A possible mechanism underlying the ceramide deficiency in atopic dermatitis: Expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide

Journal of Dermatological Science

Volumn 55, Issue 1, 2009, Pages 1-9

  Imokawa, Genji ^a  

^a TOKYO UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

Glucocerebrosidase; Atopic dermatitis; Barrier function; Ceramide; Glucosylceramide; Glucosylsphingosine; Sphingomyelinase, Sphingomyeline glucosylceramide deacylase, Sphingosylphosphorylcholine; Sphingomyeline; Water holding property

Indexed keywords

ACYLSPHINGOSINE DEACYLASE; GLUCOSYLCERAMIDASE; GLUCOSYLCERAMIDE; GLUCOSYLCERAMIDE DEACYLASE; GLUCOSYLSPHINGOSINE; HYDROLASE; SERINE PALMITOYLTRANSFERASE; SPHINGOMYELIN; SPHINGOMYELIN DEACYLASE; SPHINGOMYELIN GLUCOSYLCERAMIDE DEACYLASE; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE DERIVATIVE; SPHINGOSYLPHOSPHORYLCHOLINE; UNCLASSIFIED DRUG;

ATOPIC DERMATITIS; CERAMIDE DEFICIENCY; CONTACT DERMATITIS; ENZYME ACTIVITY; ENZYME DEFECT; EPIDERMIS; HUMAN; LIPID HYDROLYSIS; MOLECULAR WEIGHT; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; STRATUM CORNEUM;

AMIDOHYDROLASES; CERAMIDES; DERMATITIS, ATOPIC; EPIDERMIS; GLUCOSYLCERAMIDES; HUMANS; PHOSPHORYLCHOLINE; PSYCHOSINE; SPHINGOMYELINS; SPHINGOSINE;

EID: 65649131175     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2009.04.006     Document Type: Review

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