton MR, Pickett CB (1991) The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266: 11632-11639.
    • (1991) J Biol Chem , vol.266 , pp. 11632-11639
    • Rushmore, T.H.1    Morton, M.R.2    Pickett, C.B.3
  • 45
    • 67649838095 scopus 로고    scopus 로고
    • Filaggrin in the frontline: role in skin barrier function and disease
    • Sandilands A, Sutherland C, Irvine AD, McLean WH (2009) Filaggrin in the frontline: role in skin barrier function and disease. J Cell Sci 122: 1285-1294.
    • (2009) J Cell Sci , vol.122 , pp. 1285-1294
    • Sandilands, A.1    Sutherland, C.2    Irvine, A.D.3    McLean, W.H.4
  • 46
    • 0032505716 scopus 로고    scopus 로고
    • A composite CMV-IE enhancer/beta-actin promoter is ubiquitously expressed in mouse cutaneous epithelium
    • Sawicki JA, Morris RJ, Monks B, Sakai K, Miyazaki J (1998) A composite CMV-IE enhancer/beta-actin promoter is ubiquitously expressed in mouse cutaneous epithelium. Exp Cell Res 244: 367-369.
    • (1998) Exp Cell Res , vol.244 , pp. 367-369
    • Sawicki, J.A.1    Morris, R.J.2    Monks, B.3    Sakai, K.4    Miyazaki, J.5
  • 50
    • 77953012548 scopus 로고    scopus 로고
    • Stress-activated cap'n'collar transcription factors in aging and human disease
    • Sykiotis GP, Bohmann D (2010) Stress-activated cap'n'collar transcription factors in aging and human disease. Sci Signal 3: re3.
    • (2010) Sci Signal , vol.3
    • Sykiotis, G.P.1    Bohmann, D.2
  • 54
    • 79958808930 scopus 로고    scopus 로고
    • ROS quenching potential of the epidermal cornified cell envelope
    • Vermeij WP, Alia A, Backendorf C (2011) ROS quenching potential of the epidermal cornified cell envelope. J Invest Dermatol 131: 1435-1441.
    • (2011) J Invest Dermatol , vol.131 , pp. 1435-1441
    • Vermeij, W.P.1    Alia, A.2    Backendorf, C.3
  • 58
    • 34247192531 scopus 로고    scopus 로고
    • Keratinocyte-fibroblast interactions in wound healing
    • Werner S, Krieg T, Smola H (2007) Keratinocyte-fibroblast interactions in wound healing. J Invest Dermatol 127: 998-1008.
    • (2007) J Invest Dermatol , vol.127 , pp. 998-1008
    • Werner, S.1    Krieg, T.2    Smola, H.3
  • 60
    • 78249233244 scopus 로고    scopus 로고
    • Antimicrobial peptides: the ancient arm of the human immune system
    • Wiesner J, Vilcinskas A (2010) Antimicrobial peptides: the ancient arm of the human immune system. Virulence 1: 440-464.
    • (2010) Virulence , vol.1 , pp. 440-464
    • Wiesner, J.1    Vilcinskas, A.2
  • 61
    • 0026706275 scopus 로고
    • Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice
    • Wood LC, Jackson SM, Elias PM, Grunfeld C, Feingold KR (1992) Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Clin Invest 90: 482-487.
    • (1992) J Clin Invest , vol.90 , pp. 482-487
    • Wood, L.C.1    Jackson, S.M.2    Elias, P.M.3    Grunfeld, C.4    Feingold, K.R.5
  • 62
    • 33748089664 scopus 로고    scopus 로고
    • Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2
    • Xu C, Huang MT, Shen G, Yuan X, Lin W, Khor TO, Conney AH, Kong AN (2006) Inhibition of 7, 12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2. Cancer Res 66: 8293-8296.
    • (2006) Cancer Res , vol.66 , pp. 8293-8296
    • Xu, C.1    Huang, M.T.2    Shen, G.3    Yuan, X.4    Lin, W.5    Khor, T.O.6    Conney, A.H.7    Kong, A.N.8


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