Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase

Science Translational Medicine

Volumn 8, Issue 325, 2016, Pages

  Jarrett, Rachael ^a   Salio, Mariolina ^a   Lloyd Lavery, Antonia ^a   Subramaniam, Sumithra ^a   Bourgeois, Elvire ^b   Archer, Charles ^a   Cheung, Ka Lun ^a   Hardman, Clare ^a   Chandler, David ^a   Salimi, Maryam ^a   Gutowska Owsiak, Danuta ^a   De La Serna, Jorge Bernardino ^a   Fallon, Padraic G ^c,d,e   Jolin, Helen ^f   McKenzie, Andrew ^f   Dziembowski, Andrzej ^g   Podobas, Ewa Izabela ^g   Bal, Wojciech ^g   Johnson, David ^h   Moody, D Branch ^b   Cerundolo, Vincenzo ^a   Ogg, Graham ^a   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d ST JAMES S HOSPITAL   (Ireland)

^e OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^f MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^g INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^h UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FILAGGRIN; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HOUSE DUST ALLERGEN; INTERLEUKIN 13; PHOSPHOLIPASE; PHOSPHOLIPASE A2; T6 ANTIGEN; CD1 ANTIGEN; CYTOKINE; INTERMEDIATE FILAMENT PROTEIN; PHOSPHOLIPASE A2 GROUP IV;

ADAPTIVE IMMUNITY; ALLOIMMUNITY; ANTIGEN PRESENTATION; ARTICLE; ATOPIC DERMATITIS; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DERMATOPHAGOIDES; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; PRIORITY JOURNAL; PROTEIN FUNCTION; SKIN BIOPSY; T LYMPHOCYTE ACTIVATION; ADOLESCENT; ADULT; AGED; ANIMAL; BLOOD; CELL SEPARATION; DRUG EFFECTS; ENZYMOLOGY; IMMUNOLOGY; K-562 CELL LINE; METABOLISM; MIDDLE AGED; PATHOLOGY; PYROGLYPHIDAE; SKIN; T LYMPHOCYTE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANIMALS; ANTIGENS, CD1; CELL SEPARATION; CYTOKINES; DERMATITIS, ATOPIC; GROUP IV PHOSPHOLIPASES A2; HUMANS; INTERMEDIATE FILAMENT PROTEINS; K562 CELLS; MIDDLE AGED; PYROGLYPHIDAE; SKIN; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84958617542     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aad6833     Document Type: Article

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