Kaempferol induces apoptosis in HepG2 cells via activation of the endoplasmic reticulum stress pathway

Molecular Medicine Reports

Volumn 13, Issue 3, 2016, Pages 2791-2800

  Guo, Haiqing ^a   Ren, Feng ^b   Zhang, Li ^c   Zhang, Xiangying ^b   Yang, Rongrong ^b   Xie, Bangxiang ^b   Li, Zhuo ^b   Hu, Zhongjie ^a   Duan, Zhongping ^a   Zhang, Jing ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; C EBP homologous protein; Endoplasmic reticulum stress; Hepatocellular carcinoma cell; Kaempferol

Indexed keywords

4 PHENYL BUTYRIC ACID; ACTIVATING TRANSCRIPTION FACTOR 6; BUTYRIC ACID DERIVATIVE; CASPASE 3; CASPASE 4; CCAAT ENHANCER BINDING PROTEIN; ENZYME; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; INOSITOL REQUIRING ENZYME 1 ALPHA; KAEMPFEROL; LACTATE DEHYDROGENASE; PROTEIN KINASE R; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DDIT3 PROTEIN, HUMAN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; KAEMPFEROL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GENETIC TRANSFECTION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PLASMID; PROTEIN EXPRESSION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HEP-G2 CELL LINE; IC50; METABOLISM; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOPLASMIC RETICULUM STRESS; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; KAEMPFEROLS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 84958721746     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2016.4845     Document Type: Article

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