-
1
-
-
41149099559
-
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
-
Sarkar S, Kalia V, Haining WN, Konieczny BT, Subramaniam S, Ahmed R. Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J Exp Med 2008; 205:625-40.
-
(2008)
J Exp Med
, vol.205
, pp. 625-640
-
-
Sarkar, S.1
Kalia, V.2
Haining, W.N.3
Konieczny, B.T.4
Subramaniam, S.5
Ahmed, R.6
-
2
-
-
77955035480
-
Early events governing memory CD8 T-cell differentiation
-
Obar JJ, Lefrancois L. Early events governing memory CD8 T-cell differentiation. Int Immunol 2010; 22:619-25.
-
(2010)
Int Immunol
, vol.22
, pp. 619-625
-
-
Obar, J.J.1
Lefrancois, L.2
-
5
-
-
0347382593
-
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
-
Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 2003; 4:1191-8.
-
(2003)
Nat Immunol
, vol.4
, pp. 1191-1198
-
-
Kaech, S.M.1
Tan, J.T.2
Wherry, E.J.3
Konieczny, B.T.4
Surh, C.D.5
Ahmed, R.6
-
11
-
-
75649136214
-
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
-
Crotty S, Johnston RJ, Schoenberger SP. Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat Immunol 2010; 11:114-20.
-
(2010)
Nat Immunol
, vol.11
, pp. 114-120
-
-
Crotty, S.1
Johnston, R.J.2
Schoenberger, S.P.3
-
14
-
-
84886720433
-
The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells
-
Man K, Miasari M, Shi W, Xin A, Henstridge DC, Preston S et al. The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells. Nat Immunol 2013; 14:1155-65.
-
(2013)
Nat Immunol
, vol.14
, pp. 1155-1165
-
-
Man, K.1
Miasari, M.2
Shi, W.3
Xin, A.4
Henstridge, D.C.5
Preston, S.6
-
18
-
-
67650074206
-
mTOR regulates memory CD8 T-cell differentiation
-
Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF et al. mTOR regulates memory CD8 T-cell differentiation. Nature 2009; 460:108-12.
-
(2009)
Nature
, vol.460
, pp. 108-112
-
-
Araki, K.1
Turner, A.P.2
Shaffer, V.O.3
Gangappa, S.4
Keller, S.A.5
Bachmann, M.F.6
-
19
-
-
66949173728
-
mTOR differentially regulates effector and regulatory T cell lineage commitment
-
Delgoffe GM, Kole TP, Zheng Y, Zarek PE, Matthews KL, Xiao B et al. mTOR differentially regulates effector and regulatory T cell lineage commitment. Immunity 2009; 30:832-44.
-
(2009)
Immunity
, vol.30
, pp. 832-844
-
-
Delgoffe, G.M.1
Kole, T.P.2
Zheng, Y.3
Zarek, P.E.4
Matthews, K.L.5
Xiao, B.6
-
20
-
-
77951678634
-
The role of mTOR in memory CD8 T-cell differentiation
-
Araki K, Youngblood B, Ahmed R. The role of mTOR in memory CD8 T-cell differentiation. Immunol Rev 2010; 235:234-43.
-
(2010)
Immunol Rev
, vol.235
, pp. 234-243
-
-
Araki, K.1
Youngblood, B.2
Ahmed, R.3
-
21
-
-
74649085700
-
+ T cell fate by regulating the expression of transcription factors T-bet and eomesodermin
-
+ T cell fate by regulating the expression of transcription factors T-bet and eomesodermin. Immunity 2010; 32:67-78.
-
(2010)
Immunity
, vol.32
, pp. 67-78
-
-
Rao, R.R.1
Li, Q.2
Odunsi, K.3
Shrikant, P.A.4
-
23
-
-
84860237060
-
Regulation and function of mTOR signalling in T cell fate decisions
-
Chi H. Regulation and function of mTOR signalling in T cell fate decisions. Nat Rev Immunol 2012; 12:325-38.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 325-338
-
-
Chi, H.1
-
24
-
-
84926631707
-
mTOR links environmental signals to T cell fate decisions
-
Chapman NM, Chi H. mTOR links environmental signals to T cell fate decisions. Front Immunol 2015; 5:686.
-
(2015)
Front Immunol
, vol.5
, pp. 686
-
-
Chapman, N.M.1
Chi, H.2
-
27
-
-
84892941233
-
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity
-
Berezhnoy A, Castro I, Levay A, Malek TR, Gilboa E. Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity. J Clin Invest 2014; 124:188-97.
-
(2014)
J Clin Invest
, vol.124
, pp. 188-197
-
-
Berezhnoy, A.1
Castro, I.2
Levay, A.3
Malek, T.R.4
Gilboa, E.5
-
28
-
-
84903136755
-
Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection
-
Krishna S, Yang J, Wang H, Qiu Y, Zhong XP. Role of tumor suppressor TSC1 in regulating antigen-specific primary and memory CD8 T cell responses to bacterial infection. Infect Immun 2014; 82:3045-57.
-
(2014)
Infect Immun
, vol.82
, pp. 3045-3057
-
-
Krishna, S.1
Yang, J.2
Wang, H.3
Qiu, Y.4
Zhong, X.P.5
-
29
-
-
77949423735
-
Regulating functional cell fates in CD8 T cells
-
Shrikant PA, Rao R, Li Q, Kesterson J, Eppolito C, Mischo A et al. Regulating functional cell fates in CD8 T cells. Immunol Res 2010; 46:12-22.
-
(2010)
Immunol Res
, vol.46
, pp. 12-22
-
-
Shrikant, P.A.1
Rao, R.2
Li, Q.3
Kesterson, J.4
Eppolito, C.5
Mischo, A.6
-
32
-
-
74549216531
-
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
-
Pipkin ME, Sacks JA, Cruz-Guilloty F, Lichtenheld MG, Bevan MJ, Rao A. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 2010; 32:79-90.
-
(2010)
Immunity
, vol.32
, pp. 79-90
-
-
Pipkin, M.E.1
Sacks, J.A.2
Cruz-Guilloty, F.3
Lichtenheld, M.G.4
Bevan, M.J.5
Rao, A.6
-
34
-
-
77951683908
-
Effect of NKG2D ligand expression on host immune responses
-
Champsaur M, Lanier LL. Effect of NKG2D ligand expression on host immune responses. Immunol Rev 2011; 235:267-85.
-
(2011)
Immunol Rev
, vol.235
, pp. 267-285
-
-
Champsaur, M.1
Lanier, L.L.2
-
36
-
-
34447099969
-
Regulation of ligands for the activating receptor NKG2D
-
Mistry AR, O'Callaghan CA. Regulation of ligands for the activating receptor NKG2D. Immunology 2007; 121:439-47.
-
(2007)
Immunology
, vol.121
, pp. 439-447
-
-
Mistry, A.R.1
O'Callaghan, C.A.2
-
37
-
-
0035286345
-
Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells
-
Groh V, Rhinehart R, Randolph-Habecker J, Topp MS, Riddell SR, Spies T. Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nat Immunol 2001; 2:255-60.
-
(2001)
Nat Immunol
, vol.2
, pp. 255-260
-
-
Groh, V.1
Rhinehart, R.2
Randolph-Habecker, J.3
Topp, M.S.4
Riddell, S.R.5
Spies, T.6
-
40
-
-
84961879643
-
NKG2D receptor and its ligands in host defense
-
Lanier LL. NKG2D receptor and its ligands in host defense. Cancer Immunol Res 2015; 3:575-82.
-
(2015)
Cancer Immunol Res
, vol.3
, pp. 575-582
-
-
Lanier, L.L.1
-
41
-
-
79952768178
-
Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells
-
Benitez AC, Dai Z, Mann HH, Reeves RS, Margineantu DH, Gooley TA et al. Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells. Proc Natl Acad Sci USA 2011; 108:4081-6.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4081-4086
-
-
Benitez, A.C.1
Dai, Z.2
Mann, H.H.3
Reeves, R.S.4
Margineantu, D.H.5
Gooley, T.A.6
-
42
-
-
84860342013
-
Signal integration by Akt regulates CD8 T cell effector and memory differentiation
-
Kim EH, Sullivan JA, Plisch EH, Tejera MM, Jatzek A, Choi KY et al. Signal integration by Akt regulates CD8 T cell effector and memory differentiation. J Immunol 2012; 188:4305-14.
-
(2012)
J Immunol
, vol.188
, pp. 4305-4314
-
-
Kim, E.H.1
Sullivan, J.A.2
Plisch, E.H.3
Tejera, M.M.4
Jatzek, A.5
Choi, K.Y.6
-
43
-
-
33644556146
-
Prolonged TCR/CD28 engagement drives IL-2- independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin
-
Colombetti S, Basso V, Mueller DL, Mondino A. Prolonged TCR/CD28 engagement drives IL-2- independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin. J Immunol 2006; 176:2730-8.
-
(2006)
J Immunol
, vol.176
, pp. 2730-2738
-
-
Colombetti, S.1
Basso, V.2
Mueller, D.L.3
Mondino, A.4
-
44
-
-
33744545472
-
NKG2D-mediated activation of cytotoxic lymphocytes: unique signaling pathways and distinct functional outcomes
-
Upshaw JL, Leibson PJ. NKG2D-mediated activation of cytotoxic lymphocytes: unique signaling pathways and distinct functional outcomes. Semin Immunol 2006; 18:167-75.
-
(2006)
Semin Immunol
, vol.18
, pp. 167-175
-
-
Upshaw, J.L.1
Leibson, P.J.2
-
46
-
-
79959240911
-
NKG2D receptor regulates human effector T-cell cytokine production
-
Barber A, Sentman CL. NKG2D receptor regulates human effector T-cell cytokine production. Blood 2011; 117:6571-81.
-
(2011)
Blood
, vol.117
, pp. 6571-6581
-
-
Barber, A.1
Sentman, C.L.2
-
48
-
-
84875807707
-
Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner
-
Chu T, Tyznik AJ, Roepke S, Berkley AM, Woodward-Davis A, Pattacini L et al. Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner. Cell Rep 2013; 3:701-8.
-
(2013)
Cell Rep
, vol.3
, pp. 701-708
-
-
Chu, T.1
Tyznik, A.J.2
Roepke, S.3
Berkley, A.M.4
Woodward-Davis, A.5
Pattacini, L.6
-
49
-
-
84880684352
-
NKG2D induces Mcl-1 expression and mediates survival of CD8 memory T cell precursors via phosphatidylinositol 3-kinase
-
Wensveen FM, Lenartic M, Jelencic V, Lemmermann NA, ten Brinke A, Jonjic S et al. NKG2D induces Mcl-1 expression and mediates survival of CD8 memory T cell precursors via phosphatidylinositol 3-kinase. J Immunol 2013; 191:1307-15.
-
(2013)
J Immunol
, vol.191
, pp. 1307-1315
-
-
Wensveen, F.M.1
Lenartic, M.2
Jelencic, V.3
Lemmermann, N.A.4
ten Brinke, A.5
Jonjic, S.6
-
51
-
-
84871483253
-
All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells
-
Gamper CJ, Powell JD. All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells. Front Immunol 2012; 3:312.
-
(2012)
Front Immunol
, vol.3
, pp. 312
-
-
Gamper, C.J.1
Powell, J.D.2
-
52
-
-
84874271196
-
mTOR, linking metabolism and immunity
-
Xu X, Ye L, Araki K, Ahmed R. mTOR, linking metabolism and immunity. Semin Immunol 2012; 24:429-35.
-
(2012)
Semin Immunol
, vol.24
, pp. 429-435
-
-
Xu, X.1
Ye, L.2
Araki, K.3
Ahmed, R.4
-
53
-
-
84926670025
-
Environmental and metabolic sensors that control T cell biology
-
Ramsay G, Cantrell D. Environmental and metabolic sensors that control T cell biology. Front Immunol 2015; 6:99.
-
(2015)
Front Immunol
, vol.6
, pp. 99
-
-
Ramsay, G.1
Cantrell, D.2
-
54
-
-
0035135841
-
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
-
Brunet A, Justin P, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol Cell Biol 2001; 21:952-65.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 952-965
-
-
Brunet, A.1
Justin, P.2
Tran, H.3
Hu, L.S.4
Hemmings, B.A.5
Greenberg, M.E.6
-
55
-
-
33748153690
-
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
-
Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X et al. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 2006; 126:955-68.
-
(2006)
Cell
, vol.126
, pp. 955-968
-
-
Inoki, K.1
Ouyang, H.2
Zhu, T.3
Lindvall, C.4
Wang, Y.5
Zhang, X.6
-
56
-
-
75149140113
-
Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1
-
Di Pietro N, Panel V, Hayes S, Bagattin A, Meruvu S, Pandolfi A et al. Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1. Mol Endocrinol 2010; 24:370-80.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 370-380
-
-
Di Pietro, N.1
Panel, V.2
Hayes, S.3
Bagattin, A.4
Meruvu, S.5
Pandolfi, A.6
-
57
-
-
84899094151
-
The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex
-
Heikamp EB, Patel CH, Collins S, Waickman A, Oh MH, Sun IH et al. The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex. Nat Immunol 2014; 15:457-64.
-
(2014)
Nat Immunol
, vol.15
, pp. 457-464
-
-
Heikamp, E.B.1
Patel, C.H.2
Collins, S.3
Waickman, A.4
Oh, M.H.5
Sun, I.H.6
-
58
-
-
84876798411
-
Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1
-
Wu C, Yosef N, Thalhamer T, Zhu C, Xiao S, Kishi Y et al. Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Nature 2013; 496:513-7.
-
(2013)
Nature
, vol.496
, pp. 513-517
-
-
Wu, C.1
Yosef, N.2
Thalhamer, T.3
Zhu, C.4
Xiao, S.5
Kishi, Y.6
-
59
-
-
84902349685
-
mTOR signaling and transcriptional regulation in T lymphocytes
-
Zeng H, Chi H. mTOR signaling and transcriptional regulation in T lymphocytes. Transcription 2014; 5:e28263.
-
(2014)
Transcription
, vol.5
, pp. e28263
-
-
Zeng, H.1
Chi, H.2
-
60
-
-
65949113601
-
Targeting mTOR with rapamycin: one dose does not fit all
-
Foster DA, Toschi A. Targeting mTOR with rapamycin: one dose does not fit all. Cell Cycle 2009; 8:1026-9.
-
(2009)
Cell Cycle
, vol.8
, pp. 1026-1029
-
-
Foster, D.A.1
Toschi, A.2
-
61
-
-
20444429440
-
TCR engagement increases hypoxia-inducible factor-1α protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells
-
Nakamura H, Makino Y, Okamoto K, Poellinger L, Ohnuma K, Morimoto C et al. TCR engagement increases hypoxia-inducible factor-1α protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells. J Immunol 2005; 174:7592-9.
-
(2005)
J Immunol
, vol.174
, pp. 7592-7599
-
-
Nakamura, H.1
Makino, Y.2
Okamoto, K.3
Poellinger, L.4
Ohnuma, K.5
Morimoto, C.6
-
62
-
-
36348955143
-
Chimeric NKG2D modified T cells inhibit systemic T-cell lymphoma growth in a manner involving multiple cytokines and cytotoxic pathways
-
Zhang T, Barber A, Sentman CL. Chimeric NKG2D modified T cells inhibit systemic T-cell lymphoma growth in a manner involving multiple cytokines and cytotoxic pathways. Cancer Res 2007; 67:11029-36.
-
(2007)
Cancer Res
, vol.67
, pp. 11029-11036
-
-
Zhang, T.1
Barber, A.2
Sentman, C.L.3
-
64
-
-
80051919119
-
Β-catenin is dispensable for T cell effector differentiation, memory formation, and recall responses
-
Prlic M, Bevan MJ. Β-catenin is dispensable for T cell effector differentiation, memory formation, and recall responses. J Immunol 2011; 187:1542-6.
-
(2011)
J Immunol
, vol.187
, pp. 1542-1546
-
-
Prlic, M.1
Bevan, M.J.2
-
65
-
-
84903643113
-
Differential impact of CD27 and 4-1BB costimulation on effector and memory CD8 T cell generation following peptide immunization
-
Willoughby JE, Kerr JP, Rogel A, Taraban VY, Buchan SL, Johnson PW et al. Differential impact of CD27 and 4-1BB costimulation on effector and memory CD8 T cell generation following peptide immunization. J Immunol 2014; 193:244-51.
-
(2014)
J Immunol
, vol.193
, pp. 244-251
-
-
Willoughby, J.E.1
Kerr, J.P.2
Rogel, A.3
Taraban, V.Y.4
Buchan, S.L.5
Johnson, P.W.6
-
66
-
-
84858124795
-
Targeting costimulatory molecules to improve antitumor immunity
-
Capece D, Verzella D, Fischietti M, Zazzeroni F, Alesse E. Targeting costimulatory molecules to improve antitumor immunity. J Biomed Biotechnol 2012; 2012:e926321.
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. e926321
-
-
Capece, D.1
Verzella, D.2
Fischietti, M.3
Zazzeroni, F.4
Alesse, E.5
-
67
-
-
84928565398
-
Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy
-
Figueroa JA, Reidy A, Mirandola L, Trotter K, Suvorava N, Figueroa A et al. Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy. Rev Immunol 2015; 34:154-87.
-
(2015)
Rev Immunol
, vol.34
, pp. 154-187
-
-
Figueroa, J.A.1
Reidy, A.2
Mirandola, L.3
Trotter, K.4
Suvorava, N.5
Figueroa, A.6
-
68
-
-
40449117478
-
Immunotherapy with chimeric NKG2D receptors leads to long-term tumor-free survival and development of host antitumor immunity in murine ovarian cancer
-
Barber A, Zhang T, Sentman CL. Immunotherapy with chimeric NKG2D receptors leads to long-term tumor-free survival and development of host antitumor immunity in murine ovarian cancer. J Immunol 2008; 180:72-8.
-
(2008)
J Immunol
, vol.180
, pp. 72-78
-
-
Barber, A.1
Zhang, T.2
Sentman, C.L.3
-
69
-
-
78649899880
-
Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties
-
Slavuljica I, Busche A, Babić M, Mitrovic M, Gasparovic I, Cekinovic D et al. Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties. J Clin Invest 2010; 120:4532-45.
-
(2010)
J Clin Invest
, vol.120
, pp. 4532-4545
-
-
Slavuljica, I.1
Busche, A.2
Babić, M.3
Mitrovic, M.4
Gasparovic, I.5
Cekinovic, D.6
-
70
-
-
84885332569
-
Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ
-
Trsan T, Busche A, Abram M, Wensveen FM, Lemmermann NA, Arapovic M et al. Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ. Proc Natl Acad Sci USA 2013; 110:16550-5.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 16550-16555
-
-
Trsan, T.1
Busche, A.2
Abram, M.3
Wensveen, F.M.4
Lemmermann, N.A.5
Arapovic, M.6
|